HUP0102926A2 - Karnitint és inozit-foszfátot tartalmazó, táplálékkiegészítőként vagy gyógyszerként alkalmazható készítmény - Google Patents
Karnitint és inozit-foszfátot tartalmazó, táplálékkiegészítőként vagy gyógyszerként alkalmazható készítményInfo
- Publication number
- HUP0102926A2 HUP0102926A2 HU0102926A HUP0102926A HUP0102926A2 HU P0102926 A2 HUP0102926 A2 HU P0102926A2 HU 0102926 A HU0102926 A HU 0102926A HU P0102926 A HUP0102926 A HU P0102926A HU P0102926 A2 HUP0102926 A2 HU P0102926A2
- Authority
- HU
- Hungary
- Prior art keywords
- carnitine
- inositol phosphate
- drug
- containing composition
- dietary supplement
- Prior art date
Links
- INAPMGSXUVUWAF-GCVPSNMTSA-N [(2r,3s,5r,6r)-2,3,4,5,6-pentahydroxycyclohexyl] dihydrogen phosphate Chemical compound OC1[C@H](O)[C@@H](O)C(OP(O)(O)=O)[C@H](O)[C@@H]1O INAPMGSXUVUWAF-GCVPSNMTSA-N 0.000 title abstract 2
- 235000015872 dietary supplement Nutrition 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000002950 deficient Effects 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 abstract 1
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229940068041 phytic acid Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A találmány kombinált készítményre vonatkozik, mely (a) propionil-L-karnitint vagy gyógyászatilag elfogadható sóját; és (b) inozit-foszfátot (különösen inozit-hexafoszfátot) tartalmaz. A készítmény alkalmas kardiovaszkuláris ésneurocerebrális rendellenességek, különféle oxigénhiányos szövetek,energiahiányos izmok, gyulladásos típusú rendellenességek, a vérkoaguláció miatti megváltozásai, például trombózis és szövetburjánzásiformák megelőzésére és/vagy kezelésére. A találmány szerintikészítmény lehet táplálékkiegészítő vagy valódi gyógyszer formájában akezelendő személy állapotától függően. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999RM000248A IT1306133B1 (it) | 1999-04-22 | 1999-04-22 | Composizione comprendente una carnitina ed un inositolfosfato, utilequale integratore dietetico o medicamento. |
| PCT/IT2000/000158 WO2000064426A2 (en) | 1999-04-22 | 2000-04-19 | Carnitine and inositol phosphate-containing composition useful as dietary supplement or drug |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0102926A2 true HUP0102926A2 (hu) | 2002-03-28 |
| HUP0102926A3 HUP0102926A3 (en) | 2002-12-28 |
| HU227357B1 HU227357B1 (en) | 2011-04-28 |
Family
ID=11406708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0102926A HU227357B1 (en) | 1999-04-22 | 2000-04-19 | Carnitine and inositol phosphate-containing composition useful as dietary supplement or drug |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6565876B1 (hu) |
| EP (1) | EP1119363B1 (hu) |
| JP (1) | JP2002542282A (hu) |
| KR (1) | KR20010053023A (hu) |
| CN (1) | CN1359295A (hu) |
| AR (1) | AR023391A1 (hu) |
| AT (1) | ATE299370T1 (hu) |
| AU (1) | AU776591B2 (hu) |
| BR (1) | BR0006076A (hu) |
| CA (1) | CA2335015C (hu) |
| DE (1) | DE60021247T2 (hu) |
| DK (1) | DK1119363T3 (hu) |
| EE (1) | EE200000742A (hu) |
| ES (1) | ES2243254T3 (hu) |
| HU (1) | HU227357B1 (hu) |
| IL (1) | IL140164A0 (hu) |
| IS (1) | IS5763A (hu) |
| IT (1) | IT1306133B1 (hu) |
| NO (1) | NO20006429L (hu) |
| PL (1) | PL197885B1 (hu) |
| PT (1) | PT1119363E (hu) |
| SI (1) | SI1119363T1 (hu) |
| SK (1) | SK19322000A3 (hu) |
| TN (1) | TNSN00083A1 (hu) |
| TR (1) | TR200003737T1 (hu) |
| WO (1) | WO2000064426A2 (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1316997B1 (it) * | 2000-03-02 | 2003-05-26 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento di vasculopatie,che comprende propionil l-carnitina e coenzima q10. |
| DE10032964B4 (de) * | 2000-07-06 | 2017-10-12 | Beiersdorf Ag | Verwendung von Kreatin in kosmetischen oder dermatologischen Zubereitungen |
| DE10129502A1 (de) * | 2001-06-19 | 2003-01-09 | Beiersdorf Ag | Verwendung von Carnitin und/oder einem oder mehreren Acyl-Carnitinen zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Steigerung der Ceramidbiosynthese |
| US8173618B2 (en) * | 2003-07-25 | 2012-05-08 | University Of Massachusetts | Formulations for reducing neuronal degeneration |
| US20090169585A1 (en) * | 2003-10-23 | 2009-07-02 | Resveratrol Partners, Llc | Resveratrol-Containing Compositions And Their Use In Modulating Gene Product Concentration Or Activity |
| US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
| DK1863495T3 (en) * | 2005-03-18 | 2015-04-20 | Normoxys Inc | CALCIUM AND SODIUM SALT OF MYO-INOSITOL 1.6: 2,3: 4,5 TRIPYROPHOSPHATE FOR CANCER TREATMENT |
| ES2280136B1 (es) * | 2006-02-17 | 2008-08-16 | Universitat De Les Illes Balears | Asociacion a dosis fija de fitato y zinc. |
| JP5281268B2 (ja) * | 2007-10-31 | 2013-09-04 | 花王株式会社 | 筋力向上剤 |
| US8597640B2 (en) * | 2007-10-31 | 2013-12-03 | University Of Massachusetts Lowell | Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging |
| AU2009315771A1 (en) * | 2008-11-11 | 2010-05-20 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Compound useful for treating cellulite |
| ES2670836T3 (es) | 2010-06-16 | 2018-06-01 | Alfasigma S.P.A. | Acetil-carnitina para uso en un método para incrementar la neurogénesis en el tejido neuronal |
| ES2495666B1 (es) * | 2013-03-15 | 2015-08-10 | Laboratoris Sanifit, S.L. | Uso de derivados con enlaces c-o-p en pacientes con fallo renal |
| KR102141971B1 (ko) * | 2018-11-12 | 2020-08-06 | 주식회사 노암 | 항암용 조성물 |
| US20220226286A1 (en) * | 2019-05-23 | 2022-07-21 | Ekyj Consulting Ii, Llc | Compositions and methods for the treatment and mitigation of alcohol-induced skin flushing |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5626849A (en) * | 1995-06-07 | 1997-05-06 | Reliv International, Inc. | Weight loss composition for burning and reducing synthesis of fats |
| JP2001511153A (ja) * | 1997-02-04 | 2001-08-07 | ブイ． コスバブ，ジョン | 血管変性性疾患の予防および処置のための組成物および方法 |
| IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
| US5904924A (en) * | 1997-11-04 | 1999-05-18 | Oncologics, Inc. | Green nutritional powder composition |
-
1999
- 1999-04-22 IT IT1999RM000248A patent/IT1306133B1/it active
-
2000
- 2000-04-05 AR ARP000101562A patent/AR023391A1/es unknown
- 2000-04-19 WO PCT/IT2000/000158 patent/WO2000064426A2/en active IP Right Grant
- 2000-04-19 AT AT00922866T patent/ATE299370T1/de active
- 2000-04-19 US US09/720,099 patent/US6565876B1/en not_active Expired - Lifetime
- 2000-04-19 JP JP2000613417A patent/JP2002542282A/ja active Pending
- 2000-04-19 EP EP00922866A patent/EP1119363B1/en not_active Expired - Lifetime
- 2000-04-19 SI SI200030711T patent/SI1119363T1/xx unknown
- 2000-04-19 KR KR1020007014435A patent/KR20010053023A/ko not_active Application Discontinuation
- 2000-04-19 CN CN00800654A patent/CN1359295A/zh active Pending
- 2000-04-19 CA CA002335015A patent/CA2335015C/en not_active Expired - Lifetime
- 2000-04-19 AU AU43135/00A patent/AU776591B2/en not_active Ceased
- 2000-04-19 BR BR0006076-3A patent/BR0006076A/pt not_active Application Discontinuation
- 2000-04-19 TR TR2000/03737T patent/TR200003737T1/xx unknown
- 2000-04-19 PT PT00922866T patent/PT1119363E/pt unknown
- 2000-04-19 HU HU0102926A patent/HU227357B1/hu not_active IP Right Cessation
- 2000-04-19 EE EEP200000742A patent/EE200000742A/xx unknown
- 2000-04-19 ES ES00922866T patent/ES2243254T3/es not_active Expired - Lifetime
- 2000-04-19 IL IL14016400A patent/IL140164A0/xx unknown
- 2000-04-19 SK SK1932-2000A patent/SK19322000A3/sk unknown
- 2000-04-19 DK DK00922866T patent/DK1119363T3/da active
- 2000-04-19 PL PL346160A patent/PL197885B1/pl unknown
- 2000-04-19 DE DE60021247T patent/DE60021247T2/de not_active Expired - Lifetime
- 2000-04-20 TN TNTNSN00083A patent/TNSN00083A1/fr unknown
- 2000-12-08 IS IS5763A patent/IS5763A/is unknown
- 2000-12-15 NO NO20006429A patent/NO20006429L/no not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P, IT Free format text: FORMER OWNER(S): SIGMA-TAU HEALTHSCIENCE S.P.A., IT |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |