HUT41022A - Process for preparing 2-halogen-6-methyl-ergol-9-ene derivatives and acid additional salts thereof - Google Patents

Process for preparing 2-halogen-6-methyl-ergol-9-ene derivatives and acid additional salts thereof

Info

Publication number
HUT41022A
HUT41022A HU852445A HU244585A HUT41022A HU T41022 A HUT41022 A HU T41022A HU 852445 A HU852445 A HU 852445A HU 244585 A HU244585 A HU 244585A HU T41022 A HUT41022 A HU T41022A
Authority
HU
Hungary
Prior art keywords
methyl
ergol
halogen
preparing
compositions
Prior art date
Application number
HU852445A
Other languages
English (en)
Other versions
HU193780B (en
Inventor
Gabor Megyeri
Tibor Keve
Bela Stefko
Janos Galambos
Erik Bogsch
Ferencne Kassai
Ferenc Trischler
Laszlo Szporny
Egon Karpati
Eva Palosi
Dora Groo
Zsolt Szombathelyi
Bela Kiss
Istvan Laszlovszky
Erzsebet Lapis
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU852445A priority Critical patent/HU193780B/hu
Priority to FI862636A priority patent/FI862636A/fi
Priority to AT86304765T priority patent/ATE73330T1/de
Priority to JP61143161A priority patent/JPS62425A/ja
Priority to DK291786A priority patent/DK291786A/da
Priority to DE8686304765T priority patent/DE3684186D1/de
Priority to EP86304765A priority patent/EP0208447B1/en
Priority to US06/877,298 priority patent/US4681887A/en
Publication of HUT41022A publication Critical patent/HUT41022A/hu
Publication of HU193780B publication Critical patent/HU193780B/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
HU852445A 1985-06-21 1985-06-21 Process for producing 2-halogeno-6-methyl-ergol-9-ene derivatives and acid additional salts thereof HU193780B (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
HU852445A HU193780B (en) 1985-06-21 1985-06-21 Process for producing 2-halogeno-6-methyl-ergol-9-ene derivatives and acid additional salts thereof
FI862636A FI862636A (fi) 1985-06-21 1986-06-19 Farmaceutiska kompositoner med neuroleptisk effekt och foerfarande foer deras framstaellning.
AT86304765T ATE73330T1 (de) 1985-06-21 1986-06-20 Verwendung von pharmaceutischen zusammensetzungen fuer die herstellung von arzneimitteln fuer die behandlung psychiatrischer stoerungen.
JP61143161A JPS62425A (ja) 1985-06-21 1986-06-20 医薬組成物
DK291786A DK291786A (da) 1985-06-21 1986-06-20 Neuroleptisk aktivt, farmaceutisk praeparat og fremgangsmaade til dets fremstilling
DE8686304765T DE3684186D1 (de) 1985-06-21 1986-06-20 Verwendung von pharmaceutischen zusammensetzungen fuer die herstellung von arzneimitteln fuer die behandlung psychiatrischer stoerungen.
EP86304765A EP0208447B1 (en) 1985-06-21 1986-06-20 Use of compositions for the manufacture of a medicament for the treatment of psychiatric disorders
US06/877,298 US4681887A (en) 1985-06-21 1986-06-23 Pharmaceutical compositions with a neuroleptic action and process for preparing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852445A HU193780B (en) 1985-06-21 1985-06-21 Process for producing 2-halogeno-6-methyl-ergol-9-ene derivatives and acid additional salts thereof

Publications (2)

Publication Number Publication Date
HUT41022A true HUT41022A (en) 1987-03-30
HU193780B HU193780B (en) 1987-11-30

Family

ID=10959389

Family Applications (1)

Application Number Title Priority Date Filing Date
HU852445A HU193780B (en) 1985-06-21 1985-06-21 Process for producing 2-halogeno-6-methyl-ergol-9-ene derivatives and acid additional salts thereof

Country Status (8)

Country Link
US (1) US4681887A (hu)
EP (1) EP0208447B1 (hu)
JP (1) JPS62425A (hu)
AT (1) ATE73330T1 (hu)
DE (1) DE3684186D1 (hu)
DK (1) DK291786A (hu)
FI (1) FI862636A (hu)
HU (1) HU193780B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
GB9707934D0 (en) * 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
US7666876B2 (en) * 2002-03-19 2010-02-23 Vernalis (R&D) Limited Buprenorphine formulations for intranasal delivery
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
CN103467296B (zh) * 2012-06-08 2016-03-09 上海医药工业研究院 一种3-溴-4-羟基苯甲酸甲酯的制备方法

Also Published As

Publication number Publication date
FI862636A (fi) 1986-12-22
JPH0368008B2 (hu) 1991-10-25
EP0208447A1 (en) 1987-01-14
JPS62425A (ja) 1987-01-06
DE3684186D1 (de) 1992-04-16
DK291786A (da) 1986-12-22
HU193780B (en) 1987-11-30
DK291786D0 (da) 1986-06-20
US4681887A (en) 1987-07-21
EP0208447B1 (en) 1992-03-11
FI862636A0 (fi) 1986-06-19
ATE73330T1 (de) 1992-03-15

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee