DE102010015123A1 - New benzylamidic diphenylazetidinone compounds, useful for treating lipid disorders, hyperlipidemia, atherosclerotic manifestations or insulin resistance, and for reducing serum cholesterol levels - Google Patents

New benzylamidic diphenylazetidinone compounds, useful for treating lipid disorders, hyperlipidemia, atherosclerotic manifestations or insulin resistance, and for reducing serum cholesterol levels

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Publication number
DE102010015123A1
DE102010015123A1 DE102010015123A DE102010015123A DE102010015123A1 DE 102010015123 A1 DE102010015123 A1 DE 102010015123A1 DE 102010015123 A DE102010015123 A DE 102010015123A DE 102010015123 A DE102010015123 A DE 102010015123A DE 102010015123 A1 DE102010015123 A1 DE 102010015123A1
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DE
Germany
Prior art keywords
wo
described
compound
formula
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102010015123A
Other languages
German (de)
Inventor
Dr. Heuer Huber
Dr. Holla Wolfgang
Dr. Jaehne Gerhard
Dr. Krone Volker
Dr. Riedel Jens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Priority to DE102010015123A priority Critical patent/DE102010015123A1/en
Publication of DE102010015123A1 publication Critical patent/DE102010015123A1/en
Application status is Withdrawn legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Abstract

Benzylamidic diphenylazetidinone compounds (I) and their salts, are new. Benzylamidic diphenylazetidinone compounds of formula (I) and their salts, are new. X : 1-30C, preferably 2-10C alkylene, which is one or more times, preferably 1-3 times substituted by OH. An independent claim is included for a medicament comprising (I) and at least one further active substance. [Image] ACTIVITY : Antilipemic; Antiarteriosclerotic; Antidiabetic. MECHANISM OF ACTION : None given.

Description