HUP0102728A2 - Methods and transdermal compositions for pain relief - Google Patents
Methods and transdermal compositions for pain reliefInfo
- Publication number
- HUP0102728A2 HUP0102728A2 HU0102728A HUP0102728A HUP0102728A2 HU P0102728 A2 HUP0102728 A2 HU P0102728A2 HU 0102728 A HU0102728 A HU 0102728A HU P0102728 A HUP0102728 A HU P0102728A HU P0102728 A2 HUP0102728 A2 HU P0102728A2
- Authority
- HU
- Hungary
- Prior art keywords
- methods
- pain relief
- transdermal compositions
- pain
- patients
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 150000001412 amines Chemical class 0.000 abstract 2
- 230000002051 biphasic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A találmány tárgya egy transzdermális készítmény a betegek fájdalmánakkezelésére, azzal jellemezve, hogy (a) egy kétfázisú oldékonyságú aminbetegek fájdalmának kezelésére hatásos mennyiségét; és (b) az amintranszdermális bevitelére alkalmas, gyógyszerészetileg elfogadhatóvivőanyagot tartalmaz. ÓThe subject of the invention is a transdermal preparation for the treatment of pain in patients, characterized by (a) an effective amount of a biphasic soluble amine for the treatment of pain in patients; and (b) contains a pharmaceutically acceptable carrier suitable for transdermal administration of the amine. HE
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/106,684 US6290986B1 (en) | 1996-10-24 | 1998-06-29 | Method and composition for transdermal administration of pharmacologic agents |
US12290399P | 1999-03-05 | 1999-03-05 | |
PCT/US1999/014653 WO2000000120A1 (en) | 1998-06-29 | 1999-06-29 | Methods and transdermal compositions for pain relief |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0102728A2 true HUP0102728A2 (en) | 2002-03-28 |
HUP0102728A3 HUP0102728A3 (en) | 2002-12-28 |
Family
ID=26803907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102728A HUP0102728A3 (en) | 1998-06-29 | 1999-06-29 | Methods and transdermal compositions for pain relief |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1093348A4 (en) |
JP (1) | JP2002519310A (en) |
KR (1) | KR20010078754A (en) |
CN (1) | CN1331576A (en) |
AU (1) | AU4841599A (en) |
BG (1) | BG105175A (en) |
BR (1) | BR9912508A (en) |
CA (1) | CA2335837A1 (en) |
HR (1) | HRP20000905A2 (en) |
HU (1) | HUP0102728A3 (en) |
ID (1) | ID28213A (en) |
IL (1) | IL140420A0 (en) |
MX (1) | MXPA00012767A (en) |
NO (1) | NO20006604L (en) |
PL (1) | PL345216A1 (en) |
SK (1) | SK20012000A3 (en) |
TR (1) | TR200003801T2 (en) |
WO (1) | WO2000000120A1 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6572880B2 (en) * | 1996-10-24 | 2003-06-03 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
ATE289295T1 (en) | 1997-04-22 | 2005-03-15 | Euro Celtique Sa | THE USE OF SEMICARBAZONES AND THIOSEMICARBAZONES SUBSTITUTED BY CARBOCYCLIC AND HETEROCYCLIC MATERIALS AS SODIUM CHANNEL BLOCKERS |
EP1629843A3 (en) * | 1999-07-01 | 2006-03-15 | Pharmacia & Upjohn Company LLC | Reboxetine for treating chronic fatigue syndrome |
ATE305307T1 (en) | 1999-07-01 | 2005-10-15 | Pharmacia & Upjohn Co Llc | REBOXETINE FOR THE TREATMENT OF MIGRAINE HEADACHE |
WO2001041732A1 (en) * | 1999-12-06 | 2001-06-14 | Gore Stanley L | Compositions and methods for intranasal delivery of active agents to the brain |
IN191512B (en) * | 2000-01-21 | 2003-12-06 | Panacea Biotech | |
DE10032132A1 (en) * | 2000-07-01 | 2002-01-17 | Lohmann Therapie Syst Lts | Dermal therapeutic system containing non-steroidal anti-inflammatory drugs with selective COX-2 inhibition |
DE10042412B4 (en) * | 2000-08-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | Transceiver for bus subscriber of bus system of building system engineering, has two wires, where microcontroller is connected with receiver unit over connection on one hand, which is connected to two wires of bus system |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
CN101797221B (en) | 2002-12-13 | 2013-06-12 | 杜雷科特公司 | Oral drug delivery system comprising high viscosity liquid carrier materials |
JP2005154368A (en) * | 2003-11-27 | 2005-06-16 | Teikoku Seiyaku Co Ltd | Analgesic agent for neuropathic pain containing disopyramide |
JP4807721B2 (en) * | 2004-01-29 | 2011-11-02 | 株式会社 メドレックス | Anti-inflammatory analgesic topical |
SI2767292T1 (en) | 2004-09-17 | 2017-01-31 | Durect Corporation | Sustained Local Anesthetic Composition Containing SAIB |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
JP2007308403A (en) * | 2006-05-17 | 2007-11-29 | Kenji Yoshida | Skin care preparation |
KR100880748B1 (en) * | 2006-08-29 | 2009-02-02 | 정헌택 | Pharmaceutical composition containing demethoxycurcumin to prevent restenosis |
ES2388355T3 (en) | 2006-11-03 | 2012-10-11 | Durect Corporation | Transdemic delivery systems comprising bupivacaine |
US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
AU2008347158B8 (en) | 2007-12-06 | 2013-08-22 | Durect Corporation | Oral pharmaceutical dosage forms |
US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
JP5826742B2 (en) * | 2009-05-07 | 2015-12-02 | ドンコック ファーマシューティカル カンパニー リミテッド | Pharmaceutical composition for preventing or treating nerve damage and disease |
US8491927B2 (en) * | 2009-12-02 | 2013-07-23 | Nimble Epitech, Llc | Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor |
WO2014144975A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
WO2015123272A1 (en) * | 2014-02-11 | 2015-08-20 | Dr. Reddy's Laboratories Ltd. | Parenteral compositions of celecoxib |
BR112021007877A2 (en) | 2018-10-26 | 2021-08-03 | Viramal Limited | mucoadhesive gel composition |
EP3659583B1 (en) | 2018-11-30 | 2023-06-07 | Viramal Limited | A method of preparing a gelling agent, the gelling agent obtained thereby, and the use of said gelling agent |
CN115666621A (en) | 2020-01-13 | 2023-01-31 | 度勒科特公司 | Sustained release drug delivery systems with reduced impurities and related methods |
FR3108841B1 (en) * | 2020-04-06 | 2023-11-03 | Algotherapeutix | TOPICAL PHARMACEUTICAL COMPOSITION IN AQUEOUS GEL FORM COMPRISING AT LEAST AMITRIPTYLINE |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4395420A (en) * | 1981-12-09 | 1983-07-26 | Bernstein Joel E | Method and composition for treating pruritis |
SI9300468A (en) * | 1992-10-14 | 1994-06-30 | Hoffmann La Roche | Injectable composition for the sustained release of biologically active compounds |
GB9315856D0 (en) * | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
US5654337A (en) * | 1995-03-24 | 1997-08-05 | II William Scott Snyder | Topical formulation for local delivery of a pharmaceutically active agent |
US5837289A (en) * | 1996-07-23 | 1998-11-17 | Grasela; John C. | Transdermal delivery of medications using a combination of penetration enhancers |
US5885597A (en) * | 1997-10-01 | 1999-03-23 | Medical Research Industries,Inc. | Topical composition for the relief of pain |
-
1999
- 1999-06-29 PL PL99345216A patent/PL345216A1/en unknown
- 1999-06-29 HU HU0102728A patent/HUP0102728A3/en unknown
- 1999-06-29 ID IDW20010231A patent/ID28213A/en unknown
- 1999-06-29 EP EP99932017A patent/EP1093348A4/en not_active Withdrawn
- 1999-06-29 JP JP2000556706A patent/JP2002519310A/en active Pending
- 1999-06-29 CA CA002335837A patent/CA2335837A1/en not_active Abandoned
- 1999-06-29 SK SK2001-2000A patent/SK20012000A3/en unknown
- 1999-06-29 AU AU48415/99A patent/AU4841599A/en not_active Abandoned
- 1999-06-29 WO PCT/US1999/014653 patent/WO2000000120A1/en not_active Application Discontinuation
- 1999-06-29 KR KR1020007014985A patent/KR20010078754A/en not_active Application Discontinuation
- 1999-06-29 MX MXPA00012767A patent/MXPA00012767A/en unknown
- 1999-06-29 CN CN99810055A patent/CN1331576A/en active Pending
- 1999-06-29 IL IL14042099A patent/IL140420A0/en unknown
- 1999-06-29 TR TR2000/03801T patent/TR200003801T2/en unknown
- 1999-06-29 BR BR9912508-0A patent/BR9912508A/en not_active Application Discontinuation
-
2000
- 2000-12-22 NO NO20006604A patent/NO20006604L/en not_active Application Discontinuation
- 2000-12-28 HR HR20000905A patent/HRP20000905A2/en not_active Application Discontinuation
-
2001
- 2001-01-24 BG BG105175A patent/BG105175A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2000000120A9 (en) | 2000-03-30 |
BR9912508A (en) | 2001-05-02 |
WO2000000120A1 (en) | 2000-01-06 |
CN1331576A (en) | 2002-01-16 |
EP1093348A1 (en) | 2001-04-25 |
BG105175A (en) | 2001-11-30 |
CA2335837A1 (en) | 2000-01-06 |
HUP0102728A3 (en) | 2002-12-28 |
KR20010078754A (en) | 2001-08-21 |
AU4841599A (en) | 2000-01-17 |
IL140420A0 (en) | 2002-02-10 |
HRP20000905A2 (en) | 2001-08-31 |
JP2002519310A (en) | 2002-07-02 |
EP1093348A4 (en) | 2003-07-16 |
TR200003801T2 (en) | 2001-06-21 |
ID28213A (en) | 2001-05-10 |
NO20006604L (en) | 2001-02-28 |
MXPA00012767A (en) | 2002-08-09 |
NO20006604D0 (en) | 2000-12-22 |
PL345216A1 (en) | 2001-12-03 |
SK20012000A3 (en) | 2001-08-06 |
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