HUP0003681A1 - Pharmaceutical substance containing various vitamin k-dependent factors - Google Patents

Pharmaceutical substance containing various vitamin k-dependent factors

Info

Publication number
HUP0003681A1
HUP0003681A1 HU0003681A HUP0003681A HUP0003681A1 HU P0003681 A1 HUP0003681 A1 HU P0003681A1 HU 0003681 A HU0003681 A HU 0003681A HU P0003681 A HUP0003681 A HU P0003681A HU P0003681 A1 HUP0003681 A1 HU P0003681A1
Authority
HU
Hungary
Prior art keywords
containing various
substance containing
pharmaceutical substance
various vitamin
dependent factors
Prior art date
Application number
HU0003681A
Other languages
Hungarian (hu)
Inventor
Yendra Linnau
Hans-Peter Schwarz
Peter Turecek
Original Assignee
Baxter Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Aktiengesellschaft filed Critical Baxter Aktiengesellschaft
Publication of HUP0003681A1 publication Critical patent/HUP0003681A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány szeparált protrombinkomplex gyógyszerkészítményrevonatkozik, amely legalább két nagy tisztaságú K-vitamin-függő egyedivéralvadási faktort tartalmaz. ÓThe invention relates to a separated prothrombin complex pharmaceutical preparation, which contains at least two high-purity vitamin K-dependent individual coagulation factors. HE

HU0003681A 1997-09-19 1998-09-17 Pharmaceutical substance containing various vitamin k-dependent factors HUP0003681A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0159197A AT409334B (en) 1997-09-19 1997-09-19 PHARMACEUTICAL PREPARATION CONTAINING VITAMIN K-DEPENDENT INDIVIDUAL FACTORS

Publications (1)

Publication Number Publication Date
HUP0003681A1 true HUP0003681A1 (en) 2001-02-28

Family

ID=3516739

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003681A HUP0003681A1 (en) 1997-09-19 1998-09-17 Pharmaceutical substance containing various vitamin k-dependent factors

Country Status (10)

Country Link
EP (1) EP1015020A1 (en)
JP (1) JP2001517636A (en)
AT (1) AT409334B (en)
AU (1) AU743102B2 (en)
BR (1) BR9812222A (en)
CA (1) CA2304396A1 (en)
HU (1) HUP0003681A1 (en)
NO (1) NO20001415L (en)
SK (1) SK4022000A3 (en)
WO (1) WO1999015196A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60232017D1 (en) 2001-12-21 2009-05-28 Novo Nordisk Healthcare Ag LIQUID COMPOSITION OF FACTOR VII POLYPEPTIDES
CA2475738A1 (en) * 2002-03-08 2003-09-18 Eli Lilly And Company Activated protein c formulations
JP4648002B2 (en) 2002-06-21 2011-03-09 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト Stabilized solid composition of factor VII polypeptide
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
EP1628677B1 (en) 2003-05-23 2010-01-13 Novo Nordisk Health Care AG Protein stabilization in solution
ATE547114T1 (en) 2003-06-25 2012-03-15 Novo Nordisk Healthcare Ag LIQUID COMPOSITIONS OF FACTOR VII POLYPEPTIDES
AU2004264282B2 (en) 2003-08-14 2010-10-14 Novo Nordisk Health Care Ag Liquid, aqueous pharmaceutical composition of Factor VII polypeptides
PT2298287T (en) 2003-12-19 2018-07-23 Novo Nordisk Healthcare Ag Stabilised compositions of factor vii polypeptides
WO2006088741A2 (en) * 2005-02-16 2006-08-24 The Board Of Trustees Of The University Of Illinois Procoagulants based on metal-chelating lipids
JP2008531692A (en) 2005-03-04 2008-08-14 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ Modulators of the coagulation and fibrinolysis cascade
US8821861B2 (en) 2007-10-05 2014-09-02 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
JP5984676B2 (en) 2009-12-18 2016-09-06 シーエスエル、リミテッド Methods for purifying polypeptides
PL2624859T3 (en) 2010-10-06 2017-09-29 Medimmune Limited Factor ii alone or in combination with further factors for treatment of impaired haemostasis associated with dilutional coagulopathy
SG10201912497WA (en) * 2017-02-09 2020-02-27 Csl Behring Gmbh A blood coagulation factor replacement product for use in the treatment or prophylaxis of bleedings

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729822D0 (en) * 1987-12-22 1988-02-03 Central Blood Lab Authority Chemical process
IT1262899B (en) * 1992-03-27 1996-07-22 Sclavo Spa PROCESS FOR THE INSULATION OF FACTOR IX, FACTOR X AND FACTOR II HIGHLY PURIFIED FROM THE PROTROMBINIC COMPLEX OR HUMAN PLASMA
DE4342132C1 (en) * 1993-12-10 1994-11-03 Octapharma Ag Process for the preparation of virus-inactivated vitamin K-dependent plasma components, and protein C and protein S-containing compositions by membrane chromatography
DE4430205A1 (en) * 1994-08-26 1996-02-29 Behringwerke Ag Compositions suitable as antidotes for blood anticoagulants and their use
EP0796623B1 (en) * 1996-03-20 2005-05-25 Baxter Aktiengesellschaft Pharmaceutical preparation for the treatment of blood coagulation disorders

Also Published As

Publication number Publication date
AU743102B2 (en) 2002-01-17
AT409334B (en) 2002-07-25
EP1015020A1 (en) 2000-07-05
NO20001415D0 (en) 2000-03-17
BR9812222A (en) 2000-07-18
CA2304396A1 (en) 1999-04-01
SK4022000A3 (en) 2000-09-12
AU9244998A (en) 1999-04-12
NO20001415L (en) 2000-05-19
JP2001517636A (en) 2001-10-09
ATA159197A (en) 2001-12-15
WO1999015196A1 (en) 1999-04-01

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