HUP0004857A2 - T. variabilisból származó D-aminosav oxidáz promótere - Google Patents
T. variabilisból származó D-aminosav oxidáz promótereInfo
- Publication number
- HUP0004857A2 HUP0004857A2 HU0004857A HUP0004857A HUP0004857A2 HU P0004857 A2 HUP0004857 A2 HU P0004857A2 HU 0004857 A HU0004857 A HU 0004857A HU P0004857 A HUP0004857 A HU P0004857A HU P0004857 A2 HUP0004857 A2 HU P0004857A2
- Authority
- HU
- Hungary
- Prior art keywords
- promoter
- variabilis
- amino acid
- acid oxidase
- expression
- Prior art date
Links
- 108010003989 D-amino-acid oxidase Proteins 0.000 title abstract 2
- 241000047477 Thouarella variabilis Species 0.000 title abstract 2
- 102000004674 D-amino-acid oxidase Human genes 0.000 title 1
- 239000013598 vector Substances 0.000 abstract 3
- 239000013604 expression vector Substances 0.000 abstract 2
- 108700039691 Genetic Promoter Regions Proteins 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12N9/0024—D-Amino acid oxidase (1.4.3.3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A találmány tárgya T. variabilisből származó D-aminosav oxidáz génpromoterrégióját tartalmazó, izolált nukleinsav. Meghatározták apromoter szekvenciáját. A találmány tárgyát képezik olyan expressziós vektorok is, amelyeka találmány szerinti promotert tartalmazzák, különösen olyan vektorok,amelyek S. cerevisiaeben való expresszióra alkalmasak. A találmányszerinti előnyös expressziós vektorok az új promoterrel rendelkeznekS. cerevisiae szelektálható markertől szintézisiránnyal szembenelhelyezve. A vektor manipulálása ugyanezen, a promotert tartalmazóvetkorba klónozott, kívánt fehérje fokozott expressziójához vezet. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5074097P | 1997-06-25 | 1997-06-25 | |
PCT/US1998/011759 WO1998059037A1 (en) | 1997-06-25 | 1998-06-08 | D-amino acid oxidase promoter from t. variabilis |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0004857A2 true HUP0004857A2 (hu) | 2001-04-28 |
HUP0004857A3 HUP0004857A3 (en) | 2001-09-28 |
Family
ID=21967122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0004857A HUP0004857A3 (en) | 1997-06-25 | 1998-06-08 | D-amino acid oxidase promoter from t. variabilis |
Country Status (8)
Country | Link |
---|---|
US (1) | US6025159A (hu) |
EP (1) | EP0990023A4 (hu) |
JP (1) | JP2002505587A (hu) |
AU (1) | AU749453B2 (hu) |
CA (1) | CA2292844A1 (hu) |
HU (1) | HUP0004857A3 (hu) |
IL (2) | IL133259A0 (hu) |
WO (1) | WO1998059037A1 (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4830079B2 (ja) * | 2000-11-29 | 2011-12-07 | 国立感染症研究所長 | プロテアーゼ活性の測定方法 |
US7187286B2 (en) | 2004-03-19 | 2007-03-06 | Applera Corporation | Methods and systems for using RFID in biological field |
CA2705925C (en) * | 2007-12-19 | 2019-03-12 | Glycofi, Inc. | Yeast strains for protein production |
ES2811139T3 (es) * | 2015-04-03 | 2021-03-10 | Temasek Life Sciences Laboratory Ltd | Sistema de expresión génica inducible por D-aminoácido para Rhodosporidium y Rhodotorula |
CN111670072B (zh) | 2018-01-30 | 2023-10-27 | 生命技术公司 | 用于智能分子分析系统的工作流中的仪器、装置和消耗品 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE123303T1 (de) * | 1988-10-13 | 1995-06-15 | Fujisawa Pharmaceutical Co | D-aminosäureoxidase. |
DE69019967T2 (de) * | 1989-04-04 | 1996-02-22 | Biopure Corp | Enzymatisches verfahren zur herstellung von 7-aminocephalosporansäure. |
DE4133038A1 (de) * | 1991-10-07 | 1993-04-08 | Genentech Inc | Neue recombinante viren, deren verwendung und deren herstellung |
CA2100987C (en) * | 1992-07-27 | 1999-06-15 | Kaoru Furuya | A transformant capable of producing d-amino acid oxidase |
-
1998
- 1998-06-08 AU AU78235/98A patent/AU749453B2/en not_active Ceased
- 1998-06-08 JP JP50453199A patent/JP2002505587A/ja not_active Ceased
- 1998-06-08 HU HU0004857A patent/HUP0004857A3/hu unknown
- 1998-06-08 IL IL13325998A patent/IL133259A0/xx not_active IP Right Cessation
- 1998-06-08 EP EP98926385A patent/EP0990023A4/en not_active Withdrawn
- 1998-06-08 WO PCT/US1998/011759 patent/WO1998059037A1/en active IP Right Grant
- 1998-06-08 CA CA002292844A patent/CA2292844A1/en not_active Abandoned
- 1998-06-18 US US09/099,564 patent/US6025159A/en not_active Expired - Fee Related
-
1999
- 1999-12-01 IL IL133259A patent/IL133259A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU7823598A (en) | 1999-01-04 |
IL133259A (en) | 2006-06-11 |
WO1998059037A1 (en) | 1998-12-30 |
JP2002505587A (ja) | 2002-02-19 |
HUP0004857A3 (en) | 2001-09-28 |
US6025159A (en) | 2000-02-15 |
CA2292844A1 (en) | 1998-12-30 |
EP0990023A4 (en) | 2001-04-18 |
AU749453B2 (en) | 2002-06-27 |
EP0990023A1 (en) | 2000-04-05 |
IL133259A0 (en) | 2001-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |