HUP0003999A2 - Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them - Google Patents

Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them

Info

Publication number
HUP0003999A2
HUP0003999A2 HU0003999A HUP0003999A HUP0003999A2 HU P0003999 A2 HUP0003999 A2 HU P0003999A2 HU 0003999 A HU0003999 A HU 0003999A HU P0003999 A HUP0003999 A HU P0003999A HU P0003999 A2 HUP0003999 A2 HU P0003999A2
Authority
HU
Hungary
Prior art keywords
compounds
compositions containing
thiadiazine
fused
preparation
Prior art date
Application number
HU0003999A
Other languages
Hungarian (hu)
Inventor
Holger Claus Hansen
John Bondo Hansen
John Patrick Mogensen
Flemmig Elmedlund Nielsen
Tina Moller Tagmose
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP0003999A2 publication Critical patent/HUP0003999A2/en
Publication of HUP0003999A3 publication Critical patent/HUP0003999A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

A jelen találmány tárgyát 1,2,4-tiadiazin-származékok, az ezenvegyületek előállítására szolgáló eljárások, valamint az ezenvegyületeket tartalmazó összetételek képezik. A találmány tárgyátképezi továbbá ezen vegyületek alkalmazása gyógyszerek előállításánál,illetve terápiás célokra történő felhasználása. A találmány szerintivegyületek különösen alkalmasak például a központi idegrendszer, aszív- és érrendszer, a légzőszervek, az emésztőrendszer és ahormonrendszer betegségeinek, a vázizom csökkent vérkeringésével járóbetegségek, a koraszülés és a menstruációs zavarok, a kopaszságvalamint a vizelettartási nehézségek kezelésében. A találmány szerintielőnyös vegyületek tieno[3,2-e][1,2,4]-tiadiazin-1,1-dioxid-származékok. ÓThe subject of the present invention is 1,2,4-thiadiazine derivatives, processes for the production of these compounds, and compositions containing these compounds. The invention also covers the use of these compounds in the production of medicines, as well as their use for therapeutic purposes. The compounds according to the invention are particularly suitable, for example, in the treatment of diseases of the central nervous system, cardiovascular system, respiratory organs, digestive system and hormonal system, diseases associated with reduced blood circulation of the skeletal muscles, premature birth and menstrual disorders, baldness, as well as urinary retention difficulties. Preferred compounds according to the invention are thieno[3,2-e][1,2,4]-thiadiazine-1,1-dioxide derivatives. HE

HU0003999A 1997-07-16 1998-06-30 Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them HUP0003999A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK87297 1997-07-16
DK36898 1998-03-17
PCT/DK1998/000288 WO1999003861A1 (en) 1997-07-16 1998-06-30 Fused 1,2,4-thiadiazine derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
HUP0003999A2 true HUP0003999A2 (en) 2001-08-28
HUP0003999A3 HUP0003999A3 (en) 2003-03-28

Family

ID=26063863

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003999A HUP0003999A3 (en) 1997-07-16 1998-06-30 Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them

Country Status (13)

Country Link
EP (1) EP1000066A1 (en)
JP (1) JP2001510195A (en)
KR (1) KR20010021936A (en)
CN (1) CN1264384A (en)
AU (1) AU757693B2 (en)
BR (1) BR9810592A (en)
CA (1) CA2294830A1 (en)
HU (1) HUP0003999A3 (en)
IL (1) IL133604A0 (en)
NO (1) NO315470B1 (en)
PL (1) PL338013A1 (en)
RU (1) RU2215004C2 (en)
WO (1) WO1999003861A1 (en)

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