IT1293533B1 - METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT - Google Patents

METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT

Info

Publication number
IT1293533B1
IT1293533B1 IT97RM000428A ITRM970428A IT1293533B1 IT 1293533 B1 IT1293533 B1 IT 1293533B1 IT 97RM000428 A IT97RM000428 A IT 97RM000428A IT RM970428 A ITRM970428 A IT RM970428A IT 1293533 B1 IT1293533 B1 IT 1293533B1
Authority
IT
Italy
Prior art keywords
leptin
mimic
inhibit
molecules
enhance
Prior art date
Application number
IT97RM000428A
Other languages
Italian (it)
Inventor
Ralph Laufer
Gennaro Ciliberto
Marco Annalise Di
Anna Demartis
Isabelle Gloaguen
Paola Delmastro
Fang Chen
Der Ploeg Lex Van
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Priority to IT97RM000428A priority Critical patent/IT1293533B1/en
Publication of ITRM970428A0 publication Critical patent/ITRM970428A0/it
Priority to PCT/IT1998/000195 priority patent/WO1999004264A1/en
Priority to AU82412/98A priority patent/AU8241298A/en
Publication of ITRM970428A1 publication Critical patent/ITRM970428A1/en
Application granted granted Critical
Publication of IT1293533B1 publication Critical patent/IT1293533B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IT97RM000428A 1997-07-14 1997-07-14 METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT IT1293533B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT97RM000428A IT1293533B1 (en) 1997-07-14 1997-07-14 METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT
PCT/IT1998/000195 WO1999004264A1 (en) 1997-07-14 1998-07-14 Method for identifying modifiers of the leptin: leptin receptor interaction
AU82412/98A AU8241298A (en) 1997-07-14 1998-07-14 Method for identifying modifiers of the leptin: leptin receptor interaction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000428A IT1293533B1 (en) 1997-07-14 1997-07-14 METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT

Publications (3)

Publication Number Publication Date
ITRM970428A0 ITRM970428A0 (en) 1997-07-14
ITRM970428A1 ITRM970428A1 (en) 1999-01-14
IT1293533B1 true IT1293533B1 (en) 1999-03-01

Family

ID=11405174

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97RM000428A IT1293533B1 (en) 1997-07-14 1997-07-14 METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT

Country Status (3)

Country Link
AU (1) AU8241298A (en)
IT (1) IT1293533B1 (en)
WO (1) WO1999004264A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001025797A2 (en) * 1999-10-06 2001-04-12 Sumitomo Chemical Company, Limited Methods of evaluating whether a test agent is an agent affecting a leptin receptor
US6423739B1 (en) 2000-02-23 2002-07-23 Daiichi Pharmaceutical Co., Ltd. Method for aiding cerebral recovery following neurodegeneration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ379097A3 (en) * 1995-05-30 1998-05-13 Smithkline Beecham Plc Method of determining compounds which imitate, potentiate or inhibit physiological activity of obesity protein
DE69637211T2 (en) * 1995-12-11 2008-05-08 New England Medical Center Hospitals, Inc., Boston TESTING AND USE OF LIGANDS OF PEPTIDE HORMONE RECEPTORS.
AU1833197A (en) * 1996-01-18 1997-08-11 Progenitor, Inc. Detection of a leptin receptor variant and methods for regulating obesity
TR199900963T2 (en) * 1996-11-01 1999-08-23 Smithkline Beecham P.L.C. Method for detecting compounds that conform to the effects of the obese (OB) protein.

Also Published As

Publication number Publication date
ITRM970428A1 (en) 1999-01-14
ITRM970428A0 (en) 1997-07-14
AU8241298A (en) 1999-02-10
WO1999004264A1 (en) 1999-01-28

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Legal Events

Date Code Title Description
0001 Granted