HUE052204T2 - Eljárás nitrogén-monoxidot leadó prosztaglandin analógok elõállítására - Google Patents
Eljárás nitrogén-monoxidot leadó prosztaglandin analógok elõállításáraInfo
- Publication number
- HUE052204T2 HUE052204T2 HUE18157888A HUE18157888A HUE052204T2 HU E052204 T2 HUE052204 T2 HU E052204T2 HU E18157888 A HUE18157888 A HU E18157888A HU E18157888 A HUE18157888 A HU E18157888A HU E052204 T2 HUE052204 T2 HU E052204T2
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- nitric oxide
- prostaglandin analogue
- oxide donating
- donating prostaglandin
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title 2
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/02—Preparation of esters of nitric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C203/00—Esters of nitric or nitrous acid
- C07C203/02—Esters of nitric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18157888.1A EP3530649B1 (en) | 2018-02-21 | 2018-02-21 | Process for the preparation of a nitric oxide donating prostaglandin analogue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE052204T2 true HUE052204T2 (hu) | 2021-04-28 |
Family
ID=61563114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18157888A HUE052204T2 (hu) | 2018-02-21 | 2018-02-21 | Eljárás nitrogén-monoxidot leadó prosztaglandin analógok elõállítására |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10988438B2 (hu) |
| EP (2) | EP3757089B1 (hu) |
| JP (2) | JP7365349B2 (hu) |
| KR (1) | KR20200123151A (hu) |
| CN (1) | CN111757868B (hu) |
| AR (1) | AR114262A1 (hu) |
| CA (1) | CA3089530A1 (hu) |
| ES (2) | ES2923623T3 (hu) |
| HU (1) | HUE052204T2 (hu) |
| PH (1) | PH12020551320A1 (hu) |
| PT (1) | PT3530649T (hu) |
| SG (1) | SG11202007113XA (hu) |
| TW (1) | TWI805692B (hu) |
| WO (1) | WO2019162149A1 (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE064405T2 (hu) * | 2019-08-05 | 2024-03-28 | Nicox Sa | Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására |
| WO2022167070A1 (en) | 2021-02-03 | 2022-08-11 | Nicox S.A. | Process for the preparation of a nitric oxide donating prostaglandin analogue |
| JP2024533601A (ja) | 2021-09-20 | 2024-09-12 | ニコックス エス．エー． | 神経保護剤としての一酸化窒素放出プロスタミド |
| DK4303211T3 (da) | 2022-07-07 | 2024-10-07 | Nicox S A | Industriel fremgangsmåde til fremstilling af hexansyre, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl-ester og produkt med høj renhed |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR076731A1 (es) * | 2008-05-09 | 2011-07-06 | Pfizer | Prostamidas donadoras de oxido nitrico, uso de los mismos y composiciones farmaceuticas |
| CN103288698A (zh) * | 2013-05-07 | 2013-09-11 | 北京洛斯顿精细化工有限公司 | 一种合成前列素类似物的新方法 |
| JP6279409B2 (ja) * | 2014-06-02 | 2018-02-14 | 株式会社ダイセル | ポスト処理を行ったスズ置換ゼオライト・ベータを用いたケトン類のエステル類への酸化 |
| US10280138B2 (en) | 2015-03-31 | 2019-05-07 | Nicox S.A. | Nitric oxide donating derivatives of fluprostenol |
-
2018
- 2018-02-21 EP EP20185329.8A patent/EP3757089B1/en active Active
- 2018-02-21 PT PT181578881T patent/PT3530649T/pt unknown
- 2018-02-21 HU HUE18157888A patent/HUE052204T2/hu unknown
- 2018-02-21 ES ES20185329T patent/ES2923623T3/es active Active
- 2018-02-21 ES ES18157888T patent/ES2836118T3/es active Active
- 2018-02-21 EP EP18157888.1A patent/EP3530649B1/en active Active
-
2019
- 2019-02-12 CA CA3089530A patent/CA3089530A1/en active Pending
- 2019-02-12 KR KR1020207025676A patent/KR20200123151A/ko not_active Application Discontinuation
- 2019-02-12 SG SG11202007113XA patent/SG11202007113XA/en unknown
- 2019-02-12 WO PCT/EP2019/053455 patent/WO2019162149A1/en active Application Filing
- 2019-02-12 JP JP2020544224A patent/JP7365349B2/ja active Active
- 2019-02-12 CN CN201980013990.3A patent/CN111757868B/zh active Active
- 2019-02-12 US US16/967,057 patent/US10988438B2/en active Active
- 2019-02-18 TW TW108105320A patent/TWI805692B/zh active
- 2019-02-22 AR ARP190100442A patent/AR114262A1/es unknown
-
2020
- 2020-08-11 PH PH12020551320A patent/PH12020551320A1/en unknown
-
2023
- 2023-10-06 JP JP2023174240A patent/JP2024009896A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT3530649T (pt) | 2020-12-04 |
| TW202000643A (zh) | 2020-01-01 |
| JP2024009896A (ja) | 2024-01-23 |
| ES2923623T3 (es) | 2022-09-29 |
| WO2019162149A1 (en) | 2019-08-29 |
| EP3757089B1 (en) | 2022-05-11 |
| SG11202007113XA (en) | 2020-09-29 |
| TWI805692B (zh) | 2023-06-21 |
| CA3089530A1 (en) | 2019-08-29 |
| US20210040032A1 (en) | 2021-02-11 |
| AR114262A1 (es) | 2020-08-12 |
| EP3530649A1 (en) | 2019-08-28 |
| JP7365349B2 (ja) | 2023-10-19 |
| CN111757868B (zh) | 2023-03-14 |
| ES2836118T3 (es) | 2021-06-24 |
| US10988438B2 (en) | 2021-04-27 |
| EP3530649B1 (en) | 2020-09-30 |
| JP2021514371A (ja) | 2021-06-10 |
| PH12020551320A1 (en) | 2021-04-26 |
| EP3757089A1 (en) | 2020-12-30 |
| KR20200123151A (ko) | 2020-10-28 |
| CN111757868A (zh) | 2020-10-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL276917A (en) | A process for the preparation of alubixivet | |
| SG11202007113XA (en) | Process for the preparation of a nitric oxide donating prostaglandin analogue | |
| GB2593352B (en) | Process for the preparation of 3alpha-hydroxy-5alpha-pregnan-20-one (brexanolone) | |
| EP3444097C0 (de) | Verfahren zur herstellung eines rohrs | |
| PL3765440T3 (pl) | Sposób wytwarzania n-alkilonitratoetylonitroamin | |
| HUE064405T2 (hu) | Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására | |
| IL289904A (en) | A process for preparing biphenylamines | |
| IL281254A (en) | A process for the preparation of lanbatinib | |
| IL275381A (en) | A process for the preparation of Crisborole | |
| EP3877361C0 (en) | PROCESS FOR PREPARING ARYLSULFONYLPROPENENITRILE | |
| EP3847675C0 (en) | PROCESS FOR THE PRODUCTION OF GALLIUM RADIONUCLIDES | |
| EP3884942A4 (en) | USE OF BULLEYACONITINE A | |
| IL289971A (en) | Improved methods for the production of plants | |
| IL286054A (en) | A process for the preparation of a modified imidazoquinoline | |
| IL283633A (en) | A process for preparing a cyclic dinucleotide | |
| EP3359716A4 (en) | PROCESS FOR MANUFACTURING A SHAPED BODY | |
| IL277956B1 (en) | Process for preparing Ilufrost | |
| GB201915206D0 (en) | Use of cyclodextrins as a radiostabilizer | |
| PL3599256T3 (pl) | Sposób wytwarzania poliorganosiloksanów | |
| ZA202102159B (en) | Process for the preparation of a flavouring | |
| IL276557A (en) | A process for making metformin | |
| HUP1800278A2 (en) | Process for the preparation of boc-linagliptin | |
| GB2573115B (en) | Process for the preparation of oxamyl | |
| PT3609337T (pt) | Método para o fabrico de uma composição intensificadora de aroma | |
| GB201804772D0 (en) | A preparation method of high purity ginkgolide |