HUP0700370A2 - Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania - Google Patents

Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania

Info

Publication number
HUP0700370A2
HUP0700370A2 HU0700370A HUP0700370A HUP0700370A2 HU P0700370 A2 HUP0700370 A2 HU P0700370A2 HU 0700370 A HU0700370 A HU 0700370A HU P0700370 A HUP0700370 A HU P0700370A HU P0700370 A2 HUP0700370 A2 HU P0700370A2
Authority
HU
Hungary
Prior art keywords
carbamoyl
thio
medicament
manufacture
treatment
Prior art date
Application number
HU0700370A
Other languages
English (en)
Hungarian (hu)
Inventor
Istvan Dr Laszlovszky
Gyoergy Dr Nemeth
Gyoergy Dr Andor
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Priority to HU0700370A priority Critical patent/HUP0700370A2/hu
Publication of HU0700370D0 publication Critical patent/HU0700370D0/hu
Priority to MX2009012752A priority patent/MX2009012752A/es
Priority to US12/601,776 priority patent/US20100197704A1/en
Priority to AU2008252621A priority patent/AU2008252621B2/en
Priority to EP08762655.2A priority patent/EP2164572B2/en
Priority to EA200971087A priority patent/EA021936B1/ru
Priority to ES08762655.2T priority patent/ES2397962T5/es
Priority to PL08762655T priority patent/PL2164572T5/pl
Priority to DK08762655.2T priority patent/DK2164572T4/en
Priority to KR1020157016650A priority patent/KR20150076266A/ko
Priority to NZ582284A priority patent/NZ582284A/xx
Priority to GEAP200811619A priority patent/GEP20135731B/en
Priority to CN201510549993.2A priority patent/CN105193807A/zh
Priority to PCT/HU2008/000052 priority patent/WO2008142463A2/en
Priority to CA2687528A priority patent/CA2687528C/en
Priority to RS20130009A priority patent/RS52613B2/sr
Priority to SI200830879T priority patent/SI2164572T2/sl
Priority to CN200880017360A priority patent/CN101678212A/zh
Priority to PT87626552T priority patent/PT2164572E/pt
Priority to UAA200913520A priority patent/UA101323C2/ru
Priority to MYPI20094808A priority patent/MY148955A/en
Priority to JP2010508913A priority patent/JP2010527985A/ja
Priority to TW097125710A priority patent/TWI428130B/zh
Publication of HUP0700370A2 publication Critical patent/HUP0700370A2/hu
Priority to IL202048A priority patent/IL202048A/en
Priority to ZA200908283A priority patent/ZA200908283B/xx
Priority to HK10104405.9A priority patent/HK1136984A1/xx
Priority to CY20131100073T priority patent/CY1113566T1/el
Priority to HRP20130092TT priority patent/HRP20130092T4/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU0700370A 2007-05-24 2007-05-24 Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania HUP0700370A2 (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
HU0700370A HUP0700370A2 (en) 2007-05-24 2007-05-24 Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania
JP2010508913A JP2010527985A (ja) 2007-05-24 2008-05-19 急性躁病を治療するための医薬組成物および方法
CN201510549993.2A CN105193807A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类
CA2687528A CA2687528C (en) 2007-05-24 2008-05-19 Trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-n,n-dimethylcarbamoyl-cyclohexylamine for treating acute mania
AU2008252621A AU2008252621B2 (en) 2007-05-24 2008-05-19 Carbamoyl-cyclohexanes for treating acute mania
EP08762655.2A EP2164572B2 (en) 2007-05-24 2008-05-19 Carbamoyl-cyclohexanes for treating acute mania
EA200971087A EA021936B1 (ru) 2007-05-24 2008-05-19 Способ лечения острой мании
ES08762655.2T ES2397962T5 (es) 2007-05-24 2008-05-19 Carbamoil-ciclohexanos para el tratamiento de la manía aguda
PL08762655T PL2164572T5 (pl) 2007-05-24 2008-05-19 Karbamoilocykloheksany do leczenia ostrej manii
DK08762655.2T DK2164572T4 (en) 2007-05-24 2008-05-19 Carbamoyl-cyclohexanes FOR THE TREATMENT OF ACUTE MANI
KR1020157016650A KR20150076266A (ko) 2007-05-24 2008-05-19 급성 조증 치료용 카르바모일-시클로헥산
NZ582284A NZ582284A (en) 2007-05-24 2008-05-19 Carbamoyl-cyclohexanes for treating acute mania
GEAP200811619A GEP20135731B (en) 2007-05-24 2008-05-19 Trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-n,n-dimethyl carbamoyl-cyclohexylamine for acute mania treatment
MX2009012752A MX2009012752A (es) 2007-05-24 2008-05-19 Carbamoil-ciclohexanos para el tratamiento de la mania aguda.
PCT/HU2008/000052 WO2008142463A2 (en) 2007-05-24 2008-05-19 Carbamoyl-cyclohexanes for treating acute mania
US12/601,776 US20100197704A1 (en) 2007-05-24 2008-05-19 Pharmaceutical compositions and method for treating acute mania
RS20130009A RS52613B2 (sr) 2007-05-24 2008-05-19 Karbamoil-cikloheksani za lečenje akutne manije
SI200830879T SI2164572T2 (sl) 2007-05-24 2008-05-19 Karbamoil-cikloheksani za zdravljenje akutne manije
CN200880017360A CN101678212A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类
PT87626552T PT2164572E (pt) 2007-05-24 2008-05-19 Carbamoíl-ciclohexanos para o tratamento de manias agudas
UAA200913520A UA101323C2 (en) 2007-05-24 2008-05-19 Trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-n,n-dimethylcarbamoyl-cyclohexylamine for the treatment of acute mania
MYPI20094808A MY148955A (en) 2007-05-24 2008-05-19 Carbamoly-cyclohexanes for treating acute mania
TW097125710A TWI428130B (zh) 2007-05-24 2008-07-08 治療急性躁狂症之藥學組成物及方法
IL202048A IL202048A (en) 2007-05-24 2009-11-11 Use of carbamoyl-cyclohexanes for the preparation of a drug
ZA200908283A ZA200908283B (en) 2007-05-24 2009-11-23 Carbamoyl-cyclohexanes for treating acute mania
HK10104405.9A HK1136984A1 (en) 2007-05-24 2010-05-05 Carbamoyl-cyclohexanes for treating acute mania
CY20131100073T CY1113566T1 (el) 2007-05-24 2013-01-25 Καρβαμοϋλο-κυκλοεξανια για τη θεραπευτικη αγωγη της οξειας μανιας
HRP20130092TT HRP20130092T4 (hr) 2007-05-24 2013-02-04 Karbamoil-cikloheksani za lijeäśenje akutne manije

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0700370A HUP0700370A2 (en) 2007-05-24 2007-05-24 Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania

Publications (2)

Publication Number Publication Date
HU0700370D0 HU0700370D0 (en) 2007-07-30
HUP0700370A2 true HUP0700370A2 (en) 2009-04-28

Family

ID=89987541

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0700370A HUP0700370A2 (en) 2007-05-24 2007-05-24 Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania

Country Status (27)

Country Link
US (1) US20100197704A1 (US07981874-20110719-C00313.png)
EP (1) EP2164572B2 (US07981874-20110719-C00313.png)
JP (1) JP2010527985A (US07981874-20110719-C00313.png)
KR (1) KR20150076266A (US07981874-20110719-C00313.png)
CN (2) CN101678212A (US07981874-20110719-C00313.png)
AU (1) AU2008252621B2 (US07981874-20110719-C00313.png)
CA (1) CA2687528C (US07981874-20110719-C00313.png)
CY (1) CY1113566T1 (US07981874-20110719-C00313.png)
DK (1) DK2164572T4 (US07981874-20110719-C00313.png)
EA (1) EA021936B1 (US07981874-20110719-C00313.png)
ES (1) ES2397962T5 (US07981874-20110719-C00313.png)
GE (1) GEP20135731B (US07981874-20110719-C00313.png)
HK (1) HK1136984A1 (US07981874-20110719-C00313.png)
HR (1) HRP20130092T4 (US07981874-20110719-C00313.png)
HU (1) HUP0700370A2 (US07981874-20110719-C00313.png)
IL (1) IL202048A (US07981874-20110719-C00313.png)
MX (1) MX2009012752A (US07981874-20110719-C00313.png)
MY (1) MY148955A (US07981874-20110719-C00313.png)
NZ (1) NZ582284A (US07981874-20110719-C00313.png)
PL (1) PL2164572T5 (US07981874-20110719-C00313.png)
PT (1) PT2164572E (US07981874-20110719-C00313.png)
RS (1) RS52613B2 (US07981874-20110719-C00313.png)
SI (1) SI2164572T2 (US07981874-20110719-C00313.png)
TW (1) TWI428130B (US07981874-20110719-C00313.png)
UA (1) UA101323C2 (US07981874-20110719-C00313.png)
WO (1) WO2008142463A2 (US07981874-20110719-C00313.png)
ZA (1) ZA200908283B (US07981874-20110719-C00313.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0700353A2 (en) * 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
US7875610B2 (en) * 2007-12-03 2011-01-25 Richter Gedeon Nyrt. Pyrimidinyl-piperazines useful as D3/D2 receptor ligands
JP4409630B2 (ja) * 2008-02-21 2010-02-03 田辺三菱製薬株式会社 経口投与用固形製剤
NZ590852A (en) 2008-07-16 2013-03-28 Richter Gedeon Nyrt Pharmaceutical formulations containing dopamine receptor ligands trans-1{ 4-[2-[4-(2,3-dichlorophenyl)-piperizin-1-yl]-ethyl]-cyclohexyl} -3,3-dimethyl-urea also known as cariprazine
HU230067B1 (hu) 2008-12-17 2015-06-29 Richter Gedeon Nyrt Új piperazin só és eljárás előállítására
HUP0800766A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Vegyeszet Process for the preparation of piperazine derivatives
HUP0800765A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Nyrt A new process for the preparation of piperazine derivatives and their hydrochloric salts
US9610274B2 (en) * 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
WO2014031162A1 (en) 2012-08-20 2014-02-27 Forest Laboratories Holdings Limited Crystalline form of carbamoyl-cyclohexane derivatives
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0207832A (pt) * 2001-02-27 2004-06-22 Ortho Mcneil Pharm Inc Compostos de carbamato para uso na prevenção ou tratamento de distúrbio bipolar
HU227534B1 (en) * 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
PL2155200T3 (pl) * 2007-05-11 2017-06-30 Richter Gedeon Nyrt. Postać krystaliczna pochodnej karbamoilo-cykloheksanu

Also Published As

Publication number Publication date
ZA200908283B (en) 2010-08-25
CN105193807A (zh) 2015-12-30
CA2687528C (en) 2016-07-05
KR20150076266A (ko) 2015-07-06
SI2164572T1 (sl) 2013-02-28
ES2397962T5 (es) 2016-01-08
WO2008142463A3 (en) 2009-03-05
IL202048A0 (en) 2010-06-16
EP2164572A2 (en) 2010-03-24
EP2164572B2 (en) 2015-09-16
DK2164572T3 (da) 2013-02-11
US20100197704A1 (en) 2010-08-05
MX2009012752A (es) 2010-03-15
UA101323C2 (en) 2013-03-25
RS52613B2 (sr) 2018-05-31
MY148955A (en) 2013-06-14
PL2164572T5 (pl) 2016-02-29
HU0700370D0 (en) 2007-07-30
EA200971087A1 (ru) 2010-04-30
TWI428130B (zh) 2014-03-01
EP2164572B1 (en) 2012-11-14
HRP20130092T4 (hr) 2016-01-01
DK2164572T4 (en) 2016-01-04
ES2397962T3 (es) 2013-03-12
JP2010527985A (ja) 2010-08-19
PT2164572E (pt) 2013-01-28
PL2164572T3 (pl) 2013-04-30
GEP20135731B (en) 2013-01-25
SI2164572T2 (sl) 2016-01-29
TW201002326A (en) 2010-01-16
AU2008252621B2 (en) 2013-09-19
RS52613B (en) 2013-04-30
WO2008142463A2 (en) 2008-11-27
EA021936B1 (ru) 2015-10-30
CY1113566T1 (el) 2016-06-22
HRP20130092T1 (en) 2013-02-28
AU2008252621A1 (en) 2008-11-27
IL202048A (en) 2014-11-30
HK1136984A1 (en) 2010-07-16
CN101678212A (zh) 2010-03-24
NZ582284A (en) 2012-07-27
CA2687528A1 (en) 2008-11-27

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Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished