HUP0101311A3 - 3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno [2,3-d]pyrimidine derivatives, their preparation and use as 5ht antagonists - Google Patents

3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno [2,3-d]pyrimidine derivatives, their preparation and use as 5ht antagonists

Info

Publication number
HUP0101311A3
HUP0101311A3 HU0101311A HUP0101311A HUP0101311A3 HU P0101311 A3 HUP0101311 A3 HU P0101311A3 HU 0101311 A HU0101311 A HU 0101311A HU P0101311 A HUP0101311 A HU P0101311A HU P0101311 A3 HUP0101311 A3 HU P0101311A3
Authority
HU
Hungary
Prior art keywords
thieno
pyrrolo
tetrahydro
antagonists
substituted
Prior art date
Application number
HU0101311A
Other languages
English (en)
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0101311A1 publication Critical patent/HUP0101311A1/hu
Publication of HUP0101311A3 publication Critical patent/HUP0101311A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU0101311A 1997-08-08 1998-07-23 3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno [2,3-d]pyrimidine derivatives, their preparation and use as 5ht antagonists HUP0101311A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19734444A DE19734444A1 (de) 1997-08-08 1997-08-08 3-Substituierte 3,4,5,7-Tetrahydro-pyrrolo(3',4':4,5) thieno (2,3-d) pyrimidin-Derivate, ihre Herstellung und Verwendung
PCT/EP1998/004633 WO1999007711A1 (de) 1997-08-08 1998-07-23 3-substituierte 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5] thieno[2,3-d] pyrimidin-derivate, ihre herstellung und verwendung als 5ht-antagonisten

Publications (2)

Publication Number Publication Date
HUP0101311A1 HUP0101311A1 (hu) 2001-09-28
HUP0101311A3 true HUP0101311A3 (en) 2002-10-28

Family

ID=7838438

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101311A HUP0101311A3 (en) 1997-08-08 1998-07-23 3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno [2,3-d]pyrimidine derivatives, their preparation and use as 5ht antagonists

Country Status (25)

Country Link
US (1) US6355647B1 (hu)
EP (1) EP1003752A1 (hu)
JP (1) JP2001512734A (hu)
KR (1) KR20010022658A (hu)
CN (1) CN1267303A (hu)
AR (1) AR016594A1 (hu)
AU (1) AU749539B2 (hu)
BG (1) BG104151A (hu)
BR (1) BR9811091A (hu)
CA (1) CA2300391A1 (hu)
CO (1) CO4960665A1 (hu)
CZ (1) CZ290678B6 (hu)
DE (1) DE19734444A1 (hu)
HR (1) HRP980435A2 (hu)
HU (1) HUP0101311A3 (hu)
ID (1) ID24222A (hu)
IL (1) IL134161A0 (hu)
NO (1) NO20000605D0 (hu)
NZ (1) NZ502657A (hu)
PL (1) PL340726A1 (hu)
SK (1) SK1052000A3 (hu)
TR (1) TR200000371T2 (hu)
TW (1) TW513435B (hu)
WO (1) WO1999007711A1 (hu)
ZA (1) ZA987114B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0216027D0 (en) * 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
US20040048874A1 (en) * 2001-05-22 2004-03-11 Bardsley Hazel Judith New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
CN100353946C (zh) * 2003-01-13 2007-12-12 戴诺吉药品有限公司 治疗功能性肠病的方法
MXPA05007379A (es) * 2003-01-13 2006-02-10 Dynogen Pharmaceuticals Inc Metodo para tratar nauseas, vomito, esfuerzo por vomitar o cualquier combinacion de los mismos.
ES2290741T3 (es) * 2003-04-04 2008-02-16 Dynogen Pharmaceuticals Inc. Metodo de tratamiento de trastornos del tracto urinario inferior.
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
US7375814B2 (en) * 2005-03-11 2008-05-20 Sandia Corporation Natural gas leak mapper
WO2006105117A2 (en) * 2005-03-28 2006-10-05 Dynogen Pharmaceuticals, Inc. Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
WO2020183011A1 (en) 2019-03-14 2020-09-17 Institut Curie Htr1d inhibitors and uses thereof in the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001130A (en) 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) * 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents
DE19636769A1 (de) * 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
BR9811091A (pt) 2000-09-12
EP1003752A1 (de) 2000-05-31
ID24222A (id) 2000-07-13
BG104151A (bg) 2000-10-31
NO20000605L (no) 2000-02-07
DE19734444A1 (de) 1999-02-11
ZA987114B (en) 2000-02-07
KR20010022658A (ko) 2001-03-26
CA2300391A1 (en) 1999-02-18
CZ2000462A3 (cs) 2000-05-17
SK1052000A3 (en) 2000-08-14
AU749539B2 (en) 2002-06-27
PL340726A1 (en) 2001-02-26
CN1267303A (zh) 2000-09-20
HUP0101311A1 (hu) 2001-09-28
NZ502657A (en) 2001-06-29
AU9068398A (en) 1999-03-01
JP2001512734A (ja) 2001-08-28
TW513435B (en) 2002-12-11
AR016594A1 (es) 2001-07-25
TR200000371T2 (tr) 2000-11-21
WO1999007711A1 (de) 1999-02-18
US6355647B1 (en) 2002-03-12
NO20000605D0 (no) 2000-02-07
IL134161A0 (en) 2001-04-30
HRP980435A2 (en) 1999-04-30
CO4960665A1 (es) 2000-09-25
CZ290678B6 (cs) 2002-09-11

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