HUP0204050A3 - Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone - Google Patents
Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepironeInfo
- Publication number
- HUP0204050A3 HUP0204050A3 HU0204050A HUP0204050A HUP0204050A3 HU P0204050 A3 HUP0204050 A3 HU P0204050A3 HU 0204050 A HU0204050 A HU 0204050A HU P0204050 A HUP0204050 A HU P0204050A HU P0204050 A3 HUP0204050 A3 HU P0204050A3
- Authority
- HU
- Hungary
- Prior art keywords
- gepirone
- mirtazapine
- depression
- treatment
- related disorders
- Prior art date
Links
- 208000020401 Depressive disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000000890 drug combination Substances 0.000 title 1
- 229960000647 gepirone Drugs 0.000 title 1
- QOIGKGMMAGJZNZ-UHFFFAOYSA-N gepirone Chemical compound O=C1CC(C)(C)CC(=O)N1CCCCN1CCN(C=2N=CC=CN=2)CC1 QOIGKGMMAGJZNZ-UHFFFAOYSA-N 0.000 title 1
- 229960001785 mirtazapine Drugs 0.000 title 1
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00200189 | 2000-01-19 | ||
| PCT/EP2001/000407 WO2001052855A2 (en) | 2000-01-19 | 2001-01-15 | Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0204050A2 HUP0204050A2 (hu) | 2003-03-28 |
| HUP0204050A3 true HUP0204050A3 (en) | 2004-09-28 |
Family
ID=8170928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0204050A HUP0204050A3 (en) | 2000-01-19 | 2001-01-15 | Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6835728B2 (hu) |
| EP (1) | EP1251854A2 (hu) |
| JP (1) | JP2003520237A (hu) |
| KR (1) | KR20020068404A (hu) |
| CN (1) | CN1223349C (hu) |
| AR (1) | AR027240A1 (hu) |
| AU (1) | AU780817B2 (hu) |
| BR (1) | BR0107721A (hu) |
| CA (1) | CA2396066A1 (hu) |
| CO (1) | CO5261583A1 (hu) |
| HK (1) | HK1047548A1 (hu) |
| HU (1) | HUP0204050A3 (hu) |
| IL (1) | IL150289A0 (hu) |
| MX (1) | MXPA02007095A (hu) |
| NO (1) | NO20023448L (hu) |
| PE (1) | PE20011049A1 (hu) |
| PL (1) | PL356605A1 (hu) |
| RU (1) | RU2268725C2 (hu) |
| SK (1) | SK10552002A3 (hu) |
| WO (1) | WO2001052855A2 (hu) |
| ZA (1) | ZA200205161B (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7053092B2 (en) | 2001-01-29 | 2006-05-30 | Otsuka Pharmaceutical Co., Ltd. | 5-HT1a receptor subtype agonist |
| AR033485A1 (es) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
| WO2006023702A2 (en) * | 2004-08-20 | 2006-03-02 | Cypress Bioscience, Inc. | Method for treating sleep related breathing disorders with setiptiline |
| EP1827450A4 (en) * | 2004-11-17 | 2009-04-22 | Cypress Bioscience Inc | METHOD FOR REDUCING THE SIDE EFFECTS OF TREATMENT WITH MIRTAZAPINE |
| AR055424A1 (es) | 2005-09-12 | 2007-08-22 | Wyeth Corp | Formulacion de liberacion sostenida y usos de la misma |
| GT200600416A (es) | 2005-09-12 | 2007-09-20 | Sales salicilato y gentisato de un compuesto de piperazina | |
| GT200600414A (es) | 2005-09-12 | 2007-09-20 | Sal de glucuranato de compuesto de piperazine | |
| EP1792618A1 (en) * | 2005-11-30 | 2007-06-06 | Rainer Freynhagen | R-mirtazapine for the treatment of pain |
| CN101448805B (zh) * | 2006-05-22 | 2012-12-12 | Vanda制药公司 | 抑郁障碍的治疗 |
| TW200808804A (en) * | 2006-05-22 | 2008-02-16 | Organon Nv | Mirtazapine for the treatment of neuropathic pain |
| WO2008157094A1 (en) * | 2007-06-13 | 2008-12-24 | Cypress Bioscience, Inc. | Improving the tolerability of mirtazapine and a second active by using them in combination |
| DK2219603T3 (da) * | 2007-11-02 | 2014-09-01 | Acrux Dds Pty Ltd | Transdermalt afgivelsessystem |
| JP2013528180A (ja) | 2010-05-28 | 2013-07-08 | ジーイー・ヘルスケア・リミテッド | 放射性標識化合物及びその製造方法 |
| GB201112987D0 (en) | 2011-07-28 | 2011-09-14 | Ge Healthcare Ltd | Novel compound |
| CN108743593B (zh) * | 2018-08-31 | 2019-03-26 | 程世宏 | 一种抗抑郁药物及其口服颗粒剂和制药用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL189199C (nl) * | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
| US4423049A (en) * | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
| US4771053A (en) * | 1987-03-02 | 1988-09-13 | Bristol-Myers Company | Method for alleviation of primary depressive disorders |
| US5114976A (en) * | 1989-01-06 | 1992-05-19 | Norden Michael J | Method for treating certain psychiatric disorders and certain psychiatric symptoms |
| US5011841B1 (en) * | 1989-11-14 | 1994-09-06 | Pfizer | Treatment of depression |
| GB9303968D0 (en) * | 1993-02-26 | 1993-04-14 | Wyeth John & Brother Ltd | 5-ht1a ligands |
| GB9603136D0 (en) * | 1996-02-15 | 1996-04-17 | Merck Sharp & Dohme | Therapeutic agents |
| IL121076A (en) * | 1996-06-19 | 2000-10-31 | Akzo Nobel Nv | Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors |
| ZA982368B (en) * | 1997-03-27 | 1998-09-23 | Akzo Nobel Nv | New therapeutic combinations |
| TW587938B (en) | 1997-03-27 | 2004-05-21 | Akzo Nobel Nv | Pharmaceutical composition for the treatment and/or prophylaxis of psychotic disorder |
-
2001
- 2001-01-15 AU AU25162/01A patent/AU780817B2/en not_active Ceased
- 2001-01-15 EP EP01900449A patent/EP1251854A2/en not_active Withdrawn
- 2001-01-15 CA CA002396066A patent/CA2396066A1/en not_active Abandoned
- 2001-01-15 KR KR1020027009276A patent/KR20020068404A/ko not_active Application Discontinuation
- 2001-01-15 JP JP2001552902A patent/JP2003520237A/ja not_active Withdrawn
- 2001-01-15 RU RU2002122084/15A patent/RU2268725C2/ru not_active IP Right Cessation
- 2001-01-15 PL PL01356605A patent/PL356605A1/xx not_active Application Discontinuation
- 2001-01-15 WO PCT/EP2001/000407 patent/WO2001052855A2/en not_active Application Discontinuation
- 2001-01-15 BR BR0107721-0A patent/BR0107721A/pt not_active IP Right Cessation
- 2001-01-15 CN CNB018038654A patent/CN1223349C/zh not_active Expired - Fee Related
- 2001-01-15 MX MXPA02007095A patent/MXPA02007095A/es not_active Application Discontinuation
- 2001-01-15 HU HU0204050A patent/HUP0204050A3/hu unknown
- 2001-01-15 IL IL15028901A patent/IL150289A0/xx unknown
- 2001-01-15 US US10/181,843 patent/US6835728B2/en not_active Expired - Fee Related
- 2001-01-15 SK SK1055-2002A patent/SK10552002A3/sk not_active Application Discontinuation
- 2001-01-18 PE PE2001000055A patent/PE20011049A1/es not_active Application Discontinuation
- 2001-01-18 CO CO01003479A patent/CO5261583A1/es not_active Application Discontinuation
- 2001-01-18 AR ARP010100214A patent/AR027240A1/es not_active Application Discontinuation
-
2002
- 2002-06-27 ZA ZA200205161A patent/ZA200205161B/en unknown
- 2002-07-18 NO NO20023448A patent/NO20023448L/no not_active Application Discontinuation
- 2002-12-18 HK HK02109168.5A patent/HK1047548A1/zh unknown
-
2004
- 2004-11-22 US US10/996,213 patent/US20050090488A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2268725C2 (ru) | 2006-01-27 |
| MXPA02007095A (es) | 2003-04-14 |
| CN1395486A (zh) | 2003-02-05 |
| PL356605A1 (en) | 2004-06-28 |
| US20030105083A1 (en) | 2003-06-05 |
| AR027240A1 (es) | 2003-03-19 |
| SK10552002A3 (sk) | 2002-12-03 |
| JP2003520237A (ja) | 2003-07-02 |
| AU2516201A (en) | 2001-07-31 |
| WO2001052855A3 (en) | 2002-01-10 |
| US6835728B2 (en) | 2004-12-28 |
| KR20020068404A (ko) | 2002-08-27 |
| AU780817B2 (en) | 2005-04-21 |
| HK1047548A1 (zh) | 2003-02-28 |
| RU2002122084A (ru) | 2004-03-10 |
| IL150289A0 (en) | 2002-12-01 |
| NO20023448D0 (no) | 2002-07-18 |
| ZA200205161B (en) | 2003-09-29 |
| WO2001052855A8 (en) | 2002-12-27 |
| EP1251854A2 (en) | 2002-10-30 |
| CA2396066A1 (en) | 2001-07-26 |
| PE20011049A1 (es) | 2001-10-18 |
| CO5261583A1 (es) | 2003-03-31 |
| CN1223349C (zh) | 2005-10-19 |
| WO2001052855A2 (en) | 2001-07-26 |
| NO20023448L (no) | 2002-09-17 |
| BR0107721A (pt) | 2002-10-01 |
| HUP0204050A2 (hu) | 2003-03-28 |
| US20050090488A1 (en) | 2005-04-28 |
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