HUP0400975A2 - 4-[Fenil-(4-piperinilidén)-metil]-benzamid-származékok és alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
4-[Fenil-(4-piperinilidén)-metil]-benzamid-származékok és alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények Download PDFInfo
- Publication number
- HUP0400975A2 HUP0400975A2 HU0400975A HUP0400975A HUP0400975A2 HU P0400975 A2 HUP0400975 A2 HU P0400975A2 HU 0400975 A HU0400975 A HU 0400975A HU P0400975 A HUP0400975 A HU P0400975A HU P0400975 A2 HUP0400975 A2 HU P0400975A2
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- HU
- Hungary
- Prior art keywords
- methyl
- ylidene
- quinolyl
- piperidin
- compounds
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- -1 N-oxidopyridinyl group Chemical group 0.000 abstract description 21
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101768A SE0101768D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000947 WO2002094811A1 (en) | 2001-05-18 | 2002-05-16 | 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0400975A2 true HUP0400975A2 (hu) | 2004-08-30 |
Family
ID=20284171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0400975A HUP0400975A2 (hu) | 2001-05-18 | 2002-05-16 | 4-[Fenil-(4-piperinilidén)-metil]-benzamid-származékok és alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6838468B2 (enExample) |
| EP (1) | EP1395575B1 (enExample) |
| JP (1) | JP2005508858A (enExample) |
| KR (1) | KR20030094424A (enExample) |
| CN (1) | CN1527828A (enExample) |
| AR (1) | AR033757A1 (enExample) |
| AT (1) | ATE333452T1 (enExample) |
| BG (1) | BG108329A (enExample) |
| BR (1) | BR0209668A (enExample) |
| CA (1) | CA2446154A1 (enExample) |
| CO (1) | CO5540321A2 (enExample) |
| CZ (1) | CZ20033088A3 (enExample) |
| DE (1) | DE60213234T2 (enExample) |
| EE (1) | EE200300542A (enExample) |
| ES (1) | ES2268037T3 (enExample) |
| HU (1) | HUP0400975A2 (enExample) |
| IL (1) | IL158632A0 (enExample) |
| IS (1) | IS7025A (enExample) |
| MX (1) | MXPA03010437A (enExample) |
| NO (1) | NO20035117D0 (enExample) |
| PL (1) | PL366388A1 (enExample) |
| RU (1) | RU2003131969A (enExample) |
| SE (1) | SE0101768D0 (enExample) |
| SK (1) | SK13942003A3 (enExample) |
| WO (1) | WO2002094811A1 (enExample) |
| ZA (1) | ZA200308636B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0101768D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| RU2005136524A (ru) * | 2003-05-16 | 2006-06-27 | Астразенека Аб (Se) | Производные диарилметилиденпиперидина, способы их получения и их применение |
| KR20140015122A (ko) | 2003-10-01 | 2014-02-06 | 아돌로 코포레이션 | 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법 |
| SE0400026D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| WO2008033299A2 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of n-containing spirocompounds for the enhancement of cognitive function |
| MY148880A (en) * | 2006-10-20 | 2013-06-14 | Astrazeneca Ab | N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression |
| KR200453972Y1 (ko) * | 2009-08-31 | 2011-06-09 | (주)아모레퍼시픽 | 잔량확인이 가능한 에어리스 화장품용기 |
| SI3233825T1 (sl) * | 2014-12-19 | 2020-10-30 | Pharmnovo Ab | Derivati diarilmetiliden-piperidina in njihova uporaba kot agonisti delta opioidnega receptorja |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) * | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) * | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) * | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) * | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) * | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| US5574159A (en) * | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| CA2316341A1 (en) | 1997-12-24 | 1999-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
| SE0001207D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0001208D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0101768D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
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2001
- 2001-05-18 SE SE0101768A patent/SE0101768D0/xx unknown
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2002
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- 2002-05-16 BR BR0209668-4A patent/BR0209668A/pt not_active Application Discontinuation
- 2002-05-16 SK SK1394-2003A patent/SK13942003A3/sk unknown
- 2002-05-16 EE EEP200300542A patent/EE200300542A/xx unknown
- 2002-05-16 US US10/477,641 patent/US6838468B2/en not_active Expired - Fee Related
- 2002-05-16 CN CNA028101812A patent/CN1527828A/zh active Pending
- 2002-05-16 DE DE60213234T patent/DE60213234T2/de not_active Expired - Fee Related
- 2002-05-16 HU HU0400975A patent/HUP0400975A2/hu unknown
- 2002-05-16 CZ CZ20033088A patent/CZ20033088A3/cs unknown
- 2002-05-16 CA CA002446154A patent/CA2446154A1/en not_active Abandoned
- 2002-05-16 KR KR10-2003-7014945A patent/KR20030094424A/ko not_active Withdrawn
- 2002-05-16 RU RU2003131969/04A patent/RU2003131969A/ru not_active Application Discontinuation
- 2002-05-16 IL IL15863202A patent/IL158632A0/xx unknown
- 2002-05-16 JP JP2002591484A patent/JP2005508858A/ja active Pending
- 2002-05-16 AT AT02733704T patent/ATE333452T1/de not_active IP Right Cessation
- 2002-05-16 EP EP02733704A patent/EP1395575B1/en not_active Expired - Lifetime
- 2002-05-16 AR ARP020101813A patent/AR033757A1/es not_active Application Discontinuation
- 2002-05-16 ES ES02733704T patent/ES2268037T3/es not_active Expired - Lifetime
- 2002-05-16 MX MXPA03010437A patent/MXPA03010437A/es not_active Application Discontinuation
- 2002-05-16 PL PL02366388A patent/PL366388A1/xx not_active Application Discontinuation
-
2003
- 2003-11-05 ZA ZA200308636A patent/ZA200308636B/en unknown
- 2003-11-07 BG BG108329A patent/BG108329A/bg unknown
- 2003-11-11 IS IS7025A patent/IS7025A/is unknown
- 2003-11-12 CO CO03100162A patent/CO5540321A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035117A patent/NO20035117D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20040147553A1 (en) | 2004-07-29 |
| SK13942003A3 (sk) | 2004-04-06 |
| AR033757A1 (es) | 2004-01-07 |
| DE60213234T2 (de) | 2007-06-14 |
| IL158632A0 (en) | 2004-05-12 |
| BR0209668A (pt) | 2004-04-20 |
| IS7025A (is) | 2003-11-11 |
| RU2003131969A (ru) | 2005-05-10 |
| CO5540321A2 (es) | 2005-07-29 |
| DE60213234D1 (de) | 2006-08-31 |
| ES2268037T3 (es) | 2007-03-16 |
| BG108329A (bg) | 2004-12-30 |
| CA2446154A1 (en) | 2002-11-28 |
| JP2005508858A (ja) | 2005-04-07 |
| MXPA03010437A (es) | 2004-03-09 |
| WO2002094811A1 (en) | 2002-11-28 |
| KR20030094424A (ko) | 2003-12-11 |
| PL366388A1 (en) | 2005-01-24 |
| EP1395575B1 (en) | 2006-07-19 |
| SE0101768D0 (sv) | 2001-05-18 |
| EP1395575A1 (en) | 2004-03-10 |
| NO20035117D0 (no) | 2003-11-17 |
| US6838468B2 (en) | 2005-01-04 |
| CN1527828A (zh) | 2004-09-08 |
| ATE333452T1 (de) | 2006-08-15 |
| CZ20033088A3 (cs) | 2004-05-12 |
| ZA200308636B (en) | 2005-06-21 |
| EE200300542A (et) | 2004-02-16 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |