HUP0103544A2 - (R)-3-(N,N-diciklobutil amino)-8-fluor-3,4dihidro-2H-1-benzopirán-5karboxamid-hidrogén-(2R,3R)tartarát monohidrátot és paroxelint tartalmazó gyógyszerkészítmény és eljárás az előállítására - Google Patents
(R)-3-(N,N-diciklobutil amino)-8-fluor-3,4dihidro-2H-1-benzopirán-5karboxamid-hidrogén-(2R,3R)tartarát monohidrátot és paroxelint tartalmazó gyógyszerkészítmény és eljárás az előállításáraInfo
- Publication number
- HUP0103544A2 HUP0103544A2 HU0103544A HUP0103544A HUP0103544A2 HU P0103544 A2 HUP0103544 A2 HU P0103544A2 HU 0103544 A HU0103544 A HU 0103544A HU P0103544 A HUP0103544 A HU P0103544A HU P0103544 A2 HUP0103544 A2 HU P0103544A2
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- benzopyran
- dihydro
- fluoro
- carboxamide
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 5
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229960002296 paroxetine Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- MQTUXRKNJYPMCG-CYBMUJFWSA-N robalzotan Chemical compound C1CCC1N([C@H]1COC=2C(F)=CC=C(C=2C1)C(=O)N)C1CCC1 MQTUXRKNJYPMCG-CYBMUJFWSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A találmány tárgyát első (a) komponensként (R)-3-(N,N-diciklobutil-amino)-8-fluor-3,4-dihidro-2H-1-benzopirán-5-karboxamid-hid- rogén-(2R,3R)-tartarát-monohidrátot, második (b) komponensként pedigparoxetint szabad bázis vagy gyógyszerészetileg elfogadható sójaés/vagy szolvátja formájában tartalmazó készítmény képezi. A találmánytárgya továbbá a készítmény előállítása, a készítményt tartalmazógyógyszerkészítmények és alkalmazásuk ingerlékeny rendellenességek,például hangulati rendellenességek és szorongásos rendellenességekkezelésére, és a készítményt tartalmazó készlet. Ó
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9803156A SE9803156D0 (sv) | 1998-09-16 | 1998-09-16 | A new composition |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0103544A2 true HUP0103544A2 (hu) | 2002-05-29 |
HUP0103544A3 HUP0103544A3 (en) | 2003-12-29 |
Family
ID=20412627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103544A HUP0103544A3 (en) | 1998-09-16 | 1999-09-13 | Pharmaceutical composition containing (r)-3-n,n-dicyklobutylamino-8-fluoro-3,4-dihydro-2h-1-benzopyran-5-carboxamide hidrogen-(2r,3r)tartarate monohydrate and paroxetin and process for its preparation |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1128825A1 (hu) |
JP (1) | JP2002524508A (hu) |
KR (1) | KR20010099647A (hu) |
CN (1) | CN1317964A (hu) |
AR (1) | AR021808A1 (hu) |
AU (1) | AU6378099A (hu) |
BR (1) | BR9913748A (hu) |
CA (1) | CA2342341A1 (hu) |
CZ (1) | CZ2001961A3 (hu) |
EE (1) | EE200100157A (hu) |
HU (1) | HUP0103544A3 (hu) |
ID (1) | ID28785A (hu) |
IL (1) | IL141519A0 (hu) |
IS (1) | IS5879A (hu) |
NO (1) | NO20011312L (hu) |
PL (1) | PL346763A1 (hu) |
SE (1) | SE9803156D0 (hu) |
SK (1) | SK3262001A3 (hu) |
TR (1) | TR200100779T2 (hu) |
WO (1) | WO2000015218A1 (hu) |
ZA (1) | ZA200101946B (hu) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2425638C (en) | 2000-10-13 | 2011-04-05 | Neurosearch A/S | Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance |
WO2006093192A1 (ja) * | 2005-03-04 | 2006-09-08 | Tokyo Medical And Dental University | 覚醒剤精神病及び統合失調症の再発防止治療薬 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
-
1998
- 1998-09-16 SE SE9803156A patent/SE9803156D0/xx unknown
-
1999
- 1999-09-13 CZ CZ2001961A patent/CZ2001961A3/cs unknown
- 1999-09-13 AU AU63780/99A patent/AU6378099A/en not_active Abandoned
- 1999-09-13 PL PL99346763A patent/PL346763A1/xx unknown
- 1999-09-13 KR KR1020017003337A patent/KR20010099647A/ko not_active Application Discontinuation
- 1999-09-13 IL IL14151999A patent/IL141519A0/xx unknown
- 1999-09-13 CN CN99811010A patent/CN1317964A/zh active Pending
- 1999-09-13 TR TR2001/00779T patent/TR200100779T2/xx unknown
- 1999-09-13 HU HU0103544A patent/HUP0103544A3/hu unknown
- 1999-09-13 WO PCT/SE1999/001597 patent/WO2000015218A1/en not_active Application Discontinuation
- 1999-09-13 ID IDW20010581A patent/ID28785A/id unknown
- 1999-09-13 EE EEP200100157A patent/EE200100157A/xx unknown
- 1999-09-13 SK SK326-2001A patent/SK3262001A3/sk unknown
- 1999-09-13 BR BR9913748-8A patent/BR9913748A/pt not_active Application Discontinuation
- 1999-09-13 EP EP99951319A patent/EP1128825A1/en not_active Withdrawn
- 1999-09-13 JP JP2000569802A patent/JP2002524508A/ja active Pending
- 1999-09-13 CA CA002342341A patent/CA2342341A1/en not_active Abandoned
- 1999-09-15 AR ARP990104626A patent/AR021808A1/es not_active Application Discontinuation
-
2001
- 2001-03-07 IS IS5879A patent/IS5879A/is unknown
- 2001-03-08 ZA ZA200101946A patent/ZA200101946B/en unknown
- 2001-03-15 NO NO20011312A patent/NO20011312L/no unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200101946B (en) | 2002-06-10 |
IL141519A0 (en) | 2002-03-10 |
WO2000015218A1 (en) | 2000-03-23 |
NO20011312D0 (no) | 2001-03-15 |
HUP0103544A3 (en) | 2003-12-29 |
EE200100157A (et) | 2002-08-15 |
PL346763A1 (en) | 2002-02-25 |
AR021808A1 (es) | 2002-08-07 |
JP2002524508A (ja) | 2002-08-06 |
NO20011312L (no) | 2001-05-16 |
ID28785A (id) | 2001-07-05 |
CZ2001961A3 (cs) | 2001-08-15 |
CN1317964A (zh) | 2001-10-17 |
TR200100779T2 (tr) | 2001-10-22 |
IS5879A (is) | 2001-03-07 |
KR20010099647A (ko) | 2001-11-09 |
SE9803156D0 (sv) | 1998-09-16 |
BR9913748A (pt) | 2001-07-10 |
AU6378099A (en) | 2000-04-03 |
EP1128825A1 (en) | 2001-09-05 |
SK3262001A3 (en) | 2001-08-06 |
CA2342341A1 (en) | 2000-03-23 |
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