HUT38914A - Process for preparing cyclopropyl-amino acids and peptides, as well as sweetening agents and drinks comprising the above compounds - Google Patents

Process for preparing cyclopropyl-amino acids and peptides, as well as sweetening agents and drinks comprising the above compounds

Info

Publication number
HUT38914A
HUT38914A HU843555A HU355584A HUT38914A HU T38914 A HUT38914 A HU T38914A HU 843555 A HU843555 A HU 843555A HU 355584 A HU355584 A HU 355584A HU T38914 A HUT38914 A HU T38914A
Authority
HU
Hungary
Prior art keywords
drinks
peptides
well
amino acids
sweetening agents
Prior art date
Application number
HU843555A
Other languages
English (en)
Inventor
Charles H Stammer
Original Assignee
Univ Georgia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia filed Critical Univ Georgia
Publication of HUT38914A publication Critical patent/HUT38914A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU843555A 1983-08-16 1984-08-14 Process for preparing cyclopropyl-amino acids and peptides, as well as sweetening agents and drinks comprising the above compounds HUT38914A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52380883A 1983-08-16 1983-08-16
US63609184A 1984-08-03 1984-08-03
PCT/US1984/001278 WO1985000809A1 (en) 1983-08-16 1984-08-14 The synthesis of cyclopropane amino acids and peptides

Publications (1)

Publication Number Publication Date
HUT38914A true HUT38914A (en) 1986-07-28

Family

ID=27061274

Family Applications (1)

Application Number Title Priority Date Filing Date
HU843555A HUT38914A (en) 1983-08-16 1984-08-14 Process for preparing cyclopropyl-amino acids and peptides, as well as sweetening agents and drinks comprising the above compounds

Country Status (11)

Country Link
EP (1) EP0135429B1 (hu)
AU (1) AU579835B2 (hu)
DE (1) DE3485587D1 (hu)
DK (1) DK171385A (hu)
FI (1) FI851508L (hu)
HU (1) HUT38914A (hu)
MX (1) MX7527E (hu)
NO (1) NO851495L (hu)
OA (1) OA08010A (hu)
PT (1) PT79088B (hu)
WO (1) WO1985000809A1 (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3575761D1 (de) * 1984-11-02 1990-03-08 Toyota Motor Co Ltd Scharniermechanismus fuer eine kraftfahrzeugseitentuer.
JPS63500211A (ja) * 1984-12-11 1988-01-28 ユニバーシティ　オブ　ジョージャ　リサーチ　ファウンデーション　インコーポレーテッド 熱安定化されたペプチド甘味剤
WO1986003944A1 (en) * 1985-01-03 1986-07-17 Joyce Patrick J Heat stabilized peptide table salt substitutes
JPS63500634A (ja) * 1985-08-09 1988-03-10 ザ　ユニバ−シティ−　オブ　ジョ−ジア　リサ−チ　ファウンデ−ション、インコ−ポレ−テッド 安定化されたペプチド甘味料
CS277405B6 (en) * 1986-06-12 1993-03-17 Vyzk Ustav Farm Biochem Sp Peptides with 1-amino-1-cycloalkane carboxylic acid
WO1988007053A1 (en) * 1987-03-09 1988-09-22 The Upjohn Company Renin inhibitors containing a cyclopropyl amino acid and/or a cycloalkyl transition-state analogue
FR2652082B1 (fr) * 1989-09-15 1991-11-22 Rhone Poulenc Chimie Procede de preparation de l'acide-1 cyclopropanecarboxylique ou d'un de ses sels, produits de depart et leurs procedes de preparation.
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
EP0646242A4 (en) * 1991-11-12 1997-12-03 Promega Corp NON-RADIOACTIVE ENZYME ASSAY.
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
TWI344371B (en) * 2003-03-18 2011-07-01 Suntory Holdings Ltd Angiotensin-converting enzyme inhibitory peptides
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
CN114436731B (zh) * 2022-01-10 2023-07-11 北京航天试验技术研究所 一种环丙烷衍生物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3050559A (en) * 1962-08-21 Substituted phenylcyclopropylamjnes
DK326477A (da) * 1976-07-27 1978-01-28 Reckitt & Colmann Prod Ltd Kemiske forbindelser og fremgangsmade til fremstilling af samme
DE2936038A1 (de) * 1979-09-06 1981-03-26 Bayer Ag, 51373 Leverkusen Verfahren zur herstellung von 1-aminocyclopropan-carbonsaeure und deren derivaten
US4273704A (en) * 1979-12-03 1981-06-16 G. D. Searle & Co. N-Adamantane-substituted tetrapeptide amides

Also Published As

Publication number Publication date
PT79088B (en) 1986-08-14
FI851508A0 (fi) 1985-04-15
NO851495L (no) 1985-04-15
AU3314284A (en) 1985-03-12
DE3485587D1 (de) 1992-04-23
PT79088A (en) 1984-09-01
MX7527E (es) 1989-07-25
AU579835B2 (en) 1988-12-15
DK171385D0 (da) 1985-04-16
DK171385A (da) 1985-04-16
EP0135429A1 (en) 1985-03-27
EP0135429B1 (en) 1992-03-18
FI851508L (fi) 1985-04-15
OA08010A (fr) 1987-01-31
WO1985000809A1 (en) 1985-02-28

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Legal Events

Date Code Title Description
DFC9 Refusal of application