HUE062092T2 - Neuropátiás fájdalom kezelésére szolgáló, alacsony koncentrációjú FLT-receptorgátló - Google Patents
Neuropátiás fájdalom kezelésére szolgáló, alacsony koncentrációjú FLT-receptorgátlóInfo
- Publication number
- HUE062092T2 HUE062092T2 HUE17727913A HUE17727913A HUE062092T2 HU E062092 T2 HUE062092 T2 HU E062092T2 HU E17727913 A HUE17727913 A HU E17727913A HU E17727913 A HUE17727913 A HU E17727913A HU E062092 T2 HUE062092 T2 HU E062092T2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- neuropathic pain
- low dosage
- receptor inhibitor
- flt3 receptor
- Prior art date
Links
- 101100335081 Mus musculus Flt3 gene Proteins 0.000 title 1
- 208000004296 neuralgia Diseases 0.000 title 1
- 208000021722 neuropathic pain Diseases 0.000 title 1
- 108091006082 receptor inhibitors Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Anesthesiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16305669.0A EP3254698A1 (en) | 2016-06-08 | 2016-06-08 | Flt3 receptor inhibitor at low dosage for the treatment of neuropathic pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE062092T2 true HUE062092T2 (hu) | 2023-09-28 |
Family
ID=56134285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17727913A HUE062092T2 (hu) | 2016-06-08 | 2017-06-08 | Neuropátiás fájdalom kezelésére szolgáló, alacsony koncentrációjú FLT-receptorgátló |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10709687B2 (enExample) |
| EP (2) | EP3254698A1 (enExample) |
| JP (1) | JP7134097B2 (enExample) |
| HU (1) | HUE062092T2 (enExample) |
| WO (1) | WO2017211937A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020212395A1 (en) * | 2019-04-16 | 2020-10-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of jak inhibitors for the treatment of painful conditions involving nav1.7 channels |
| US12441707B2 (en) | 2019-12-30 | 2025-10-14 | Tyra Biosciences, Inc. | Indazole compounds |
| KR102231446B1 (ko) * | 2021-01-21 | 2021-03-24 | (주) 와이디생명과학 | 베타아밀로이드 및 타우 단백질 집적과 연관된 질환 치료용 약학적 조성물 |
| PE20242008A1 (es) | 2021-12-30 | 2024-10-03 | Biomea Fusion Inc | Compuestos de pirazina como inhibidores de flt3 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002032861A2 (en) | 2000-10-17 | 2002-04-25 | Merck & Co., Inc. | Orally active salts with tyrosine kinase activity |
| AR035885A1 (es) | 2001-05-14 | 2004-07-21 | Novartis Ag | Derivados de 4-amino-5-fenil-7-ciclobutilpirrolo (2,3-d)pirimidina, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos derivados para la preparacion de una composicion farmaceutica |
| WO2003024969A1 (en) | 2001-09-14 | 2003-03-27 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| WO2003024931A1 (en) | 2001-09-14 | 2003-03-27 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| TWI259081B (en) | 2001-10-26 | 2006-08-01 | Sugen Inc | Treatment of acute myeloid leukemia with indolinone compounds |
| TWI302836B (en) | 2001-10-30 | 2008-11-11 | Novartis Ag | Staurosporine derivatives as inhibitors of flt3 receptor tyrosine kinase activity |
| MXPA04006271A (es) | 2001-12-27 | 2004-10-04 | Theravance Inc | Derivados de indolinona utiles como inhibidores de la proteina cinasa. |
| PE20040522A1 (es) | 2002-05-29 | 2004-09-28 | Novartis Ag | Derivados de diarilurea dependientes de la cinasa de proteina |
| GB0215676D0 (en) | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| MXPA05001804A (es) | 2002-08-14 | 2005-05-27 | Vertex Pharma | Inhibidores de proteinas cinasas y usos de los mismos. |
| CA2496164C (en) | 2002-08-23 | 2010-11-09 | Chiron Corporation | Benzimidazole quinolinones and uses thereof |
| US20080207617A1 (en) | 2002-10-29 | 2008-08-28 | Kirin Beer Kabushiki Kaisha | Quinoline Derivatives and Quinazoline Derivatives Inhibiting Autophosphrylation of Flt3 and Medicinal Compositions Containing the Same |
| US7838527B2 (en) | 2002-11-13 | 2010-11-23 | Novartis Vaccines And Diagnostics, Inc. | Methods of treating cancer and related methods |
| AR042052A1 (es) | 2002-11-15 | 2005-06-08 | Vertex Pharma | Diaminotriazoles utiles como inhibidores de proteinquinasas |
| AU2003297160A1 (en) | 2002-12-18 | 2004-07-22 | Vertex Pharmaceuticals Incorporated | Benzisoxazole derivatives useful as inhibitors of protein kinases |
| US20060281788A1 (en) | 2005-06-10 | 2006-12-14 | Baumann Christian A | Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor |
| EP1951234A2 (en) | 2005-10-18 | 2008-08-06 | Janssen Pharmaceutica N.V. | Method of inhibiting flt3 kinase |
| EP2001892B1 (en) | 2006-03-17 | 2013-04-24 | Ambit Biosciences Corporation | Imidazolothiazole compounds for the treatment of proliferative diseases |
| JP5645667B2 (ja) | 2007-11-08 | 2014-12-24 | アムビト ビオスシエンセス コルポラチオン | 増殖性疾患を治療するための、Ｎ−（５−ｔｅｒｔ−ブチル−イソキサゾール−３−イル）−Ｎ’−｛４−［７−（２−モルホリン−４−イル−エトキシ）イミダゾ［２，ｌ−ｂ］［ｌ，３］ベンゾチアゾール−２−イル］フェニル｝尿素の投与方法 |
| US8436171B2 (en) | 2008-02-01 | 2013-05-07 | Akinion Pharmaceuticals Ab | Amino substituted pyrazines as inhibitors or protein kinases |
| EP2521782B1 (en) | 2010-01-05 | 2019-04-10 | INSERM - Institut National de la Santé et de la Recherche Médicale | Flt3 receptor antagonists for the treatment or the prevention of pain disorders |
| WO2016016370A1 (en) * | 2014-07-31 | 2016-02-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Flt3 receptor antagonists |
-
2016
- 2016-06-08 EP EP16305669.0A patent/EP3254698A1/en not_active Withdrawn
-
2017
- 2017-06-08 JP JP2018563716A patent/JP7134097B2/ja active Active
- 2017-06-08 EP EP17727913.0A patent/EP3468602B1/en active Active
- 2017-06-08 HU HUE17727913A patent/HUE062092T2/hu unknown
- 2017-06-08 WO PCT/EP2017/063935 patent/WO2017211937A1/en not_active Ceased
- 2017-06-08 US US16/307,968 patent/US10709687B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3468602B1 (en) | 2023-02-22 |
| WO2017211937A1 (en) | 2017-12-14 |
| EP3468602A1 (en) | 2019-04-17 |
| JP7134097B2 (ja) | 2022-09-09 |
| JP2019517536A (ja) | 2019-06-24 |
| EP3254698A1 (en) | 2017-12-13 |
| US20190298691A1 (en) | 2019-10-03 |
| US10709687B2 (en) | 2020-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3180009A4 (en) | Zoledronic acid dosage forms for the treatment of pain | |
| IL253945A0 (en) | kdm1a inhibitors to treat the disease | |
| IL262159A (en) | Equipment for implanting medical devices | |
| IL270752B (en) | Pyrrolopyridine-aniline compounds for the treatment of skin disorders | |
| IL276482A (en) | Compounds for pain management | |
| PL3424499T3 (pl) | Kompozycja farmaceutyczna do leczenia bólu neuropatycznego | |
| ZA201705847B (en) | Treatment of pain | |
| PT3180434T (pt) | Chamarizes oligonucleotídicos para o tratamento da dor | |
| GB201506654D0 (en) | Formulations for inhibition of PCSK9 for the treatment of hypercholesterolemia | |
| HUE062092T2 (hu) | Neuropátiás fájdalom kezelésére szolgáló, alacsony koncentrációjú FLT-receptorgátló | |
| GB201604658D0 (en) | Treatment for pain | |
| IL266243A (en) | Use of senicapoc for the treatment of neuropathic pain | |
| ZA201804588B (en) | Pharmaceutical formulations for the treatment of diabetes | |
| IL258316A (en) | A combination of trazodone and gabapentin for the treatment of pain | |
| PL3178521T3 (pl) | Urządzenie do leczenia zintegrowanego rytmu serca | |
| IL273364A (en) | MPGES-1 inhibitor for the treatment of osteoarthritis pain | |
| PL3638223T3 (pl) | Bromheksyna w leczeniu bólu | |
| GB201714772D0 (en) | Dosage forms of therapeutic compounds | |
| GB201714241D0 (en) | Pharmaceutical compositions for the treatment of proteinopathies | |
| HK40002410A (en) | Inhibitors of beta-arrestin-neurokinin 1 receptor interactions for the treatment of pain | |
| AU2016900635A0 (en) | Inhibitors of beta-arrestin-Neurokinin 1 Receptor Interactions for the Treatment of Pain | |
| GB201701928D0 (en) | Compounds for the treatment of hyperglycaemia | |
| PT3185855T (pt) | Comprimido revestido por película para o tratamento da dor aguda | |
| GB201603752D0 (en) | Treatment of hypothyroidism | |
| GB201603755D0 (en) | Treatment of hypothyroidism |