HUP9900858A2 - Methods and compositions for preparing soft gelatin capsules having shells resistant to permeation by fill materials - Google Patents
Methods and compositions for preparing soft gelatin capsules having shells resistant to permeation by fill materialsInfo
- Publication number
- HUP9900858A2 HUP9900858A2 HU9900858A HUP9900858A HUP9900858A2 HU P9900858 A2 HUP9900858 A2 HU P9900858A2 HU 9900858 A HU9900858 A HU 9900858A HU P9900858 A HUP9900858 A HU P9900858A HU P9900858 A2 HUP9900858 A2 HU P9900858A2
- Authority
- HU
- Hungary
- Prior art keywords
- filler
- outer layer
- gelatin capsules
- permeation
- compositions
- Prior art date
Links
- 239000007903 gelatin capsule Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000000463 material Substances 0.000 title 1
- 239000000945 filler Substances 0.000 abstract 5
- 239000004575 stone Substances 0.000 abstract 4
- 230000004888 barrier function Effects 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 238000000465 moulding Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000009987 spinning Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Laminated Bodies (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Materials For Medical Uses (AREA)
- Artificial Filaments (AREA)
Abstract
A találmány szerinti zselatinkapszűla a) legalább 1 külső rétegből és legalább 1 zárórétegből álló héjat és b) a héjban elhelyezett, szivattyúzható töltőanyagőt tartalmaz, ahől a záróréteg a külső réteg és a töltőanyag között van elhelyezve, a töltőanyag hidrőfil kőmpőnenst, hidrőfób kőmpőnenst, amfifilkőmpőnenst vagy ezekből képzett elegyet tartalmaz, a külső réteg zselatint tartalmaz, és a záróréteg a töltőanyagban lévőhidrőfil, amfifil és hidrőfób kőmpőnensek külső rétegbe irányűlómigrációját gátőlja, ahől a zselatinkapszűla főrgó rendszerű főrmázószerszámőt alkalmazóeljárással van előállítva. A találmány tárgyköréhez tartőzik tővábbáeljárás az őldószerrendszerre számítőtt 100 tömeg%-ig terjedőmennyiségben vízből álló töltőanyagőt tartalmazó zselatinkapszűlaelőállítására. ŕThe gelatin capsule according to the invention contains a) a shell consisting of at least 1 outer layer and at least 1 barrier layer and b) a pumpable filler placed in the shell, from which the barrier layer is placed between the outer layer and the filler, the filler is a hydrophilic stone component, a hydrophobic stone component, an amphiphilic stone component or it contains a mixture formed from these, the outer layer contains gelatin, and the closing layer prevents the migration of the hydrophilic, amphiphilic and hydrophobic stone components in the filler towards the outer layer, from which the gelatin capsule is produced using a main molding tool with a spinning system. The scope of the invention includes a further process for the production of gelatin capsules containing a filler consisting of water in an amount of up to 100% by weight of the solvent system. ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47289595A | 1995-06-07 | 1995-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP9900858A2 true HUP9900858A2 (en) | 1999-08-30 |
Family
ID=23877340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9900858A HUP9900858A2 (en) | 1995-06-07 | 1996-06-06 | Methods and compositions for preparing soft gelatin capsules having shells resistant to permeation by fill materials |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0837675A2 (en) |
| JP (1) | JPH11506785A (en) |
| KR (1) | KR19990022443A (en) |
| CN (1) | CN1186429A (en) |
| AU (1) | AU6154696A (en) |
| BR (1) | BR9608608A (en) |
| CA (1) | CA2222120A1 (en) |
| CZ (1) | CZ381897A3 (en) |
| HU (1) | HUP9900858A2 (en) |
| IL (1) | IL122422A0 (en) |
| NZ (1) | NZ310708A (en) |
| PL (1) | PL323790A1 (en) |
| SK (1) | SK164897A3 (en) |
| WO (1) | WO1996040083A2 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3188649B2 (en) * | 1997-05-09 | 2001-07-16 | 株式会社第一化成 | capsule |
| US6333047B1 (en) | 1997-05-09 | 2001-12-25 | Daiichi Kasei Co., Ltd. | Molded capsule superior in strength and stability and method for preparing same |
| EP0998270B1 (en) * | 1997-07-09 | 2005-01-12 | Swiss Caps Rechte und Lizenzen AG | Method and device for producing a multi-layer, physiologically tolerated presentation form |
| GB2398499B (en) * | 2000-02-16 | 2004-11-24 | Bioprogress Technology Ltd | Two layer capsules |
| CN1111419C (en) * | 2000-07-05 | 2003-06-18 | 宋令春 | A kind of medicine for the treatment of cardiovascular and cerebrovascular vessel apoplexy and premonitory apoplexy symptom and preparation method thereof |
| EP1498117A1 (en) * | 2003-07-15 | 2005-01-19 | Pfizer GmbH Arzneimittelwerk Gödecke | A pharmaceutical gelatin-capsule or gelatin containing capsule preparation showing an improved stability, a process for making the capsules and a process for improving the stability of gelatin-capsules |
| NL2000247C2 (en) * | 2006-09-25 | 2008-03-26 | Drie Mollen Holding B V | Capsule for coffee pod, has water disintegratable wall provided with hydrophobic coating on the inside |
| CN101596174B (en) * | 2009-07-13 | 2011-04-06 | 北京航洋胶囊技术有限公司 | Soft capsule and preparation method thereof |
| CN102552209A (en) * | 2012-01-06 | 2012-07-11 | 安徽黄山胶囊股份有限公司 | Double-layer hollow capsule and multi-layer enteric hollow capsule |
| CN103550065B (en) * | 2013-10-26 | 2015-01-28 | 中山市凯博思淀粉材料科技有限公司 | Method for producing starch-based soft capsule by compound extrusion |
| US20150209360A1 (en) * | 2014-01-30 | 2015-07-30 | Orbz, Llc | Oral caffeine delivery composition |
| CN107361392B (en) * | 2017-07-26 | 2019-10-25 | 云南芯韵科技开发有限公司 | A kind of three layers contain capsule with diuresis promoting function and preparation method thereof |
| US11298336B2 (en) | 2019-05-30 | 2022-04-12 | Soluble Technologies, Inc. | Water soluble formulation |
| CN113367379A (en) * | 2020-03-09 | 2021-09-10 | 深圳波顿香料有限公司 | Tobacco product |
| US11786475B2 (en) | 2020-07-22 | 2023-10-17 | Soluble Technologies Inc. | Film-based dosage form |
| CN115721627A (en) * | 2022-11-10 | 2023-03-03 | 南通华山药业有限公司 | Motherwort soft capsule and preparation method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0761948B2 (en) * | 1986-05-08 | 1995-07-05 | フロイント産業株式会社 | Capsules containing useful bacteria in the intestine |
| GB2290965A (en) * | 1994-07-11 | 1996-01-17 | Therapicon Srl | Multiple layer capsules for drugs |
| DE4432557A1 (en) * | 1994-09-13 | 1996-03-14 | Hoechst Ag | Capsules with a hydrophobic coating on the inside for receiving matrix-adsorbed aqueous (radioactive) solutions and method for producing the above capsules |
-
1996
- 1996-06-06 SK SK1648-97A patent/SK164897A3/en unknown
- 1996-06-06 CZ CZ973818A patent/CZ381897A3/en unknown
- 1996-06-06 AU AU61546/96A patent/AU6154696A/en not_active Abandoned
- 1996-06-06 PL PL96323790A patent/PL323790A1/en unknown
- 1996-06-06 HU HU9900858A patent/HUP9900858A2/en unknown
- 1996-06-06 CA CA002222120A patent/CA2222120A1/en not_active Abandoned
- 1996-06-06 NZ NZ310708A patent/NZ310708A/en unknown
- 1996-06-06 BR BR9608608-4A patent/BR9608608A/en not_active Application Discontinuation
- 1996-06-06 EP EP96919128A patent/EP0837675A2/en not_active Withdrawn
- 1996-06-06 CN CN96194414A patent/CN1186429A/en active Pending
- 1996-06-06 JP JP9501535A patent/JPH11506785A/en active Pending
- 1996-06-06 KR KR1019970708924A patent/KR19990022443A/en not_active Application Discontinuation
- 1996-06-06 IL IL12242296A patent/IL122422A0/en unknown
- 1996-06-06 WO PCT/US1996/009145 patent/WO1996040083A2/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SK164897A3 (en) | 1998-12-02 |
| CZ381897A3 (en) | 1998-05-13 |
| AU6154696A (en) | 1996-12-30 |
| MX9709198A (en) | 1998-03-31 |
| WO1996040083A3 (en) | 1997-02-06 |
| CA2222120A1 (en) | 1996-12-19 |
| BR9608608A (en) | 1999-12-07 |
| PL323790A1 (en) | 1998-04-27 |
| KR19990022443A (en) | 1999-03-25 |
| EP0837675A2 (en) | 1998-04-29 |
| NZ310708A (en) | 1999-11-29 |
| IL122422A0 (en) | 1998-06-15 |
| CN1186429A (en) | 1998-07-01 |
| WO1996040083A2 (en) | 1996-12-19 |
| JPH11506785A (en) | 1999-06-15 |
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