HUP0200455A2 - Eljárás 4-amino-5-klór-1-fenil-6-piridazinon előállítására - Google Patents
Eljárás 4-amino-5-klór-1-fenil-6-piridazinon előállításáraInfo
- Publication number
- HUP0200455A2 HUP0200455A2 HU0200455A HUP0200455A HUP0200455A2 HU P0200455 A2 HUP0200455 A2 HU P0200455A2 HU 0200455 A HU0200455 A HU 0200455A HU P0200455 A HUP0200455 A HU P0200455A HU P0200455 A2 HUP0200455 A2 HU P0200455A2
- Authority
- HU
- Hungary
- Prior art keywords
- chloro
- amino
- pyridazinone
- phenyl
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000003054 catalyst Substances 0.000 abstract 3
- WYKYKTKDBLFHCY-UHFFFAOYSA-N chloridazon Chemical compound O=C1C(Cl)=C(N)C=NN1C1=CC=CC=C1 WYKYKTKDBLFHCY-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000012429 reaction media Substances 0.000 abstract 2
- VKWCOHVAHQOJGU-UHFFFAOYSA-N 4,5-dichloro-2-phenylpyridazin-3-one Chemical compound O=C1C(Cl)=C(Cl)C=NN1C1=CC=CC=C1 VKWCOHVAHQOJGU-UHFFFAOYSA-N 0.000 abstract 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- 239000000908 ammonium hydroxide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
A találmány tárgya eljárás 4-amino-5-klór-1-fenil-6-piridazinonelőállítására 4,5-diklór-1-fenil-6-piridazinon vizes ammónium-hidroxid-oldattal katalizátor jelenlétében végzett reakciójával. Akatalizátor oldódik a vizes lúgos reakcióközegben, de lényegében nemoldódik, ha a reakcióközeget a 4-amino-5-klór-1-fenil-6-piridazinoneltávolítása után megsavanyítják. A találmány szerinti eljárásbanlehetőség van a katalizátor egyszerű módon való kinyerésére ésújrahasznosítására. Ó
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19914722 | 1999-03-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0200455A2 true HUP0200455A2 (hu) | 2002-05-29 |
HUP0200455A3 HUP0200455A3 (en) | 2003-01-28 |
Family
ID=7903157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0200455A HUP0200455A3 (en) | 1999-03-31 | 2000-03-30 | Method for producing 4-amino-5-chloro-1-phenyl pyridazinone-(6) |
Country Status (13)
Country | Link |
---|---|
US (1) | US6538135B1 (hu) |
EP (1) | EP1165520B1 (hu) |
CN (1) | CN1146546C (hu) |
AT (1) | ATE431820T1 (hu) |
AU (1) | AU771700B2 (hu) |
CZ (1) | CZ20013470A3 (hu) |
DE (1) | DE50015648D1 (hu) |
DK (1) | DK1165520T3 (hu) |
ES (1) | ES2325473T3 (hu) |
HU (1) | HUP0200455A3 (hu) |
PT (1) | PT1165520E (hu) |
SK (1) | SK286901B6 (hu) |
WO (1) | WO2000059891A1 (hu) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101638390B (zh) * | 2008-07-29 | 2012-12-05 | 上海合全药业有限公司 | 6-甲基-3-氨基哒嗪的工业化制备方法 |
CN103554032A (zh) * | 2013-11-12 | 2014-02-05 | 江苏正大清江制药有限公司 | 高光学纯度(-)-6-(4-氨基苯基)-4,5-二氢-5-甲基-3(2h)-哒嗪酮的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL245646A (hu) | 1960-03-19 | |||
AT260943B (de) | 1965-05-26 | 1968-03-25 | Pavel Dipl Ing Rapos | Verfahren zur Gewinnung von reinem 5-Amino-4-chlor-2-phenylpyridazin-3-on |
DE2937421A1 (de) | 1979-09-15 | 1981-04-09 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von 4-amino-5-chlor-1-phenylpyridazon-(6) |
WO1981001288A1 (en) * | 1979-10-31 | 1981-05-14 | Koege Kemisk Vaerk | Method for producing 4-chloro-5-amino-2-phenyl-3(2h)-pyridazinone from 4,5-dichloro-2-phenyl-3(2h)-pyridazinone and ammonia |
-
2000
- 2000-03-30 US US09/937,812 patent/US6538135B1/en not_active Expired - Fee Related
- 2000-03-30 EP EP00912664A patent/EP1165520B1/de not_active Expired - Lifetime
- 2000-03-30 HU HU0200455A patent/HUP0200455A3/hu unknown
- 2000-03-30 SK SK1317-2001A patent/SK286901B6/sk not_active IP Right Cessation
- 2000-03-30 CZ CZ20013470A patent/CZ20013470A3/cs unknown
- 2000-03-30 DE DE50015648T patent/DE50015648D1/de not_active Expired - Lifetime
- 2000-03-30 PT PT00912664T patent/PT1165520E/pt unknown
- 2000-03-30 AU AU34331/00A patent/AU771700B2/en not_active Ceased
- 2000-03-30 WO PCT/EP2000/002827 patent/WO2000059891A1/de active IP Right Grant
- 2000-03-30 CN CNB008066647A patent/CN1146546C/zh not_active Expired - Fee Related
- 2000-03-30 AT AT00912664T patent/ATE431820T1/de not_active IP Right Cessation
- 2000-03-30 ES ES00912664T patent/ES2325473T3/es not_active Expired - Lifetime
- 2000-03-30 DK DK00912664T patent/DK1165520T3/da active
Also Published As
Publication number | Publication date |
---|---|
EP1165520B1 (de) | 2009-05-20 |
SK13172001A3 (sk) | 2002-05-09 |
HUP0200455A3 (en) | 2003-01-28 |
WO2000059891A1 (de) | 2000-10-12 |
SK286901B6 (sk) | 2009-07-06 |
PT1165520E (pt) | 2009-06-02 |
DE50015648D1 (de) | 2009-07-02 |
ATE431820T1 (de) | 2009-06-15 |
CZ20013470A3 (cs) | 2002-03-13 |
US6538135B1 (en) | 2003-03-25 |
DK1165520T3 (da) | 2009-08-24 |
CN1348445A (zh) | 2002-05-08 |
AU3433100A (en) | 2000-10-23 |
ES2325473T3 (es) | 2009-09-07 |
CN1146546C (zh) | 2004-04-21 |
EP1165520A1 (de) | 2002-01-02 |
AU771700B2 (en) | 2004-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |