HUP0000291A2 - Eljárás kriptoficinszármazékok előállítására - Google Patents

Eljárás kriptoficinszármazékok előállítására

Info

Publication number
HUP0000291A2
HUP0000291A2 HU0000291A HUP0000291A HUP0000291A2 HU P0000291 A2 HUP0000291 A2 HU P0000291A2 HU 0000291 A HU0000291 A HU 0000291A HU P0000291 A HUP0000291 A HU P0000291A HU P0000291 A2 HUP0000291 A2 HU P0000291A2
Authority
HU
Hungary
Prior art keywords
prepare
cryptophycin compounds
cryptophycin
compounds
chlorohydrin
Prior art date
Application number
HU0000291A
Other languages
English (en)
Inventor
Michael J. Martinelli
Eric D. Moher
Original Assignee
Eli Lilly And Co.,
University Of Hawaii
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co.,, University Of Hawaii, Wayne State University filed Critical Eli Lilly And Co.,
Publication of HUP0000291A2 publication Critical patent/HUP0000291A2/hu
Publication of HUP0000291A3 publication Critical patent/HUP0000291A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)

Abstract

A találmány tárgya eljárás kriptőficin-klór-hidrin diasztereőizőmerszármazékők előállítására egylépéses reakcióval, nőrmál fázisú,közönséges nyőmású krőmatőgráfiás elválasztással. ŕ
HU0000291A 1996-09-06 1997-09-05 Process to prepare cryptophycin compounds HUP0000291A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2543896P 1996-09-06 1996-09-06
PCT/US1997/015626 WO1998009988A1 (en) 1996-09-06 1997-09-05 Process to prepare pharmaceutical compounds

Publications (2)

Publication Number Publication Date
HUP0000291A2 true HUP0000291A2 (hu) 2000-09-28
HUP0000291A3 HUP0000291A3 (en) 2000-10-30

Family

ID=21826074

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000291A HUP0000291A3 (en) 1996-09-06 1997-09-05 Process to prepare cryptophycin compounds

Country Status (10)

Country Link
US (1) US6252064B1 (hu)
EP (1) EP0956295A1 (hu)
JP (1) JP2001500496A (hu)
KR (1) KR20010029474A (hu)
AU (1) AU4182197A (hu)
BR (1) BR9712805A (hu)
CA (1) CA2264245A1 (hu)
HU (1) HUP0000291A3 (hu)
IL (1) IL128497A0 (hu)
WO (1) WO1998009988A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0870506A1 (en) * 1997-04-11 1998-10-14 Eli Lilly And Company Compositions comprising a cryptophycin compound in combination with a synchronizing or activating agent for treating cancer
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2179490A1 (en) * 1993-12-21 1995-06-29 Trimurtulu Golakoti New cryptophycins
DE69633667T2 (de) * 1995-03-07 2006-03-02 University Of Hawaii, Honolulu Neue synthetische cryptophycine
YU10899A (sh) * 1996-08-30 2002-03-18 Eli Lilli And Company Farmaceutska jedinjenja
JP2001502297A (ja) * 1996-08-30 2001-02-20 イーライ・リリー・アンド・カンパニー 医薬用化合物

Also Published As

Publication number Publication date
CA2264245A1 (en) 1998-03-12
BR9712805A (pt) 1999-11-23
EP0956295A1 (en) 1999-11-17
EP0956295A4 (hu) 1999-12-22
JP2001500496A (ja) 2001-01-16
WO1998009988A1 (en) 1998-03-12
AU4182197A (en) 1998-03-26
HUP0000291A3 (en) 2000-10-30
US6252064B1 (en) 2001-06-26
IL128497A0 (en) 2000-01-31
KR20010029474A (ko) 2001-04-06

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