HUP0201663A2 - Induction of vascular endothelial growth factor (vegf) by the serine/threonine protein kinase akt - Google Patents

Induction of vascular endothelial growth factor (vegf) by the serine/threonine protein kinase akt

Info

Publication number
HUP0201663A2
HUP0201663A2 HU0201663A HUP0201663A HUP0201663A2 HU P0201663 A2 HUP0201663 A2 HU P0201663A2 HU 0201663 A HU0201663 A HU 0201663A HU P0201663 A HUP0201663 A HU P0201663A HU P0201663 A2 HUP0201663 A2 HU P0201663A2
Authority
HU
Hungary
Prior art keywords
vegf
serine
induction
growth factor
protein kinase
Prior art date
Application number
HU0201663A
Other languages
English (en)
Inventor
Kenneth Clark
Kun Guo
Yuri D Ivashchenko
Original Assignee
Aventis Pharm Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharm Prod Inc filed Critical Aventis Pharm Prod Inc
Publication of HUP0201663A2 publication Critical patent/HUP0201663A2/hu
Publication of HUP0201663A3 publication Critical patent/HUP0201663A3/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01037Protein kinase (2.7.1.37)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0201663A 1999-06-11 2000-06-01 Induction of vascular endothelial growth factor (vegf) by the serine/threonine protein kinase akt HUP0201663A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13872499P 1999-06-11 1999-06-11
GB9926058 1999-11-03

Publications (2)

Publication Number Publication Date
HUP0201663A2 true HUP0201663A2 (en) 2002-08-28
HUP0201663A3 HUP0201663A3 (en) 2005-01-28

Family

ID=26316052

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201663A HUP0201663A3 (en) 1999-06-11 2000-06-01 Induction of vascular endothelial growth factor (vegf) by the serine/threonine protein kinase akt

Country Status (17)

Country Link
EP (1) EP1187911A2 (hu)
JP (1) JP2003530818A (hu)
KR (1) KR20020012270A (hu)
CN (1) CN1360629A (hu)
AU (1) AU773450B2 (hu)
BR (1) BR0011503A (hu)
CA (1) CA2376630A1 (hu)
CZ (1) CZ20014444A3 (hu)
HK (1) HK1041500A1 (hu)
HU (1) HUP0201663A3 (hu)
IL (1) IL146730A0 (hu)
MX (1) MXPA01012748A (hu)
NO (1) NO20016025L (hu)
NZ (1) NZ516054A (hu)
PL (1) PL352859A1 (hu)
SI (1) SI20978A (hu)
WO (1) WO2000077190A2 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6881555B2 (en) 1999-03-19 2005-04-19 Aventis Pharmaceuticals Inc. AKT nucleic acids, polypeptides, and uses thereof
SI1144600T1 (sl) * 1999-03-19 2008-12-31 Aventis Pharma Inc AKT-3-nukleinske kisline, polipeptidi in njihove uporabe
HUP0200799A3 (en) 1999-04-16 2004-11-29 Univ Yale New Haven Enos mutations useful for gene therapy and therapeutic screening
US6187586B1 (en) * 1999-12-29 2001-02-13 Isis Pharmaceuticals, Inc. Antisense modulation of AKT-3 expression
ES2234818T3 (es) * 2000-03-02 2005-07-01 Ludwig Institute For Cancer Research Procedimiento para tratar canceres que expresan el factor de crecimiento endotelial d.
US20020102260A1 (en) 2000-03-02 2002-08-01 Marc Achen Methods for treating neoplastic disease characterized by vascular endothelial growth factor D expression, for screening for neoplastic disease or metastatic risk, and for maintaining vascularization of tissue
US7531318B2 (en) 2004-08-20 2009-05-12 Board Of Regents, The University Of Texas System Screening of agents for activity against ischemic myocardial insults

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1144600T1 (sl) * 1999-03-19 2008-12-31 Aventis Pharma Inc AKT-3-nukleinske kisline, polipeptidi in njihove uporabe

Also Published As

Publication number Publication date
PL352859A1 (en) 2003-09-08
BR0011503A (pt) 2002-03-05
CA2376630A1 (en) 2000-12-21
AU773450B2 (en) 2004-05-27
JP2003530818A (ja) 2003-10-21
IL146730A0 (en) 2002-07-25
HUP0201663A3 (en) 2005-01-28
KR20020012270A (ko) 2002-02-15
AU5175800A (en) 2001-01-02
WO2000077190A3 (en) 2001-04-12
MXPA01012748A (es) 2002-07-02
NO20016025L (no) 2002-02-08
HK1041500A1 (zh) 2002-07-12
EP1187911A2 (en) 2002-03-20
WO2000077190A2 (en) 2000-12-21
CZ20014444A3 (cs) 2002-05-15
NO20016025D0 (no) 2001-12-10
CN1360629A (zh) 2002-07-24
SI20978A (sl) 2003-02-28
NZ516054A (en) 2004-04-30

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