HUP1600414A2 - Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény - Google Patents
Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítményInfo
- Publication number
- HUP1600414A2 HUP1600414A2 HU1600414A HUP1600414A HUP1600414A2 HU P1600414 A2 HUP1600414 A2 HU P1600414A2 HU 1600414 A HU1600414 A HU 1600414A HU P1600414 A HUP1600414 A HU P1600414A HU P1600414 A2 HUP1600414 A2 HU P1600414A2
- Authority
- HU
- Hungary
- Prior art keywords
- ramipril
- pharmaceutical composition
- composition containing
- stable pharmaceutical
- containing bisoprolol
- Prior art date
Links
- VHYCDWMUTMEGQY-UHFFFAOYSA-N bisoprolol Chemical compound CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1 VHYCDWMUTMEGQY-UHFFFAOYSA-N 0.000 title 1
- 229960002781 bisoprolol Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 title 1
- 229960003401 ramipril Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU1600414A HU231052B1 (hu) | 2013-08-16 | 2014-08-15 | Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUP1300496 | 2013-08-16 | ||
| HU1300496A HUP1300496A2 (hu) | 2013-08-16 | 2013-08-16 | Stabil kombinációs gyógyszerkészítmény |
| HU1600414A HU231052B1 (hu) | 2013-08-16 | 2014-08-15 | Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény |
| PCT/HU2014/000072 WO2015022560A1 (en) | 2013-08-16 | 2014-08-15 | Stable pharmaceutical composition containing bisoprolol and ramipril |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP1600414A2 true HUP1600414A2 (hu) | 2016-09-28 |
| HU231052B1 HU231052B1 (hu) | 2020-02-28 |
Family
ID=89991232
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU1300496A HUP1300496A2 (hu) | 2013-08-16 | 2013-08-16 | Stabil kombinációs gyógyszerkészítmény |
| HU1600414A HU231052B1 (hu) | 2013-08-16 | 2014-08-15 | Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU1300496A HUP1300496A2 (hu) | 2013-08-16 | 2013-08-16 | Stabil kombinációs gyógyszerkészítmény |
Country Status (3)
| Country | Link |
|---|---|
| EA (1) | EA033291B1 (hu) |
| HU (2) | HUP1300496A2 (hu) |
| WO (2) | WO2015022559A1 (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3501502A1 (en) * | 2017-12-20 | 2019-06-26 | Midas Pharma GmbH | Fixed dosed pharmaceutical compositions comprising amlodipine, ramipril and atorvastatin |
| WO2021162562A2 (en) | 2020-02-10 | 2021-08-19 | Adamed Pharma S.A. | Stable ramipril composition and fixed dose composition comprising thereof |
| CN115068434B (zh) * | 2022-08-03 | 2023-05-09 | 昆山龙灯瑞迪制药有限公司 | 一种雷米普利片的制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3174844D1 (en) | 1980-10-23 | 1986-07-24 | Schering Corp | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them |
| DE3226768A1 (de) | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
| DE3739690A1 (de) | 1987-11-24 | 1989-06-08 | Hoechst Ag | Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen |
| US20030215526A1 (en) | 2002-03-08 | 2003-11-20 | Scott Stofik | Stable formulations of angiotensin converting enzyme (ACE) inhibitors |
| WO2003092729A1 (de) * | 2002-05-03 | 2003-11-13 | Hexal Ag | Stabile pharmazeutische formulierung für eine kombination aus einem statin mit einem ace-hemmer |
| DK1635792T3 (da) | 2003-06-26 | 2009-06-15 | Teva Pharma | Stabile farmaceutiske sammensætninger af 2-aza-bicyklo-3.3.0-oktan-3-carboxylsyrederivater |
| AU2003300692A1 (en) | 2003-10-30 | 2005-05-19 | Lupin Ltd. | Stable formulations of ace inhibitors and methods for preparation thereof |
| GB2394660A (en) | 2003-12-17 | 2004-05-05 | Niche Generics Ltd | Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide |
| EA011862B1 (ru) | 2004-03-24 | 2009-06-30 | Актавис Груп Хф. | Композиции рамиприла |
| ZA200704767B (en) | 2004-11-05 | 2008-08-27 | King Pharmaceuticals Res & Dev | Stabilized individually coated ramipril particles, compositions and methods |
| US20070116762A1 (en) * | 2005-11-07 | 2007-05-24 | Wilson Edward S | Compositions of stabilized ramipril in combination with another active agent |
| CN100374462C (zh) | 2005-11-21 | 2008-03-12 | 大连帝恩生物工程有限公司 | 截短胰高血糖素样肽1(sGLP-1)、制法及其应用 |
| US20070232680A1 (en) | 2006-04-04 | 2007-10-04 | Vijayabhaskar Bolugoddu | Preparation of ramipril and stable pharmaceutical compositions |
| JP2009533461A (ja) | 2006-04-19 | 2009-09-17 | テバ ファーマシューティカル インダストリーズ リミティド | ２−アザ−ビシクロ［３．３．０］−オクタン−３−カルボン酸誘導体の安定な医薬組成物 |
| EP2034966A1 (en) | 2006-06-30 | 2009-03-18 | Alphapharm Pty Ltd. | A stabilised composition comprising ace inhibitors |
| US20110086092A1 (en) | 2006-08-08 | 2011-04-14 | Accu-Break Technologies, Inc. | Pharmacuetical tablets containing a plurality of active ingredients |
| WO2008065485A2 (en) | 2006-10-19 | 2008-06-05 | Torrent Pharmaceuticals Limited | Stable pharmaceutical compositions of a calcium channel blocker and an ace inhibitor |
| PT2120878E (pt) | 2007-02-09 | 2014-11-05 | Alphapharm Pty Ltd | Forma farmacêutica contendo duas ou mais substancias ativas em diferentes formas físicas |
| WO2008132756A1 (en) | 2007-05-01 | 2008-11-06 | Lupin Limited | Stable pharmaceutical compositions of ramipril |
| HU230877B1 (hu) | 2008-09-30 | 2018-11-29 | EGIS Gyógyszergyár NyR | Stabil kombinációs gyógyszerkészítmény |
| EP2272874A1 (en) | 2009-07-10 | 2011-01-12 | CSL Behring GmbH | Role of PLD1 in thrombus formation and integrin alpha IIb beta 3 activation |
| CN101612403A (zh) | 2009-08-13 | 2009-12-30 | 王丽燕 | 含钙拮抗剂、ace抑制剂和他汀类药的药物组合物 |
| CN104254321A (zh) | 2012-02-17 | 2014-12-31 | 埃吉斯药物私人有限公司 | 稳定性提高的药物制剂 |
-
2013
- 2013-08-16 HU HU1300496A patent/HUP1300496A2/hu not_active Application Discontinuation
-
2014
- 2014-08-15 WO PCT/HU2014/000071 patent/WO2015022559A1/en active Application Filing
- 2014-08-15 HU HU1600414A patent/HU231052B1/hu unknown
- 2014-08-15 EA EA201690395A patent/EA033291B1/ru not_active IP Right Cessation
- 2014-08-15 WO PCT/HU2014/000072 patent/WO2015022560A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015022559A1 (en) | 2015-02-19 |
| WO2015022560A8 (en) | 2015-05-14 |
| EA201690395A1 (ru) | 2016-07-29 |
| HU231052B1 (hu) | 2020-02-28 |
| WO2015022560A1 (en) | 2015-02-19 |
| HUP1300496A2 (hu) | 2015-03-02 |
| EA033291B1 (ru) | 2019-09-30 |
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