HUP0101191A3 - Deprotection and recrystallization processes - Google Patents
Deprotection and recrystallization processesInfo
- Publication number
- HUP0101191A3 HUP0101191A3 HU0101191A HUP0101191A HUP0101191A3 HU P0101191 A3 HUP0101191 A3 HU P0101191A3 HU 0101191 A HU0101191 A HU 0101191A HU P0101191 A HUP0101191 A HU P0101191A HU P0101191 A3 HUP0101191 A3 HU P0101191A3
- Authority
- HU
- Hungary
- Prior art keywords
- deprotection
- recrystallization processes
- recrystallization
- processes
- Prior art date
Links
- 238000010511 deprotection reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000001953 recrystallisation Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7057398P | 1998-01-06 | 1998-01-06 | |
PCT/US1998/026443 WO1999035145A1 (en) | 1998-01-06 | 1998-12-11 | Deprotection and recrystallization processes |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0101191A2 HUP0101191A2 (hu) | 2001-09-28 |
HUP0101191A3 true HUP0101191A3 (en) | 2002-06-28 |
Family
ID=22096136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0101191A HUP0101191A3 (en) | 1998-01-06 | 1998-12-11 | Deprotection and recrystallization processes |
Country Status (10)
Country | Link |
---|---|
US (3) | US6340752B1 (hu) |
EP (1) | EP1051419A4 (hu) |
JP (1) | JP2002500224A (hu) |
KR (1) | KR20010085182A (hu) |
AU (1) | AU745379B2 (hu) |
CA (1) | CA2317718A1 (hu) |
HU (1) | HUP0101191A3 (hu) |
IL (1) | IL136361A0 (hu) |
TW (1) | TW515800B (hu) |
WO (1) | WO1999035145A1 (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010071895A (ko) | 1998-07-15 | 2001-07-31 | 스티븐 비. 데이비스 | 신규 디옥솔란을 통한 (s)-2-아미노-6,6-디메톡시헥산산메틸 에스테르의 제조 방법 |
US6162913A (en) * | 1998-07-15 | 2000-12-19 | Bristol-Myers Squibb Co. | Preparation of [4S-(4α,7α,10aβ)]-4-amino-octahydro-5-oxo-7H-pyrido[2,1 -b] [1,3]thiazepine-7-carboxylic acid, methyl ester and salts thereof via novel disulfides |
US6770640B1 (en) | 1998-12-31 | 2004-08-03 | Aventis Pharmaceuticals Inc. | 1-Carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of MMP-12 |
EP1235792A4 (en) * | 1999-07-29 | 2003-06-25 | Bristol Myers Squibb Co | PREPARATION OF 4S- (4-g (a), 7-g (a), 10A-g (b))] - 4-AMINO-OCTAHYDRO-5-OXO-7H-PYRIDO 2,1-B] 1,3 ] THIAZEPINE-7-CARBONIC ACID METHYL ESTER AND ITS SALTS VIA NEW DISULFIDES |
US6620600B2 (en) | 2000-09-15 | 2003-09-16 | Bristol-Myers Squibb Co. | Enzymatic resolution of aryl and thio-substituted acids |
WO2024103123A1 (en) * | 2022-11-17 | 2024-05-23 | Endothelium Scanning Nanotechnology Limited | The synthesis of omapatrilat |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5552397A (en) | 1992-05-18 | 1996-09-03 | E. R. Squibb & Sons, Inc. | Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase |
RU2124503C1 (ru) * | 1992-05-18 | 1999-01-10 | И.Р.Сквибб энд Санз, Инк. | Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция |
US5504080A (en) | 1992-10-28 | 1996-04-02 | Bristol-Myers Squibb Co. | Benzo-fused lactams |
US5508272A (en) * | 1993-06-15 | 1996-04-16 | Bristol-Myers Squibb Company | Compounds containing a fused bicycle ring and processes therefor |
US5362727A (en) | 1993-07-26 | 1994-11-08 | Bristol-Myers Squibb | Substituted azepino[2,1-a]isoquinoline compounds |
US5525723A (en) | 1993-11-18 | 1996-06-11 | Bristol-Myers Squibb Co. | Compounds containing a fused multiple ring lactam |
US5587375A (en) | 1995-02-17 | 1996-12-24 | Bristol-Myers Squibb Company | Azepinone compounds useful in the inhibition of ACE and NEP |
US5877313A (en) | 1995-05-17 | 1999-03-02 | Bristol-Myers Squibb | Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP |
US5635504A (en) | 1995-06-07 | 1997-06-03 | Bristol-Myers Squibb Co. | Diazepine containing dual action inhibitors |
US5650408A (en) | 1995-06-07 | 1997-07-22 | Karanewsky; Donald S. | Thiazolo benzazepine containing dual action inhibitors |
-
1998
- 1998-12-09 US US09/208,135 patent/US6340752B1/en not_active Expired - Fee Related
- 1998-12-11 WO PCT/US1998/026443 patent/WO1999035145A1/en not_active Application Discontinuation
- 1998-12-11 IL IL13636198A patent/IL136361A0/xx unknown
- 1998-12-11 EP EP98963113A patent/EP1051419A4/en not_active Withdrawn
- 1998-12-11 KR KR1020007007451A patent/KR20010085182A/ko not_active Application Discontinuation
- 1998-12-11 HU HU0101191A patent/HUP0101191A3/hu unknown
- 1998-12-11 CA CA002317718A patent/CA2317718A1/en not_active Abandoned
- 1998-12-11 AU AU18207/99A patent/AU745379B2/en not_active Ceased
- 1998-12-11 JP JP2000527544A patent/JP2002500224A/ja active Pending
- 1998-12-30 TW TW087121917A patent/TW515800B/zh not_active IP Right Cessation
-
2001
- 2001-11-16 US US09/993,872 patent/US6486315B2/en not_active Expired - Fee Related
- 2001-11-16 US US09/991,408 patent/US6444810B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2317718A1 (en) | 1999-07-15 |
KR20010085182A (ko) | 2001-09-07 |
WO1999035145A1 (en) | 1999-07-15 |
US20020086994A1 (en) | 2002-07-04 |
IL136361A0 (en) | 2001-06-14 |
US6486315B2 (en) | 2002-11-26 |
HUP0101191A2 (hu) | 2001-09-28 |
JP2002500224A (ja) | 2002-01-08 |
AU745379B2 (en) | 2002-03-21 |
TW515800B (en) | 2003-01-01 |
EP1051419A1 (en) | 2000-11-15 |
US20020086995A1 (en) | 2002-07-04 |
AU1820799A (en) | 1999-07-26 |
US6444810B1 (en) | 2002-09-03 |
US6340752B1 (en) | 2002-01-22 |
EP1051419A4 (en) | 2002-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |