HUP0104272A2 - Új ciklobuténdionvegyületek, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyászati készítmények - Google Patents
Új ciklobuténdionvegyületek, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyászati készítményekInfo
- Publication number
- HUP0104272A2 HUP0104272A2 HU0104272A HUP0104272A HUP0104272A2 HU P0104272 A2 HUP0104272 A2 HU P0104272A2 HU 0104272 A HU0104272 A HU 0104272A HU P0104272 A HUP0104272 A HU P0104272A HU P0104272 A2 HUP0104272 A2 HU P0104272A2
- Authority
- HU
- Hungary
- Prior art keywords
- cyclobutendione
- compounds
- preparation
- new
- pharmaceutical compositions
- Prior art date
Links
- RGBVWCQARBEPPW-UHFFFAOYSA-N cyclobut-3-ene-1,2-dione Chemical class O=C1C=CC1=O RGBVWCQARBEPPW-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0013072A FR2815345B1 (fr) | 2000-10-12 | 2000-10-12 | Nouveaux derives de cyclobutene-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU0104272D0 HU0104272D0 (en) | 2001-12-28 |
| HUP0104272A2 true HUP0104272A2 (hu) | 2002-07-29 |
| HUP0104272A3 HUP0104272A3 (en) | 2004-01-28 |
Family
ID=8855275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0104272A HUP0104272A3 (en) | 2000-10-12 | 2001-10-12 | New cyclobutendione compounds, a process for their preparation and pharmaceutical compositions containing them |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6696469B2 (hu) |
| EP (1) | EP1197485B1 (hu) |
| JP (1) | JP3566685B2 (hu) |
| KR (1) | KR100511132B1 (hu) |
| CN (1) | CN1274675C (hu) |
| AR (1) | AR033683A1 (hu) |
| AT (1) | ATE273276T1 (hu) |
| AU (1) | AU781002B2 (hu) |
| BR (1) | BR0104471A (hu) |
| CA (1) | CA2358724C (hu) |
| DE (1) | DE60104791T2 (hu) |
| DK (1) | DK1197485T3 (hu) |
| EA (1) | EA004268B1 (hu) |
| ES (1) | ES2227092T3 (hu) |
| FR (1) | FR2815345B1 (hu) |
| HK (1) | HK1045517B (hu) |
| HU (1) | HUP0104272A3 (hu) |
| MX (1) | MXPA01010049A (hu) |
| NO (1) | NO320702B1 (hu) |
| NZ (1) | NZ514758A (hu) |
| PL (1) | PL350104A1 (hu) |
| PT (1) | PT1197485E (hu) |
| SI (1) | SI1197485T1 (hu) |
| TR (1) | TR200402070T4 (hu) |
| ZA (1) | ZA200108404B (hu) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7714130B2 (en) | 2004-06-17 | 2010-05-11 | Wyeth | Processes for preparing gonadotropin releasing hormone receptor antagonists |
| WO2006009734A1 (en) | 2004-06-17 | 2006-01-26 | Wyeth | Gonadotropin releasing hormone receptor antagonists |
| JP2008520732A (ja) * | 2004-11-23 | 2008-06-19 | ワイス | ゴナドトロピン放出ホルモン受容体アンタゴニスト |
| ATE432921T1 (de) * | 2004-12-23 | 2009-06-15 | Gpc Biotech Ag | Quadratsäurederivate mit antiproliferativer wirkung |
| US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US20060189619A1 (en) * | 2005-02-24 | 2006-08-24 | Wyeth | 3-({4-[2-(4-Tert-butylphenyl)-1h-benzimidazol-4-yl]piperazin-1-yl}methyl)pyrido[2,3-b]]pyrazi ne compounds |
| US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
| US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
| US8450348B2 (en) * | 2007-02-21 | 2013-05-28 | Forma Tm, Llc | Derivatives of squaric acid with anti-proliferative activity |
| RU2529468C2 (ru) | 2008-06-24 | 2014-09-27 | Топотаргет А/С | Производные 1, 2-дигидроциклобутендиона в качестве ингибиторов фосфорибозилтрансферазы никотинамида |
| BR112014004963A2 (pt) | 2011-09-02 | 2017-03-21 | Novartis Ag | sal de colina do composto anti-inflamatório ciclobutanodiona substituído |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE251613T1 (de) * | 1998-08-21 | 2003-10-15 | Smithkline Beecham Plc | Pyrimidinonderivate zur behandlung von atheroscleros |
| EP1140792A1 (en) * | 1998-12-14 | 2001-10-10 | American Home Products Corporation | 3,4-diamino-3-cyclobutene-1,2-dione derivatives which inhibit leukocyte adhesion mediated by vla-4 |
| US6432960B2 (en) * | 2000-05-10 | 2002-08-13 | Bristol-Myers Squibb Company | Squarate derivatives of dihydropyridine NPY antagonists |
-
2000
- 2000-10-12 FR FR0013072A patent/FR2815345B1/fr not_active Expired - Fee Related
-
2001
- 2001-10-05 MX MXPA01010049A patent/MXPA01010049A/es active IP Right Grant
- 2001-10-09 BR BR0104471-0A patent/BR0104471A/pt not_active IP Right Cessation
- 2001-10-09 JP JP2001311565A patent/JP3566685B2/ja not_active Expired - Fee Related
- 2001-10-11 AT AT01402623T patent/ATE273276T1/de not_active IP Right Cessation
- 2001-10-11 CA CA002358724A patent/CA2358724C/fr not_active Expired - Fee Related
- 2001-10-11 SI SI200130164T patent/SI1197485T1/xx unknown
- 2001-10-11 EP EP01402623A patent/EP1197485B1/fr not_active Expired - Lifetime
- 2001-10-11 AR ARP010104769A patent/AR033683A1/es unknown
- 2001-10-11 DK DK01402623T patent/DK1197485T3/da active
- 2001-10-11 NO NO20014945A patent/NO320702B1/no not_active IP Right Cessation
- 2001-10-11 NZ NZ514758A patent/NZ514758A/xx unknown
- 2001-10-11 PT PT01402623T patent/PT1197485E/pt unknown
- 2001-10-11 DE DE60104791T patent/DE60104791T2/de not_active Expired - Fee Related
- 2001-10-11 ES ES01402623T patent/ES2227092T3/es not_active Expired - Lifetime
- 2001-10-11 TR TR2004/02070T patent/TR200402070T4/xx unknown
- 2001-10-12 EA EA200100969A patent/EA004268B1/ru unknown
- 2001-10-12 US US09/976,572 patent/US6696469B2/en not_active Expired - Fee Related
- 2001-10-12 AU AU79386/01A patent/AU781002B2/en not_active Ceased
- 2001-10-12 HU HU0104272A patent/HUP0104272A3/hu unknown
- 2001-10-12 PL PL01350104A patent/PL350104A1/xx not_active Application Discontinuation
- 2001-10-12 CN CNB011412968A patent/CN1274675C/zh not_active Expired - Fee Related
- 2001-10-12 KR KR10-2001-0062988A patent/KR100511132B1/ko not_active IP Right Cessation
- 2001-10-12 ZA ZA200108404A patent/ZA200108404B/xx unknown
-
2002
- 2002-09-26 HK HK02107053.7A patent/HK1045517B/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0002843A3 (en) | New betha-carboline compounds, a process for their preparation and pharmaceutical compositions containing them | |
| HK1042698B (zh) | 新的二苯脲化合物、其製備方法和含有該化合物的藥物組合物 | |
| HUP0301187A3 (en) | Novel benzyl-piperidine-derivatives, process for their preparation and pharmaceutical compositions containing them | |
| HK1039117B (zh) | 新的哌啶-4-磺酰胺化合物、其製備方法和含有它們的藥物組合物 | |
| PL359373A1 (en) | New substituted phthalides, a process for their preparation and pharmaceutical compositions containing them | |
| HUP0104272A3 (en) | New cyclobutendione compounds, a process for their preparation and pharmaceutical compositions containing them | |
| HUP0302515A3 (en) | Sulfanidothienopyrimidines, process for their preparation and pharmaceutical compositions containing them | |
| HK1038912A1 (en) | New benzenesulphonamide compounds, a process for their preparation and pharmaceutical compositions containing them. | |
| HUP0301254A3 (en) | Novel compounds, process fo their preparation and pharmaceutical compositions containing them | |
| HK1049159B (zh) | 新的茚並吲哚酮化合物，其製備方法和含有這種化合物的藥物組合物 | |
| PL360090A1 (en) | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | |
| HK1049000B (zh) | 異吲並吲酮化合物、它們的製備方法和含有它們的藥物組合物 | |
| HUP0302905A3 (en) | Triazolo-epothilone-analogs, process for their preparation and pharmaceutical compositions containing them | |
| HK1042094B (zh) | 新型苯並噻二嗪化合物，其製備方法及含它們的藥物組合物 | |
| HUP0105328A3 (en) | Bicyclic amino-pirazinone compounds, a process for their preparation and pharmaceutical compositions containing them | |
| HK1053646A1 (en) | BenzoÄBÜpyranoÄ3,2-HÜacridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them | |
| ZA200205666B (en) | N-benzylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them. | |
| HK1040247A1 (zh) | 新穎的環丁烷並吲羧酰胺化合物、其製備方法和含有它們的藥物組合物 | |
| ZA200103065B (en) | Heterocycloalkylbenzocyclobutane and heteroarylbenzocyclobutane compounds, a process for their preparation and pharmaceutical compositions containing them. | |
| HUP0004543A3 (en) | Aminopyrroline compounds, process for their preparation and pharmaceutical compositions containing them | |
| HK1040518A1 (zh) | 新的6-氨基或6-肼基-磺酰基3-喹啉基膦酸化合物、其製備方法及含有它們的藥物組合物 | |
| ZA200204757B (en) | Indenoidolone compounds, a process for their preparation and pharmaceutical compositions containing them. | |
| HK1039619A1 (zh) | 新的-6-氨磺酰-3-喹啉基膦酸化合物，其制備方法及含有它們的藥物組合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |