HUE055634T2 - Dopamin D3 receptor szelektív antagonisták/részleges antagonisták; eljárás azok elõállítására; és alkalmazásuk - Google Patents
Dopamin D3 receptor szelektív antagonisták/részleges antagonisták; eljárás azok elõállítására; és alkalmazásukInfo
- Publication number
- HUE055634T2 HUE055634T2 HUE17711971A HUE17711971A HUE055634T2 HU E055634 T2 HUE055634 T2 HU E055634T2 HU E17711971 A HUE17711971 A HU E17711971A HU E17711971 A HUE17711971 A HU E17711971A HU E055634 T2 HUE055634 T2 HU E055634T2
- Authority
- HU
- Hungary
- Prior art keywords
- dopamine
- making
- partial agonists
- selective antagonists
- receptor selective
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662307600P | 2016-03-14 | 2016-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE055634T2 true HUE055634T2 (hu) | 2021-12-28 |
Family
ID=58358971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE17711971A HUE055634T2 (hu) | 2016-03-14 | 2017-03-08 | Dopamin D3 receptor szelektív antagonisták/részleges antagonisták; eljárás azok elõállítására; és alkalmazásuk |
Country Status (13)
Country | Link |
---|---|
US (1) | US20220185798A1 (hu) |
EP (2) | EP3429993B1 (hu) |
AU (1) | AU2017233716B2 (hu) |
CA (1) | CA3017342A1 (hu) |
DK (1) | DK3429993T3 (hu) |
ES (1) | ES2881267T3 (hu) |
HR (1) | HRP20211182T1 (hu) |
HU (1) | HUE055634T2 (hu) |
PL (1) | PL3429993T3 (hu) |
PT (1) | PT3429993T (hu) |
RS (1) | RS62156B1 (hu) |
SI (1) | SI3429993T1 (hu) |
WO (1) | WO2017160552A1 (hu) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11337971B2 (en) | 2018-09-11 | 2022-05-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dopamine D3 receptor selective antagonists/partial agonists and uses thereof |
WO2023014768A1 (en) * | 2021-08-03 | 2023-02-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | D3 dopamine receptor-selective negative allosteric modulators |
CN114409621B (zh) * | 2022-02-09 | 2023-09-08 | 江苏省原子医学研究所 | 一种靶向多巴胺d3受体的诊疗药物及其应用 |
WO2023192145A1 (en) * | 2022-03-30 | 2023-10-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Synthesis of dopamine d3 receptor selective antagonists/partial agonists |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0103987A3 (en) * | 2001-09-28 | 2004-11-29 | Richter Gedeon Vegyeszet | Phenylpiperazinylalkyl carboxylic acid amid derivatives, process for their preparation, pharmaceutical compositions containing them and their intermediates |
ES2734268T3 (es) * | 2012-10-11 | 2019-12-05 | Southern Res Inst | Derivados de urea y amida de aminoalquilpiperazinas y uso de los mismos |
-
2017
- 2017-03-08 ES ES17711971T patent/ES2881267T3/es active Active
- 2017-03-08 EP EP17711971.6A patent/EP3429993B1/en active Active
- 2017-03-08 PL PL17711971T patent/PL3429993T3/pl unknown
- 2017-03-08 CA CA3017342A patent/CA3017342A1/en active Pending
- 2017-03-08 WO PCT/US2017/021328 patent/WO2017160552A1/en active Application Filing
- 2017-03-08 DK DK17711971.6T patent/DK3429993T3/da active
- 2017-03-08 EP EP21158632.6A patent/EP3848351A1/en active Pending
- 2017-03-08 RS RS20210938A patent/RS62156B1/sr unknown
- 2017-03-08 SI SI201730863T patent/SI3429993T1/sl unknown
- 2017-03-08 AU AU2017233716A patent/AU2017233716B2/en active Active
- 2017-03-08 PT PT177119716T patent/PT3429993T/pt unknown
- 2017-03-08 HU HUE17711971A patent/HUE055634T2/hu unknown
-
2021
- 2021-07-22 HR HRP20211182TT patent/HRP20211182T1/hr unknown
-
2022
- 2022-03-03 US US17/685,709 patent/US20220185798A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
PT3429993T (pt) | 2021-07-19 |
PL3429993T3 (pl) | 2021-11-15 |
ES2881267T3 (es) | 2021-11-29 |
CA3017342A1 (en) | 2017-09-21 |
DK3429993T3 (da) | 2021-08-09 |
EP3429993B1 (en) | 2021-05-26 |
HRP20211182T1 (hr) | 2021-10-15 |
AU2017233716A1 (en) | 2018-10-04 |
WO2017160552A1 (en) | 2017-09-21 |
SI3429993T1 (sl) | 2021-09-30 |
AU2017233716B2 (en) | 2020-10-29 |
RS62156B1 (sr) | 2021-08-31 |
EP3848351A1 (en) | 2021-07-14 |
US20220185798A1 (en) | 2022-06-16 |
EP3429993A1 (en) | 2019-01-23 |
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