HUP0303958A2 - Heterociklusos oxi-, tioxi- és amino-benzazol-származékok, mint 5-hidroxitriptamin-6 ligandumok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
Heterociklusos oxi-, tioxi- és amino-benzazol-származékok, mint 5-hidroxitriptamin-6 ligandumok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0303958A2 HUP0303958A2 HU0303958A HUP0303958A HUP0303958A2 HU P0303958 A2 HUP0303958 A2 HU P0303958A2 HU 0303958 A HU0303958 A HU 0303958A HU P0303958 A HUP0303958 A HU P0303958A HU P0303958 A2 HUP0303958 A2 HU P0303958A2
- Authority
- HU
- Hungary
- Prior art keywords
- thioxy
- heterocyclyloxy
- hydroxytryptamine
- ligands
- preparation
- Prior art date
Links
- 125000005844 heterocyclyloxy group Chemical group 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28564301P | 2001-04-20 | 2001-04-20 | |
PCT/US2002/012415 WO2002085892A1 (en) | 2001-04-20 | 2002-04-19 | Heterocyclyloxy-, -thioxy- and -aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0303958A2 true HUP0303958A2 (hu) | 2004-04-28 |
Family
ID=23095111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0303958A HUP0303958A2 (hu) | 2001-04-20 | 2002-04-19 | Heterociklusos oxi-, tioxi- és amino-benzazol-származékok, mint 5-hidroxitriptamin-6 ligandumok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (17)
Country | Link |
---|---|
US (2) | US6815456B2 (hu) |
EP (1) | EP1385842A1 (hu) |
JP (1) | JP4323810B2 (hu) |
KR (1) | KR20030088508A (hu) |
CN (1) | CN1293072C (hu) |
AR (1) | AR035235A1 (hu) |
BR (1) | BR0209056A (hu) |
CA (1) | CA2444095A1 (hu) |
EA (1) | EA200301142A1 (hu) |
EC (2) | ECSP034811A (hu) |
HU (1) | HUP0303958A2 (hu) |
IL (1) | IL158445A0 (hu) |
MX (1) | MXPA03009476A (hu) |
NO (1) | NO20034648L (hu) |
PL (1) | PL367297A1 (hu) |
WO (1) | WO2002085892A1 (hu) |
ZA (1) | ZA200309004B (hu) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ529631A (en) * | 2001-06-07 | 2006-08-31 | F | Indole derivatives with 5-hydroxytryptamine (5-HT) 5-HT6 receptor affinity in the treatment of disorders of the CNS |
AU2003201149A1 (en) * | 2002-02-13 | 2003-09-04 | Koninklijke Philips Electronics N.V. | Integrated semiconductor optical device, method and apparatus for manufacturing such a device |
BR0311593A (pt) | 2002-06-05 | 2005-04-26 | Hoffmann La Roche | Derivados de 1-sulfonil-4-aminoalcoxi indol como moduladores de receptor 5-ht6 para tratamento dos distúrbios de snc |
PL377847A1 (pl) | 2003-01-14 | 2006-02-20 | Arena Pharmaceuticals Inc. | 1,2,3-Tripodstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie związanych z nim zaburzeń takich jak cukrzyca i hiperglikemia |
RU2347780C2 (ru) * | 2003-02-14 | 2009-02-27 | Уайт | Гетероциклил-3-сульфонилиндазолы в качестве лигандов 5-гидрокситриптамина-6 |
SE0302760D0 (sv) * | 2003-10-20 | 2003-10-20 | Biovitrum Ab | New compounds |
DE102004010132A1 (de) * | 2004-02-27 | 2005-09-15 | Merck Patent Gmbh | Piperidinderivate |
GB0422263D0 (en) * | 2004-10-07 | 2004-11-10 | Glaxo Group Ltd | Novel compounds |
DE602005011844D1 (de) * | 2004-11-02 | 2009-01-29 | Pfizer | Sulfonylbenzimidazolderivate |
DOP2006000010A (es) * | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | Procedimiento para preparar eteres aromáticos |
BRPI0606502A2 (pt) * | 2005-01-19 | 2009-06-30 | Hoffmann La Roche | compostos; processo para a fabricação de compostos; composições farmacêuticas; método para o tratamento ou prevenção de doenças que são associadas com a modulação de receptores h3; método para o tratamento ou prevenção de obesidade em um ser humano ou animal; método de tratamento ou prevenção de diabetes tipo ii em um ser humano ou animal e usos de compostos |
AU2006280091A1 (en) * | 2005-08-15 | 2007-02-22 | Wyeth | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands |
CA2619309A1 (en) * | 2005-08-15 | 2007-03-22 | Wyeth | Azinyl-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands |
MX2008012824A (es) * | 2006-04-05 | 2008-10-15 | Wyeth Corp | Derivados de sulfonil-3-heterociclilindazol como ligandos de 5-hidroxitriptamina-6. |
WO2007120596A1 (en) * | 2006-04-12 | 2007-10-25 | Wyeth | DIHYDRO[1,4]DIOXINO[2,3-e]INDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS |
CA2650082A1 (en) * | 2006-06-01 | 2007-12-13 | Wyeth | 1-sulfonylindazolylamine and -amide derivatives as 5-hydroxytryptamine-6 ligands |
US20090023925A1 (en) * | 2007-06-28 | 2009-01-22 | Wyeth | N'-(2-halobenzylidene)sulfonylhydrazides as intermediates in the manufacture of arylsulfonylindazoles |
WO2009034581A1 (en) * | 2007-09-11 | 2009-03-19 | Suven Life Sciences Limited | Substituted indolyl compounds and their use as 5-ht6 ligands |
US8293738B2 (en) | 2010-05-12 | 2012-10-23 | Abbott Laboratories | Indazole inhibitors of kinase |
BR112013008100A2 (pt) | 2010-09-22 | 2016-08-09 | Arena Pharm Inc | "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles." |
NZ608069A (en) | 2010-10-06 | 2014-06-27 | Glaxosmithkline Llc | Benzimidazole derivatives as pi3 kinase inhibitors |
JP6454346B2 (ja) | 2013-12-20 | 2019-01-16 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. | 芳香族複素環式化合物及び医薬におけるその応用 |
CN105541693B (zh) * | 2014-07-08 | 2018-10-16 | 广东东阳光药业有限公司 | 芳杂环类衍生物及其在药物上的应用 |
AU2016205361C1 (en) | 2015-01-06 | 2021-04-08 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
SI3310760T1 (sl) | 2015-06-22 | 2023-02-28 | Arena Pharmaceuticals, Inc. | Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1 |
KR20190116416A (ko) | 2017-02-16 | 2019-10-14 | 아레나 파마슈티칼스, 인크. | 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법 |
CN111233736B (zh) * | 2020-03-16 | 2021-07-16 | 东莞市东阳光新药研发有限公司 | 芳杂环类衍生物的盐及其用途 |
WO2024032530A1 (zh) * | 2022-08-11 | 2024-02-15 | 江苏恩华药业股份有限公司 | 芳杂环并环己烷基氨基烷基哌啶衍生物、制备方法及其用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3835291A1 (de) | 1988-04-19 | 1989-11-02 | Bayer Ag | 1,3-disubstituierte pyrrolidine |
GB9103862D0 (en) * | 1991-02-25 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
US5578716A (en) * | 1993-12-01 | 1996-11-26 | Mcgill University | DNA methyltransferase antisense oligonucleotides |
JPH0940646A (ja) | 1995-07-27 | 1997-02-10 | Yamanouchi Pharmaceut Co Ltd | ベンゼン縮合環誘導体又はその塩 |
AU7526798A (en) * | 1997-04-18 | 1998-11-27 | Smithkline Beecham Plc | Acetamide and urea derivatives, process for their preparation and their use in the treatment of cns disorders |
US6100291A (en) | 1998-03-16 | 2000-08-08 | Allelix Biopharmaceuticals Inc. | Pyrrolidine-indole compounds having 5-HT6 affinity |
WO2001002356A1 (fr) * | 1999-07-01 | 2001-01-11 | Sankyo Company, Limited | Dérivés d'indoline ou tétrahydroquinoline |
WO2001005758A2 (en) * | 1999-07-15 | 2001-01-25 | Nps Allelix Corp. | Indoles and indazoles for the treatment of migraine |
DK1355904T3 (da) * | 2000-12-22 | 2007-10-15 | Wyeth Corp | Heterocyclindazol- og -azaindazolforbindelser som 5-hydroxytryptamin-6-ligander |
TW593278B (en) * | 2001-01-23 | 2004-06-21 | Wyeth Corp | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands |
TW200401641A (en) * | 2002-07-18 | 2004-02-01 | Wyeth Corp | 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands |
RU2347780C2 (ru) * | 2003-02-14 | 2009-02-27 | Уайт | Гетероциклил-3-сульфонилиндазолы в качестве лигандов 5-гидрокситриптамина-6 |
-
2002
- 2002-04-19 BR BR0209056-2A patent/BR0209056A/pt not_active IP Right Cessation
- 2002-04-19 IL IL15844502A patent/IL158445A0/xx unknown
- 2002-04-19 JP JP2002583419A patent/JP4323810B2/ja not_active Expired - Fee Related
- 2002-04-19 CN CNB028123085A patent/CN1293072C/zh not_active Expired - Fee Related
- 2002-04-19 WO PCT/US2002/012415 patent/WO2002085892A1/en active Application Filing
- 2002-04-19 EA EA200301142A patent/EA200301142A1/ru unknown
- 2002-04-19 HU HU0303958A patent/HUP0303958A2/hu unknown
- 2002-04-19 PL PL02367297A patent/PL367297A1/xx unknown
- 2002-04-19 KR KR10-2003-7013585A patent/KR20030088508A/ko not_active Application Discontinuation
- 2002-04-19 CA CA002444095A patent/CA2444095A1/en not_active Abandoned
- 2002-04-19 EP EP02764248A patent/EP1385842A1/en not_active Withdrawn
- 2002-04-19 AR ARP020101442A patent/AR035235A1/es not_active Application Discontinuation
- 2002-04-19 US US10/126,598 patent/US6815456B2/en not_active Expired - Fee Related
- 2002-04-19 MX MXPA03009476A patent/MXPA03009476A/es active IP Right Grant
-
2003
- 2003-10-17 EC EC2003004811A patent/ECSP034811A/es unknown
- 2003-10-17 EC EC2003004810A patent/ECSP034810A/es unknown
- 2003-10-17 NO NO20034648A patent/NO20034648L/no not_active Application Discontinuation
- 2003-11-19 ZA ZA200309004A patent/ZA200309004B/en unknown
-
2004
- 2004-09-24 US US10/949,062 patent/US20050065186A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1385842A1 (en) | 2004-02-04 |
US20050065186A1 (en) | 2005-03-24 |
ECSP034810A (es) | 2003-12-01 |
IL158445A0 (en) | 2004-05-12 |
ZA200309004B (en) | 2005-02-21 |
NO20034648D0 (no) | 2003-10-17 |
JP4323810B2 (ja) | 2009-09-02 |
US20030069278A1 (en) | 2003-04-10 |
WO2002085892A1 (en) | 2002-10-31 |
NO20034648L (no) | 2003-11-20 |
JP2004526787A (ja) | 2004-09-02 |
CN1293072C (zh) | 2007-01-03 |
US6815456B2 (en) | 2004-11-09 |
KR20030088508A (ko) | 2003-11-19 |
AR035235A1 (es) | 2004-05-05 |
BR0209056A (pt) | 2004-08-10 |
CN1518547A (zh) | 2004-08-04 |
MXPA03009476A (es) | 2004-02-12 |
CA2444095A1 (en) | 2002-10-31 |
ECSP034811A (es) | 2003-12-01 |
EA200301142A1 (ru) | 2004-02-26 |
PL367297A1 (en) | 2005-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0401009A3 (en) | 1-aryl-or 1-alkylsulfonylbenzole derivatives as 5-hydroxytryptamine-6 ligands, process for their preparation and pharmaceutical compositions containing them | |
HUP0303958A2 (hu) | Heterociklusos oxi-, tioxi- és amino-benzazol-származékok, mint 5-hidroxitriptamin-6 ligandumok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
HUP0303756A3 (en) | 1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands and process for their preparation and pharmaceutical compositions containing them | |
HUP0402161A3 (en) | Nicotin-or isonicotin benzothiazole derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0402640A3 (en) | Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands, process for their preparation and pharmaceutical compositions thereof | |
HUP0400989A3 (en) | Substituted 2-pyridine-cyclohexane-1,4-diamine derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0203316A3 (en) | Amino-triazolopyridine derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0402225A3 (en) | Macrolide-compounds, process for their preparation and pharmaceutical compositions containing them | |
HUP0402026A3 (en) | 5,6-diaryl-pyrazine-2-amide derivatives as cb1 antagonists, process for their preparation and pharmaceutical compositions containing them | |
HU0103063D0 (en) | New 2h-pyridazin-3-one derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0201516A2 (en) | 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0303630A3 (en) | Imidazo-pyrimidine derivatives as ligands for gaba receptors, process for their preparation and pharmaceutical compositions containing them | |
HUP0201753A3 (en) | Pyridopyranoazepine derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0401747A3 (en) | Piridazine derivatives of hydrazono-malonitriles, their use, process for preparation of the compounds and pharmaceutical compositions containing the compounds | |
HUP0203184A3 (en) | Isoxazolecarboxamide derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0202731A3 (en) | O-anisamide derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0400317A3 (en) | Beta-carboline derivatives, process for their preparation, their use and pharmaceutical compositions containing them | |
HUP0201315A3 (en) | 4-phenyl-pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them | |
HUP0401082A3 (en) | Substituted 4-aminocyclohexanols, process for their preparation and pharmaceutical compositions containing them | |
HUP0303361A3 (en) | Substituted 1-aminobutan-3-ol derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0204001A3 (en) | Substituted aminomethyl-phenyl-cyclohexane derivatives, process for their preparation and pharmaceutical compositions containing them | |
AU2003231920A8 (en) | Antiinfectve compounds, process for their preparation and pharmaceutical compositions containing them | |
SI1245565T1 (en) | Indenoindolone derivatives, process for their preparation and pharmaceutical compositions containing them | |
HUP0203859A3 (en) | Aminomethyl-phenyl-cyclohexanone derivatives, process for their preparation, pharmaceutical compositions containing them and their use | |
HUP0400207A3 (en) | Substituted 4-aminocyclohexanol derivatives, process for their preparation and pharmaceutical compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |