HUP0300155A2 - Nitrilase from phodococcus rhodochrous ncimb 11216 - Google Patents

Nitrilase from phodococcus rhodochrous ncimb 11216

Info

Publication number
HUP0300155A2
HUP0300155A2 HU0300155A HUP0300155A HUP0300155A2 HU P0300155 A2 HUP0300155 A2 HU P0300155A2 HU 0300155 A HU0300155 A HU 0300155A HU P0300155 A HUP0300155 A HU P0300155A HU P0300155 A2 HUP0300155 A2 HU P0300155A2
Authority
HU
Hungary
Prior art keywords
nucleic acid
acid sequences
nitrilase
phodococcus
subject
Prior art date
Application number
HU0300155A
Other languages
English (en)
Inventor
Dirk Engels
Bernhard Hauer
Ralf Mattes
Marion Ress-Loeschke
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0300155A2 publication Critical patent/HUP0300155A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A találmány tárgyát nitriláz aktivitással rendelkező polipeptidetkódoló nukleinsavszekvenciák, a nukleinsavszekvenciákat tartalmazónukleinsav szerkezetek, valamint a nukleinsavszekvenciákat vagy anukleinsav szerkezeteket tartalmazó vektorok képezik. A találmánytárgyát képezik továbbá a nukleinsavszekvenciák által kódoltaminosavszekvenciák és a nukleinsavszekvenciákat, a nukleinsavszerkezeteket vagy a nukleinsavszekvenciákat vagy a nukleinsavszerkezeteket tartalmazó vektorokat tartalmazó mikroorganizmusok.Ezenkívül a találmány tárgyát képezi a megfelelő nitrilekbőlkarbonsavak előállítására szolgáló enzimes eljárás. Ó
HU0300155A 2000-03-03 2001-02-27 Nitrilase from phodococcus rhodochrous ncimb 11216 HUP0300155A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10010149A DE10010149A1 (de) 2000-03-03 2000-03-03 Nitrilase aus Rhodococcus rhodochrous NCIMB 11216
PCT/EP2001/002191 WO2001064857A1 (de) 2000-03-03 2001-02-27 Nitrilase aus rhodococcus rhodochrous ncimb 11216

Publications (1)

Publication Number Publication Date
HUP0300155A2 true HUP0300155A2 (en) 2003-05-28

Family

ID=7633225

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0300155A HUP0300155A2 (en) 2000-03-03 2001-02-27 Nitrilase from phodococcus rhodochrous ncimb 11216

Country Status (17)

Country Link
US (1) US20030157672A1 (hu)
EP (1) EP1268757A1 (hu)
JP (1) JP2003530832A (hu)
KR (1) KR20020077520A (hu)
CN (1) CN1411506A (hu)
AU (2) AU3380201A (hu)
BR (1) BR0108883A (hu)
CA (1) CA2400446A1 (hu)
DE (1) DE10010149A1 (hu)
HU (1) HUP0300155A2 (hu)
IL (1) IL151096A0 (hu)
MX (1) MXPA02008123A (hu)
NO (1) NO20024169L (hu)
PL (1) PL359496A1 (hu)
RU (1) RU2283864C2 (hu)
WO (1) WO2001064857A1 (hu)
ZA (1) ZA200207902B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118898B1 (en) 1999-10-26 2006-10-10 Showa Denko K.K. Rhodococcus bacterium, nitrilase gene, nitrylhydratase gene and amidase gene from Rhondococcus bacterium, and process for producing carboxylic acids by using them
US6562603B2 (en) 2000-08-04 2003-05-13 E. I. Du Pont De Nemours And Company 3-hydroxycarboxylic acid production and use in branched polymers
WO2004076655A1 (en) * 2003-02-27 2004-09-10 Basf Aktiengesellschaft Modified nitrilases and their use in methods for the production of carboxylic acids
US7148051B2 (en) * 2004-08-16 2006-12-12 E. I. Du Pont De Nemours And Company Production of 3-hydroxycarboxylic acid using nitrilase
CN102796769B (zh) * 2004-12-22 2014-06-04 纳幕尔杜邦公司 乙醇酸的酶促生产
JP2009508522A (ja) * 2005-09-22 2009-03-05 アストラゼネカ・アクチエボラーグ 芳香族ハロ−置換ジニトリルをハロ−置換シアノカルボン酸に変換する新規な方法
JP4977362B2 (ja) * 2005-12-09 2012-07-18 矢崎総業株式会社 ローラ
CN102690766A (zh) * 2012-05-15 2012-09-26 中国科学院青岛生物能源与过程研究所 筛选生产底物广泛性的腈水解酶的菌株的方法
FR3002542B1 (fr) * 2013-02-28 2016-01-22 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique et application a la synthese de l'ivabradine et de ses sels
CN103757068B (zh) * 2014-01-10 2016-06-29 江苏清泉化学股份有限公司 一种苯甲酸衍生物的制备方法
CN103898083B (zh) * 2014-04-21 2016-06-29 武汉大学 一种新型水解酶超家族酰胺酶Azl13及其制备与应用
CN113025601A (zh) * 2019-12-25 2021-06-25 上海奥博生物医药技术有限公司 腈水解酶启动子优化表达及应用
CN114539458B (zh) * 2020-11-26 2023-07-25 西安蓝晓科技新材料股份有限公司 一种应用于固相合成的多孔树脂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2623345B2 (ja) * 1988-06-27 1997-06-25 旭化成工業株式会社 光学活性なα―置換有機酸の製造方法
JP3009421B2 (ja) * 1990-02-28 2000-02-14 秀明 山田 有機酸の生物学的製造法
JPH0799980A (ja) * 1993-10-05 1995-04-18 Japan Energy Corp ニトリラーゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、およびこれを含有する形質転換体によるニトリル類からカルボン酸の製造法
US5628190A (en) * 1994-10-03 1997-05-13 Ormat Industries Ltd. Geothermal power plant and condenser therefor
GB9525372D0 (en) * 1995-12-12 1996-02-14 Allied Colloids Ltd Enzymes, their preparation and their use in the production of ammonium acrylate
DE19848129A1 (de) * 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten

Also Published As

Publication number Publication date
NO20024169D0 (no) 2002-09-02
CN1411506A (zh) 2003-04-16
ZA200207902B (en) 2004-03-29
RU2002126270A (ru) 2004-03-10
MXPA02008123A (es) 2002-11-29
US20030157672A1 (en) 2003-08-21
NO20024169L (no) 2002-11-01
AU2001233802B2 (en) 2006-01-12
JP2003530832A (ja) 2003-10-21
RU2283864C2 (ru) 2006-09-20
EP1268757A1 (de) 2003-01-02
AU3380201A (en) 2001-09-12
CA2400446A1 (en) 2001-09-07
BR0108883A (pt) 2003-04-29
KR20020077520A (ko) 2002-10-11
PL359496A1 (en) 2004-08-23
WO2001064857A1 (de) 2001-09-07
IL151096A0 (en) 2003-04-10
DE10010149A1 (de) 2001-09-06

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees