HUE049818T2 - Szelektíven deglikozilált D-vitamint kötõ protein (GcMAF), kolekalciferol (kalciol) és gyártási eljárás - Google Patents

Szelektíven deglikozilált D-vitamint kötõ protein (GcMAF), kolekalciferol (kalciol) és gyártási eljárás

Info

Publication number
HUE049818T2
HUE049818T2 HUE17723236A HUE17723236A HUE049818T2 HU E049818 T2 HUE049818 T2 HU E049818T2 HU E17723236 A HUE17723236 A HU E17723236A HU E17723236 A HUE17723236 A HU E17723236A HU E049818 T2 HUE049818 T2 HU E049818T2
Authority
HU
Hungary
Prior art keywords
calciol
gcmaf
cholecalciferol
production method
binding protein
Prior art date
Application number
HUE17723236A
Other languages
English (en)
Inventor
Ralf Herwig
Joachim Greilberger
Original Assignee
Hg Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hg Pharma Gmbh filed Critical Hg Pharma Gmbh
Publication of HUE049818T2 publication Critical patent/HUE049818T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1722—Plasma globulins, lactoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE17723236A 2016-04-21 2017-04-21 Szelektíven deglikozilált D-vitamint kötõ protein (GcMAF), kolekalciferol (kalciol) és gyártási eljárás HUE049818T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ATA50354/2016A AT518622A1 (de) 2016-04-21 2016-04-21 Dimerer Komplex aus selektiv deglycosyliertem Vitamin D bindenden Protein (GcMAF) und Cholecalciferol (Calciol) und Verfahren zu dessen Herstellung

Publications (1)

Publication Number Publication Date
HUE049818T2 true HUE049818T2 (hu) 2020-10-28

Family

ID=58707253

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17723236A HUE049818T2 (hu) 2016-04-21 2017-04-21 Szelektíven deglikozilált D-vitamint kötõ protein (GcMAF), kolekalciferol (kalciol) és gyártási eljárás

Country Status (13)

Country Link
US (1) US20190134064A1 (hu)
EP (1) EP3445777B1 (hu)
JP (1) JP6862536B2 (hu)
CN (1) CN109415428B (hu)
AT (1) AT518622A1 (hu)
AU (1) AU2017254728B2 (hu)
CA (1) CA3021701A1 (hu)
CY (1) CY1123003T1 (hu)
ES (1) ES2794791T3 (hu)
HU (1) HUE049818T2 (hu)
PL (1) PL3445777T3 (hu)
PT (1) PT3445777T (hu)
WO (1) WO2017181213A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT521556A1 (de) * 2018-07-24 2020-02-15 Hg Pharma Gmbh Vitamin D bindendes Protein

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177001A (en) * 1989-11-20 1993-01-05 Nobuto Yamamoto In vitro enzymatic conversion of glycosylated mammalian vitamin D-binding protein to a potent macrophage activating factor
US6410269B1 (en) * 1995-06-07 2002-06-25 Nobuto Yamamoto Preparation of potent macrophage activating factors derived from cloned vitamin D binding protein and its domain and their therapeutic usage for cancer, HIV-infection and osteopetrosis
AU2001261378B2 (en) * 2000-05-09 2005-03-17 Children's Medical Center Corporation Method and composition for the treatment of angiogenesis
US7754693B2 (en) * 2006-02-16 2010-07-13 Young Hee Ko Composition and method for the efficacious and safe administration of halopyruvate for the treatment of cancer
CA2832487A1 (en) * 2011-04-07 2012-10-11 Efranat Ltd. Macrophage activating factor for pharmaceutical compositions
WO2014202956A1 (en) * 2013-06-21 2014-12-24 Noakes, David Vitamin d complexes with de-vdbp and an unsaturated fatty acid, and their use in therapy

Also Published As

Publication number Publication date
ES2794791T3 (es) 2020-11-19
PL3445777T3 (pl) 2020-08-10
PT3445777T (pt) 2020-05-29
CY1123003T1 (el) 2021-10-29
US20190134064A1 (en) 2019-05-09
JP6862536B2 (ja) 2021-04-21
CN109415428A (zh) 2019-03-01
CA3021701A1 (en) 2017-10-26
CN109415428B (zh) 2022-03-29
EP3445777B1 (de) 2020-02-26
AU2017254728B2 (en) 2021-08-26
WO2017181213A1 (de) 2017-10-26
AT518622A1 (de) 2017-11-15
JP2019515953A (ja) 2019-06-13
AU2017254728A1 (en) 2018-12-06
EP3445777A1 (de) 2019-02-27

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