HUP9903978A2 - Proteinek glikozilezését inhibitáló vegyületek alkalmazása II. típusú diabetes kezelésére - Google Patents

Proteinek glikozilezését inhibitáló vegyületek alkalmazása II. típusú diabetes kezelésére

Info

Publication number
HUP9903978A2
HUP9903978A2 HU9903978A HUP9903978A HUP9903978A2 HU P9903978 A2 HUP9903978 A2 HU P9903978A2 HU 9903978 A HU9903978 A HU 9903978A HU P9903978 A HUP9903978 A HU P9903978A HU P9903978 A2 HUP9903978 A2 HU P9903978A2
Authority
HU
Hungary
Prior art keywords
type
diabetes
treatment
inhibitors
protein glycation
Prior art date
Application number
HU9903978A
Other languages
English (en)
Inventor
Valerie Piercy
Nicholas Charles Turner
Original Assignee
Smithkline Beecham Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9526330.7A external-priority patent/GB9526330D0/en
Priority claimed from GBGB9624914.9A external-priority patent/GB9624914D0/en
Application filed by Smithkline Beecham Plc. filed Critical Smithkline Beecham Plc.
Publication of HUP9903978A2 publication Critical patent/HUP9903978A2/hu
Publication of HUP9903978A3 publication Critical patent/HUP9903978A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Processing Of Solid Wastes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány II. típűsú diabetes kezelésére és/vagy megelőzéséreszőlgáló eljárásra vőnatkőzik, amelynek sőrán egy embernek vagynemhűmán emlősnek egy prőteinglikőzilezési inhibitőrnak, példáűlaminő-gűanidinnek vagy gyógyászatilag elfőgadható származékánakhatásős, nemtőxikűs, gyógyászatilag elfőgadható mennyiségét adják be.Az egyik előnyös találmány szerinti megőldás II. típűsú diabetesprőfilaktikűs kezelési eljárására, különösen a hyperinsűlinaemiától ahyperglykaemiáig terjedő prőgresszió késleltetésére vagymegakadályőzására vőnatkőzik. ŕ
HU9903978A 1995-12-22 1996-12-18 Use of inhibitors of protein glycation for the treatment of type ii diabetes HUP9903978A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9526330.7A GB9526330D0 (en) 1995-12-22 1995-12-22 Novel method
GBGB9624914.9A GB9624914D0 (en) 1996-11-29 1996-11-29 Novel method
PCT/EP1996/005870 WO1997023203A1 (en) 1995-12-22 1996-12-18 Aminoguanidine for treating niddm

Publications (2)

Publication Number Publication Date
HUP9903978A2 true HUP9903978A2 (hu) 2000-03-28
HUP9903978A3 HUP9903978A3 (en) 2001-01-29

Family

ID=26308373

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903978A HUP9903978A3 (en) 1995-12-22 1996-12-18 Use of inhibitors of protein glycation for the treatment of type ii diabetes

Country Status (18)

Country Link
EP (1) EP0868176B1 (hu)
JP (1) JP2000502667A (hu)
KR (1) KR19990076594A (hu)
CN (1) CN1209058A (hu)
AT (1) ATE369847T1 (hu)
AU (1) AU1307697A (hu)
BR (1) BR9612250A (hu)
CA (1) CA2240492A1 (hu)
CZ (1) CZ198798A3 (hu)
DE (1) DE69637209T2 (hu)
ES (1) ES2292176T3 (hu)
HU (1) HUP9903978A3 (hu)
IL (1) IL124869A0 (hu)
MX (1) MX9805099A (hu)
NO (1) NO982853L (hu)
PL (1) PL327471A1 (hu)
TR (1) TR199801120T2 (hu)
WO (1) WO1997023203A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20020625A1 (it) * 2002-12-17 2004-06-18 Sigma Tau Ind Farmaceuti Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'.
CN100411615C (zh) * 2003-12-12 2008-08-20 上海第二医科大学附属瑞金医院 氨基胍对难愈创面的防治作用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665192A (en) * 1984-03-19 1987-05-12 The Rockefeller University 2-(2-furoyl)-4(5)-2(furanyl)-1H-imidazole
WO1991012799A1 (en) * 1990-02-28 1991-09-05 The Upjohn Company Use of 3-guanidinopropionic acid in the treatment and prevention of metabolic disorders
AU3876995A (en) * 1994-11-17 1996-06-17 McDougall, Greg Electric fan heater

Also Published As

Publication number Publication date
JP2000502667A (ja) 2000-03-07
AU1307697A (en) 1997-07-17
BR9612250A (pt) 1999-07-13
NO982853D0 (no) 1998-06-19
ES2292176T3 (es) 2008-03-01
CN1209058A (zh) 1999-02-24
PL327471A1 (en) 1998-12-07
CA2240492A1 (en) 1997-07-03
MX9805099A (es) 1998-10-31
DE69637209D1 (de) 2007-09-27
WO1997023203A1 (en) 1997-07-03
EP0868176B1 (en) 2007-08-15
CZ198798A3 (cs) 1999-06-16
ATE369847T1 (de) 2007-09-15
DE69637209T2 (de) 2008-05-08
IL124869A0 (en) 1999-01-26
HUP9903978A3 (en) 2001-01-29
EP0868176A1 (en) 1998-10-07
NO982853L (no) 1998-06-19
KR19990076594A (ko) 1999-10-15
TR199801120T2 (xx) 1998-09-21

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