HUP9902150A3 - Recombinant adenoviral vectors for human tumour gene therapy - Google Patents

Recombinant adenoviral vectors for human tumour gene therapy

Info

Publication number
HUP9902150A3
HUP9902150A3 HU9902150A HUP9902150A HUP9902150A3 HU P9902150 A3 HUP9902150 A3 HU P9902150A3 HU 9902150 A HU9902150 A HU 9902150A HU P9902150 A HUP9902150 A HU P9902150A HU P9902150 A3 HUP9902150 A3 HU P9902150A3
Authority
HU
Hungary
Prior art keywords
gene therapy
adenoviral vectors
recombinant adenoviral
human tumour
tumour gene
Prior art date
Application number
HU9902150A
Other languages
English (en)
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of HUP9902150A2 publication Critical patent/HUP9902150A2/hu
Publication of HUP9902150A3 publication Critical patent/HUP9902150A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU9902150A 1996-03-14 1997-03-12 Recombinant adenoviral vectors for human tumour gene therapy HUP9902150A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9603207A FR2746110B1 (fr) 1996-03-14 1996-03-14 Methode de traitement par therapie genique des tumeurs humaines et virus recombinants correspondants

Publications (2)

Publication Number Publication Date
HUP9902150A2 HUP9902150A2 (hu) 1999-11-29
HUP9902150A3 true HUP9902150A3 (en) 2000-12-28

Family

ID=9490181

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902150A HUP9902150A3 (en) 1996-03-14 1997-03-12 Recombinant adenoviral vectors for human tumour gene therapy

Country Status (19)

Country Link
US (1) US20030082150A1 (hu)
EP (1) EP0889969B1 (hu)
JP (1) JP2000507229A (hu)
KR (1) KR19990087718A (hu)
CN (1) CN1218512A (hu)
AT (1) ATE309382T1 (hu)
AU (1) AU732288B2 (hu)
BR (1) BR9707994A (hu)
CA (1) CA2248612A1 (hu)
CZ (1) CZ295967B6 (hu)
DE (1) DE69734574T2 (hu)
DK (1) DK0889969T3 (hu)
ES (1) ES2252779T3 (hu)
FR (1) FR2746110B1 (hu)
HU (1) HUP9902150A3 (hu)
IL (1) IL126152A0 (hu)
NO (1) NO984052D0 (hu)
SK (1) SK124698A3 (hu)
WO (1) WO1997034009A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998015638A2 (en) * 1996-10-07 1998-04-16 Ludwig Institute For Cancer Research Replication-defective adenoviruses for cancer immunotherapy
CA2388337C (en) 1999-10-22 2013-01-08 Aventis Pasteur Limited Method of inducing and/or enhancing an immune response to tumor antigens
CA2408328C (en) * 2000-05-10 2012-04-17 Aventis Pasteur Limited Immunogenic polypeptides encoded by mage minigenes and uses thereof
DE60238044D1 (de) * 2001-03-27 2010-12-02 Univ New York Tumortherapie mit vektoren auf sindbis virus-basis
AU2003223527B2 (en) 2002-04-09 2009-01-15 Sanofi Pasteur Limited Modified CEA nucleic acid and expression vectors
EP1497412A4 (en) * 2002-04-30 2006-11-22 Avior Therapeutics Inc ADENOVIRUS VECTORS FOR IMMUNOTHERAPY
CN1327000C (zh) * 2002-09-06 2007-07-18 中国人民解放军军事医学科学院基础医学研究所 靶向黑色素瘤的可复制性腺病毒穿梭载体及腺病毒
AU2003278036B2 (en) * 2002-10-22 2009-12-10 Aventis Pasteur Limited Anti-cancer vaccines and high-dose cytokines as adjuvants
EP1670926B1 (en) * 2003-10-08 2011-04-20 Sanofi Pasteur Limited Modified cea /b7 vector
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
CN117384961A (zh) 2016-02-23 2024-01-12 萨克生物研究学院 对病毒动力学影响最小的治疗性腺病毒中的外源基因表达
CA3013637A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
CA3045892A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235525B1 (en) * 1991-05-23 2001-05-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof
US5342774A (en) * 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5620886A (en) * 1993-03-18 1997-04-15 Ludwig Institute For Cancer Research Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2
CA2144040A1 (fr) * 1993-07-13 1995-01-26 Michel Perricaudet Vecteurs adenoviraux defectifs et utilisation en therapie genique

Also Published As

Publication number Publication date
CZ291598A3 (cs) 1998-12-16
BR9707994A (pt) 1999-07-27
SK124698A3 (en) 1999-05-07
FR2746110A1 (fr) 1997-09-19
WO1997034009A1 (fr) 1997-09-18
AU2164197A (en) 1997-10-01
US20030082150A1 (en) 2003-05-01
DK0889969T3 (da) 2006-03-27
JP2000507229A (ja) 2000-06-13
KR19990087718A (ko) 1999-12-27
CZ295967B6 (cs) 2005-12-14
HUP9902150A2 (hu) 1999-11-29
ES2252779T3 (es) 2006-05-16
CN1218512A (zh) 1999-06-02
NO984052L (no) 1998-09-03
ATE309382T1 (de) 2005-11-15
DE69734574T2 (de) 2006-07-13
FR2746110B1 (fr) 1998-04-17
DE69734574D1 (de) 2005-12-15
IL126152A0 (en) 1999-05-09
EP0889969A1 (fr) 1999-01-13
CA2248612A1 (fr) 1997-09-18
NO984052D0 (no) 1998-09-03
AU732288B2 (en) 2001-04-12
EP0889969B1 (fr) 2005-11-09

Similar Documents

Publication Publication Date Title
WO1996007734A3 (en) Recombinant adenovirus comprising a chimeric penton base protein
GB9622500D0 (en) Therapeutic gene
EP0963207A4 (en) GENE THERAPY AGAINST TUMORS BY INTERLEUKIN 12
AU2552795A (en) Safe vectors for gene therapy
ZA963434B (en) Gene therapy using replication competent targeted adenoviral vectors.
CA2213343A1 (en) Chimeric adenoviral fiber protein and methods of using same
EP1109896A4 (en) ADENOVIRUS FORMULATIONS FOR GENE THERAPY
AU3737297A (en) Bacteriophage-mediated gene therapy
HUP9902150A3 (en) Recombinant adenoviral vectors for human tumour gene therapy
AU8147194A (en) Recombinant adenoviruses for gene therapy in cancers
AU7077898A (en) Recombinant vectors derived from adeno-associated virus suitable for gene therapy
HUP0104046A3 (en) Adenovirus-mediated gene therapy
GB2322131B (en) Improved retroviral vectors for gene therapy
GB9419021D0 (en) Therapeutic protein
EP0954222A4 (en) GENE THERAPY FOR PROLIFERATIVE VITREORETINOPATHY
SI0889969T1 (sl) Rekombinantni adenovirusni vektorji za gensko terapijo humanih tumorjev
EP1084236A4 (en) NOVEL ADENOVIRAL VECTORS FOR GENE THERAPY
AU3036197A (en) Adenovirus vectors for gene therapy
GB9812550D0 (en) Tumour therapy and imaging
AU2350997A (en) Novel adenoviral vector for transferring human genes in vivo
EP0979277A4 (en) NEW GENE SUPPRESSOR FOR TUMORS OF MAN
GB9421223D0 (en) Tissue imaging in gene therapy
AU4068897A (en) Human induced tumor protein
GB2333527B (en) Therapeutic gene
ZA978019B (en) Gene therapy for congestive heart failure

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees