HUP9903506A2 - Grizeofulvin felhasználása rákok növekedésének gátlására - Google Patents
Grizeofulvin felhasználása rákok növekedésének gátlásáraInfo
- Publication number
- HUP9903506A2 HUP9903506A2 HU9903506A HUP9903506A HUP9903506A2 HU P9903506 A2 HUP9903506 A2 HU P9903506A2 HU 9903506 A HU9903506 A HU 9903506A HU P9903506 A HUP9903506 A HU P9903506A HU P9903506 A2 HUP9903506 A2 HU P9903506A2
- Authority
- HU
- Hungary
- Prior art keywords
- griseofulvin
- cancers
- inhibiting
- growth
- agents
- Prior art date
Links
- IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 title 1
- UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 title 1
- DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 title 1
- 230000005907 cancer growth Effects 0.000 title 1
- DDUHZTYCFQRHIY-RBHXEPJQSA-N griseofulvin Chemical compound COC1=CC(=O)C[C@@H](C)[C@@]11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-RBHXEPJQSA-N 0.000 title 1
- 229960002867 griseofulvin Drugs 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 102000015790 Asparaginase Human genes 0.000 abstract 1
- 108010024976 Asparaginase Proteins 0.000 abstract 1
- 241000498255 Enterobius vermicularis Species 0.000 abstract 1
- VSNHCAURESNICA-UHFFFAOYSA-N Hydroxyurea Chemical compound NC(=O)NO VSNHCAURESNICA-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000340 anti-metabolite Effects 0.000 abstract 1
- 239000002256 antimetabolite Substances 0.000 abstract 1
- 229940100197 antimetabolite Drugs 0.000 abstract 1
- 229960003272 asparaginase Drugs 0.000 abstract 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-M asparaginate Chemical compound [O-]C(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-M 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 206010014881 enterobiasis Diseases 0.000 abstract 1
- 229960001330 hydroxycarbamide Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány tárgya grizeőfűlvin és egy kemőterápiás ágens biztőnságősés hatásős mennyiségét, valamint valamilyen gyógyászatilag elfőgadhatóhőrdőzót és adőtt esetben egy pőtenciátőrt tartalmazógyógyszerkészítmény rák, tűmőrők és vírűsős fertőzések melegvérűállatőknál és az embernél való kezelésére. Az említett kemőterápiáságenst a DNS-interaktív ágensek, antimetabőlitők, tűbűlin-interaktívágensek, hőrmőnális ágensek, az aszparagináz vagy hidrőxi-karbamidközül választják. ŕ
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US183995P | 1995-08-03 | 1995-08-03 | |
| US67418196A | 1996-07-16 | 1996-07-16 | |
| PCT/US1996/012475 WO1997005870A2 (en) | 1995-08-03 | 1996-07-30 | Use of griseofulvin for inhibiting the growth of cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9903506A2 true HUP9903506A2 (hu) | 2000-06-28 |
| HUP9903506A3 HUP9903506A3 (en) | 2000-07-28 |
Family
ID=26669547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9903506A HUP9903506A3 (en) | 1995-08-03 | 1996-07-30 | Use of griseofulvin for inhibiting the growth of cancers |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0841914A2 (hu) |
| JP (1) | JPH11511136A (hu) |
| KR (1) | KR19990036137A (hu) |
| AR (1) | AR003176A1 (hu) |
| AU (1) | AU713031B2 (hu) |
| BR (1) | BR9609920A (hu) |
| CA (1) | CA2228503A1 (hu) |
| CZ (1) | CZ30598A3 (hu) |
| HU (1) | HUP9903506A3 (hu) |
| IL (1) | IL123094A0 (hu) |
| MX (1) | MX9800945A (hu) |
| NO (1) | NO980420L (hu) |
| PL (1) | PL324905A1 (hu) |
| SK (1) | SK14298A3 (hu) |
| TR (1) | TR199800244T2 (hu) |
| WO (1) | WO1997005870A2 (hu) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262093B1 (en) | 1995-04-12 | 2001-07-17 | The Proctor & Gamble Company | Methods of treating cancer with benzimidazoles |
| US6177460B1 (en) | 1995-04-12 | 2001-01-23 | The Procter & Gamble Company | Method of treatment for cancer or viral infections |
| US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
| US5770616A (en) | 1995-06-07 | 1998-06-23 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
| US6265427B1 (en) | 1995-06-07 | 2001-07-24 | The Proctor & Gamble Company | Pharmaceutical composition for the method of treating leukemia |
| US6686391B2 (en) | 1995-08-04 | 2004-02-03 | University Of Arizona Foundation | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions |
| US5900429A (en) | 1997-01-28 | 1999-05-04 | The Procter & Gamble Company | Method for inhibiting the growth of cancers |
| US6506783B1 (en) | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
| US6245789B1 (en) | 1998-05-19 | 2001-06-12 | The Procter & Gamble Company | HIV and viral treatment |
| US7635722B1 (en) * | 1998-07-27 | 2009-12-22 | Saint Jude Pharmaceuticals, Inc. | Chemical induced intracellular hyperthermia |
| ES2351149T3 (es) * | 1998-11-09 | 2011-02-01 | Biogen Idec Inc. | Anticuerpo quimérico dirigido contra cd20, el rituxan, para uso en el tratamiento de la leucemia linfocítica crónica. |
| US6423734B1 (en) | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
| US6407105B1 (en) | 2000-09-26 | 2002-06-18 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6380232B1 (en) | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
| US6462062B1 (en) | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6608096B1 (en) | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| DE60238408D1 (de) * | 2001-06-25 | 2011-01-05 | Ajinomoto Kk | Antitumorale mittel |
| EP2008652A1 (en) * | 2007-06-28 | 2008-12-31 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering |
| EP2204367A1 (en) | 2008-12-22 | 2010-07-07 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering |
-
1996
- 1996-07-30 HU HU9903506A patent/HUP9903506A3/hu unknown
- 1996-07-30 MX MX9800945A patent/MX9800945A/es unknown
- 1996-07-30 PL PL96324905A patent/PL324905A1/xx unknown
- 1996-07-30 BR BR9609920A patent/BR9609920A/pt unknown
- 1996-07-30 IL IL12309496A patent/IL123094A0/xx unknown
- 1996-07-30 JP JP9508495A patent/JPH11511136A/ja active Pending
- 1996-07-30 EP EP96926807A patent/EP0841914A2/en not_active Withdrawn
- 1996-07-30 KR KR1019980700805A patent/KR19990036137A/ko not_active Application Discontinuation
- 1996-07-30 SK SK142-98A patent/SK14298A3/sk unknown
- 1996-07-30 WO PCT/US1996/012475 patent/WO1997005870A2/en not_active Application Discontinuation
- 1996-07-30 AU AU66834/96A patent/AU713031B2/en not_active Ceased
- 1996-07-30 CA CA002228503A patent/CA2228503A1/en not_active Abandoned
- 1996-07-30 TR TR1998/00244T patent/TR199800244T2/xx unknown
- 1996-07-30 CZ CZ98305A patent/CZ30598A3/cs unknown
- 1996-08-02 AR ARP960103861A patent/AR003176A1/es not_active Application Discontinuation
-
1998
- 1998-01-30 NO NO980420A patent/NO980420L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL324905A1 (en) | 1998-06-22 |
| AU713031B2 (en) | 1999-11-18 |
| JPH11511136A (ja) | 1999-09-28 |
| AU6683496A (en) | 1997-03-05 |
| KR19990036137A (ko) | 1999-05-25 |
| NO980420D0 (no) | 1998-01-30 |
| NO980420L (no) | 1998-04-03 |
| AR003176A1 (es) | 1998-07-08 |
| HUP9903506A3 (en) | 2000-07-28 |
| EP0841914A2 (en) | 1998-05-20 |
| SK14298A3 (en) | 1998-09-09 |
| CZ30598A3 (cs) | 1998-06-17 |
| IL123094A0 (en) | 1998-09-24 |
| WO1997005870A3 (en) | 1997-04-17 |
| BR9609920A (pt) | 1999-07-06 |
| TR199800244T2 (xx) | 1998-09-21 |
| WO1997005870A2 (en) | 1997-02-20 |
| MX9800945A (es) | 1998-04-30 |
| CA2228503A1 (en) | 1997-02-20 |
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