HUP0003164A2 - A Helicobacter pylori FlgE polipeptidet tartalmazó vakcinakészítmények - Google Patents

A Helicobacter pylori FlgE polipeptidet tartalmazó vakcinakészítmények

Info

Publication number
HUP0003164A2
HUP0003164A2 HU0003164A HUP0003164A HUP0003164A2 HU P0003164 A2 HUP0003164 A2 HU P0003164A2 HU 0003164 A HU0003164 A HU 0003164A HU P0003164 A HUP0003164 A HU P0003164A HU P0003164 A2 HUP0003164 A2 HU P0003164A2
Authority
HU
Hungary
Prior art keywords
helicobacter pylori
vaccine compositions
polypeptide
subject
polypeptides
Prior art date
Application number
HU0003164A
Other languages
English (en)
Inventor
Thomas Berglindh
Björn Mellgárd
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of HUP0003164A2 publication Critical patent/HUP0003164A2/hu
Publication of HUP0003164A3 publication Critical patent/HUP0003164A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56922Campylobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/205Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgyát olyan polipeptidek és vakcinakészítmények képezik,amelyek Helicobacter pylori fertőzéssel szemben emlősben védőimmunválaszt indukálnak. A találmány tárgyát képezi továbbáHelicobacter pylori polipeptidek alkalmazása Helicobacter pylorifertőzések kezelésére, megelőzésére vagy diagnózisára szolgálókészítmények előállításában. Nevezett vakcinakészítmények H. pyloriFlgE polipeptid - vagy annak funkcionálisan ekvivalens antigenitástmegtartó módosított formája - mellett gyógyszerészetileg elfogadhatóhordozót, hígítószert vagy adott esetben adjuvánst - koleratoxint -tartalmaznak. Ó
HU0003164A 1997-06-12 1998-06-08 Vaccine compositions comprising the helicobacter pylori flge polypeptide HUP0003164A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9702242A SE9702242D0 (sv) 1997-06-12 1997-06-12 Vaccine compositions V

Publications (2)

Publication Number Publication Date
HUP0003164A2 true HUP0003164A2 (hu) 2000-12-28
HUP0003164A3 HUP0003164A3 (en) 2001-10-29

Family

ID=20407351

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003164A HUP0003164A3 (en) 1997-06-12 1998-06-08 Vaccine compositions comprising the helicobacter pylori flge polypeptide

Country Status (21)

Country Link
EP (1) EP1009764A1 (hu)
JP (1) JP2002507118A (hu)
KR (1) KR20010013699A (hu)
CN (1) CN1259960A (hu)
AR (1) AR012896A1 (hu)
AU (1) AU8048798A (hu)
BR (1) BR9810026A (hu)
CA (1) CA2293293A1 (hu)
EE (1) EE9900566A (hu)
HU (1) HUP0003164A3 (hu)
ID (1) ID23052A (hu)
IL (1) IL133144A0 (hu)
IS (1) IS5288A (hu)
NO (1) NO996132L (hu)
NZ (1) NZ501427A (hu)
PL (1) PL337503A1 (hu)
SE (1) SE9702242D0 (hu)
SK (1) SK173099A3 (hu)
TR (1) TR199903060T2 (hu)
WO (1) WO1998056816A1 (hu)
ZA (1) ZA984696B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784687A (zh) * 2015-04-27 2015-07-22 苏州大学附属第一医院 重组绿脓杆菌鞭毛钩蛋白FlgE的用途
CN113425717B (zh) * 2021-04-22 2023-06-16 成都欧林生物科技股份有限公司 一种提高口服幽门螺杆菌疫苗效力的药剂及其应用
CN116535472B (zh) * 2023-05-31 2024-04-30 四川大学华西医院 一种幽门螺杆菌重组蛋白抗原FlgK及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459041A (en) * 1988-02-18 1995-10-17 Enteric Research Laboratories, Inc. Campylobacter pylori antigens and uses thereof for detection of Campylobacter pylori infection
AR003125A1 (es) * 1995-06-01 1998-07-08 Astra Ab Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la

Also Published As

Publication number Publication date
HUP0003164A3 (en) 2001-10-29
ZA984696B (en) 1999-01-04
EP1009764A1 (en) 2000-06-21
BR9810026A (pt) 2000-09-19
CN1259960A (zh) 2000-07-12
NO996132D0 (no) 1999-12-10
IS5288A (is) 1999-12-08
WO1998056816A1 (en) 1998-12-17
IL133144A0 (en) 2001-03-19
KR20010013699A (ko) 2001-02-26
JP2002507118A (ja) 2002-03-05
SK173099A3 (en) 2000-06-12
NZ501427A (en) 2000-09-29
ID23052A (id) 2000-01-20
PL337503A1 (en) 2000-08-28
CA2293293A1 (en) 1998-12-17
EE9900566A (xx) 2000-06-15
SE9702242D0 (sv) 1997-06-12
AR012896A1 (es) 2000-11-22
AU8048798A (en) 1998-12-30
NO996132L (no) 2000-01-28
TR199903060T2 (xx) 2000-09-21

Similar Documents

Publication Publication Date Title
RU93058676A (ru) Оральное лечение геликобактерной инфекции
GEP20022695B (en) Moraxella Catarrhalis Outer Membrane Protein-106 Polypeptide, Gene Sequence and Uses Thereof
CY2570B1 (en) Compounds for immunotherapy and diagnosis of tuberculosis
MX9702955A (es) Vacuna y antitoxina para tratamiento y prevencion de enfermedad c. difficile.
WO1998053075A3 (en) Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
HUP0302965A2 (hu) Vakcina
WO1995006732A3 (en) Bacterial exported proteins and acellular vaccines based thereon
WO2000018351A3 (en) Aglyco products and methods of use
HUP9801266A2 (hu) Multimer, rekombináns ureázvakcina
AU7242796A (en) Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
NO912825L (no) Fremgangsmaate for fremstilling av kokonjugatvaksiner omfattende im munogent protein, hiv-beslektede peptider og anioniske grupper.
DE69533673D1 (de) Behandlung und prävention von helicobacter-infektionen
CA2022420A1 (en) Escherichia coli vaccine
IL97709A0 (en) Peptides and pharmaceutical compositions for treating multiple sclerosis containing the same
HUP9801223A2 (hu) Eljárás specifikus antigénekre adott antitest válasz fokozására interleukin-10-zel
EP0837692A4 (hu)
WO2001040473A3 (en) Pseudomonas aeruginosa antigens
HUP0003164A2 (hu) A Helicobacter pylori FlgE polipeptidet tartalmazó vakcinakészítmények
MX9801180A (es) Preparaciones antigenicas.
EP0955366A4 (en) ANTIGENIC PROTEIN FROM MALASSEZIA
SE9604322D0 (sv) Bacterial antigens and vaccine compositions II
HK1025220A1 (en) Novel saponin compositions and uses thereof
HUP0200162A2 (hu) Haemophilus somnus transzferrin-kötő fehérjék klónozása és expresszálása
WO2002004497A3 (en) Multiple antigenic peptides immunogenic against streptococcus pneumoniae
WO2002079240A3 (en) Intimins for the prevention or treatment of infections: i