HUE049786T2 - Arilalkilamin vegyületek rák megelõzésében vagy kezelésében történõ alkalmazásra - Google Patents

Arilalkilamin vegyületek rák megelõzésében vagy kezelésében történõ alkalmazásra

Info

Publication number
HUE049786T2
HUE049786T2 HUE15825824A HUE15825824A HUE049786T2 HU E049786 T2 HUE049786 T2 HU E049786T2 HU E15825824 A HUE15825824 A HU E15825824A HU E15825824 A HUE15825824 A HU E15825824A HU E049786 T2 HUE049786 T2 HU E049786T2
Authority
HU
Hungary
Prior art keywords
cancer
prevention
treatment
arylalkylamine compounds
arylalkylamine
Prior art date
Application number
HUE15825824A
Other languages
English (en)
Inventor
Jozsef Knoll
Ildiko Miklya
Peter Ferdinandy
Dezsoe Schuler
Zsuzsanna Schaff
Sandor Eckhardt
Original Assignee
Semmelweis Univ
Fujimoto Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Semmelweis Univ, Fujimoto Co Ltd filed Critical Semmelweis Univ
Publication of HUE049786T2 publication Critical patent/HUE049786T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HUE15825824A 2014-12-05 2015-12-07 Arilalkilamin vegyületek rák megelõzésében vagy kezelésében történõ alkalmazásra HUE049786T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14196623 2014-12-05

Publications (1)

Publication Number Publication Date
HUE049786T2 true HUE049786T2 (hu) 2020-10-28

Family

ID=52015934

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE15825824A HUE049786T2 (hu) 2014-12-05 2015-12-07 Arilalkilamin vegyületek rák megelõzésében vagy kezelésében történõ alkalmazásra
HUE15825825A HUE050756T2 (hu) 2014-12-05 2015-12-07 Arilalkilamin vegyületek rák megelõzésében vagy kezelésében történõ alkalmazásra

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE15825825A HUE050756T2 (hu) 2014-12-05 2015-12-07 Arilalkilamin vegyületek rák megelõzésében vagy kezelésében történõ alkalmazásra

Country Status (9)

Country Link
US (2) US10258599B2 (hu)
EP (2) EP3226852B1 (hu)
JP (2) JP6875278B2 (hu)
CN (2) CN107205966B (hu)
CA (2) CA2968793C (hu)
HU (2) HUE049786T2 (hu)
IL (2) IL252493B (hu)
RU (2) RU2714893C2 (hu)
WO (2) WO2016088112A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2968793C (en) 2014-12-05 2022-02-08 Semmelweis University Compounds for use in the prevention or treatment of cancer
KR102440763B1 (ko) 2019-05-20 2022-09-05 맙플렉스 인터내셔널 컴퍼니 리미티드 항체-약물 접합체의 중간체를 제조하는 원-포트 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (hu) 1969-02-06 1970-12-24 Bellon Labor Sa Roger
FR2536749A1 (fr) 1982-11-25 1984-06-01 Cerm Cent Europ Rech Mauvernay (amino-2 ethyl)-6 benzoxazolinones substituees, leur preparation et leurs applications en therapeutique
EP0252005B1 (de) 1986-06-26 1991-07-10 Ciba-Geigy Ag Hydrierte 1-Benzooxacycloalkyl-pyridincarbonsäureverbindungen
HU207280B (en) 1986-09-25 1993-03-29 Chinoin Gyogyszer Es Vegyeszet Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them
US5783606A (en) * 1995-02-10 1998-07-21 The University Of Toronto Innovations Foundation Deprenyl compounds for treatment of glaucoma
JP2917189B2 (ja) 1992-09-21 1999-07-12 株式会社間組 ブロック製造用型枠及びブロックの製造法
JPH09247445A (ja) 1996-03-05 1997-09-19 Ricoh Co Ltd 画像読取装置
WO1999007667A1 (fr) * 1997-08-07 1999-02-18 Fujimoto Brothers Co., Ltd. Nouveaux derives d'ethylamine
CA2318693A1 (en) * 1998-01-13 1999-07-22 University Of Saskatchewan Technologies Inc. Composition containing propargylamine for enhancing cancer therapy
JP4499208B2 (ja) 1998-10-29 2010-07-07 株式会社フジモト・コーポレーション 新規な光学活性アミノペンタン誘導体
JP4953041B2 (ja) 2001-09-19 2012-06-13 株式会社フジモト・コーポレーション アポトーシス抑制剤
JP4953040B2 (ja) 2001-09-19 2012-06-13 株式会社フジモト・コーポレーション アポトーシス抑制剤
US20040266808A1 (en) * 2003-06-27 2004-12-30 Kamen Barton A. Treatment of antifolate neurotoxicity
JP5030194B2 (ja) 2004-11-25 2012-09-19 国立大学法人九州大学 薬物依存症治療剤
GB2451495A (en) * 2007-08-01 2009-02-04 Inion Ltd Treatment of inflammation by modulating catecholamine metabolism
RU2453309C1 (ru) * 2011-05-11 2012-06-20 Государственное образовательное учреждение высшего профессионального образования Пущинский государственный университет Средство, обладающее цитотоксической активностью по отношению к раковым клеткам человека в культуре
EP2736506B1 (en) * 2011-07-26 2018-09-05 University Of Southern California Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer
CA2853729A1 (en) 2011-10-28 2013-05-02 Board Of Regents, The University Of Texas System Novel compositions and methods for treating cancer
CA2968793C (en) 2014-12-05 2022-02-08 Semmelweis University Compounds for use in the prevention or treatment of cancer

Also Published As

Publication number Publication date
IL252493A0 (en) 2017-07-31
CA2968806A1 (en) 2016-06-09
CN107205966A (zh) 2017-09-26
US20170340582A1 (en) 2017-11-30
WO2016088112A1 (en) 2016-06-09
RU2017122192A (ru) 2019-01-09
EP3226852B1 (en) 2020-03-18
US10258598B2 (en) 2019-04-16
CN107205965A (zh) 2017-09-26
JP6875278B2 (ja) 2021-05-19
IL252487A0 (en) 2017-07-31
HUE050756T2 (hu) 2021-01-28
EP3226852A1 (en) 2017-10-11
IL252493B (en) 2020-04-30
JP6875279B2 (ja) 2021-05-19
EP3226851A1 (en) 2017-10-11
US10258599B2 (en) 2019-04-16
CN107205966B (zh) 2021-01-26
RU2731102C2 (ru) 2020-08-28
US20170319535A1 (en) 2017-11-09
RU2714893C2 (ru) 2020-02-20
JP2018505852A (ja) 2018-03-01
RU2017122192A3 (hu) 2019-06-20
RU2017122205A (ru) 2019-01-11
JP2018505851A (ja) 2018-03-01
CN107205965B (zh) 2020-10-27
CA2968793C (en) 2022-02-08
WO2016088111A1 (en) 2016-06-09
EP3226851B1 (en) 2020-03-18
IL252487B (en) 2019-12-31
CA2968793A1 (en) 2016-06-09
RU2017122205A3 (hu) 2019-07-17

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