HUP9801744A3 - Method for the detection of compounds that modulate the effects of the obese protein - Google Patents

Method for the detection of compounds that modulate the effects of the obese protein

Info

Publication number
HUP9801744A3
HUP9801744A3 HU9801744A HUP9801744A HUP9801744A3 HU P9801744 A3 HUP9801744 A3 HU P9801744A3 HU 9801744 A HU9801744 A HU 9801744A HU P9801744 A HUP9801744 A HU P9801744A HU P9801744 A3 HUP9801744 A3 HU P9801744A3
Authority
HU
Hungary
Prior art keywords
modulate
compounds
detection
effects
obese protein
Prior art date
Application number
HU9801744A
Other languages
Hungarian (hu)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9510857.7A external-priority patent/GB9510857D0/en
Priority claimed from GBGB9511602.6A external-priority patent/GB9511602D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HUP9801744A2 publication Critical patent/HUP9801744A2/en
Publication of HUP9801744A3 publication Critical patent/HUP9801744A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU9801744A 1995-05-30 1996-05-28 Method for the detection of compounds that modulate the effects of the obese protein HUP9801744A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9510857.7A GB9510857D0 (en) 1995-05-30 1995-05-30 Novel assay
GBGB9511602.6A GB9511602D0 (en) 1995-06-08 1995-06-08 Novel assay

Publications (2)

Publication Number Publication Date
HUP9801744A2 HUP9801744A2 (en) 1998-10-28
HUP9801744A3 true HUP9801744A3 (en) 2000-06-28

Family

ID=26307107

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801744A HUP9801744A3 (en) 1995-05-30 1996-05-28 Method for the detection of compounds that modulate the effects of the obese protein

Country Status (15)

Country Link
EP (1) EP0832284A1 (en)
JP (1) JPH11505725A (en)
KR (1) KR19990022134A (en)
CN (1) CN1192248A (en)
AU (1) AU715215B2 (en)
BR (1) BR9608686A (en)
CA (1) CA2222409A1 (en)
CZ (1) CZ379097A3 (en)
HU (1) HUP9801744A3 (en)
MX (1) MX9709360A (en)
NO (1) NO975504L (en)
NZ (1) NZ309777A (en)
PL (1) PL323638A1 (en)
TR (1) TR199701469T1 (en)
WO (1) WO1996038586A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) * 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
JP2000511406A (en) * 1996-04-22 2000-09-05 メルク エンド カンパニー インコーポレーテッド Leptin assay
US6007998A (en) * 1996-04-22 1999-12-28 Merck & Co., Inc. Leptin assay
US6001816A (en) * 1996-06-20 1999-12-14 Merck & Co., Inc. Gene therapy for leptin deficiency
EP0951564A1 (en) * 1996-11-01 1999-10-27 Smithkline Beecham Plc Method for the detection of compounds that modulate the effects of the obese (ob) protein
IT1293533B1 (en) * 1997-07-14 1999-03-01 Angeletti P Ist Richerche Bio METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT
WO1999023493A1 (en) * 1997-10-31 1999-05-14 The Rockefeller University Methods of identifying agents that modulate leptin activity
CA2320226A1 (en) * 1998-02-11 1999-08-19 Beth Israel Deaconess Medical Center Methods and compositions for modulating leptin activity
GB9814199D0 (en) * 1998-06-30 1998-08-26 Univ Buckingham Novel method
GB9828087D0 (en) * 1998-12-18 1999-02-17 Smithkline Beecham Plc Novel method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995008001A1 (en) * 1993-09-15 1995-03-23 New York University Dna sequence which binds transcriptional regulatory proteins activated in response to various cytokines and uses thereof
CA2165057A1 (en) * 1994-04-14 1995-10-26 H. Martin Seidel Dna spacer regulatory elements responsive to cytokines and methods for their use

Also Published As

Publication number Publication date
PL323638A1 (en) 1998-04-14
CN1192248A (en) 1998-09-02
MX9709360A (en) 1998-02-28
WO1996038586A1 (en) 1996-12-05
NO975504D0 (en) 1997-11-28
NO975504L (en) 1997-11-28
BR9608686A (en) 1999-07-06
CA2222409A1 (en) 1996-12-05
EP0832284A1 (en) 1998-04-01
TR199701469T1 (en) 1998-03-21
KR19990022134A (en) 1999-03-25
NZ309777A (en) 2000-01-28
JPH11505725A (en) 1999-05-25
AU6002396A (en) 1996-12-18
AU715215B2 (en) 2000-01-20
CZ379097A3 (en) 1998-05-13
HUP9801744A2 (en) 1998-10-28

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