HUE048702T2 - Fibroinból származó fehérjekészítmény - Google Patents
Fibroinból származó fehérjekészítményInfo
- Publication number
- HUE048702T2 HUE048702T2 HUE15833824A HUE15833824A HUE048702T2 HU E048702 T2 HUE048702 T2 HU E048702T2 HU E15833824 A HUE15833824 A HU E15833824A HU E15833824 A HUE15833824 A HU E15833824A HU E048702 T2 HUE048702 T2 HU E048702T2
- Authority
- HU
- Hungary
- Prior art keywords
- fibroin
- protein composition
- derived protein
- derived
- composition
- Prior art date
Links
- 108010022355 Fibroins Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43586—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from silkworms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/66—Proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Insects & Arthropods (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Animal Husbandry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462039675P | 2014-08-20 | 2014-08-20 | |
| US201562193790P | 2015-07-17 | 2015-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE048702T2 true HUE048702T2 (hu) | 2020-07-28 |
Family
ID=55351259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE15833824A HUE048702T2 (hu) | 2014-08-20 | 2015-08-20 | Fibroinból származó fehérjekészítmény |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US9394355B2 (hu) |
| EP (1) | EP3182985B1 (hu) |
| JP (1) | JP6632161B2 (hu) |
| KR (1) | KR102539012B1 (hu) |
| CN (1) | CN107105724B (hu) |
| AU (1) | AU2015305386B2 (hu) |
| CA (1) | CA2994222C (hu) |
| DK (1) | DK3182985T3 (hu) |
| ES (1) | ES2781114T3 (hu) |
| HU (1) | HUE048702T2 (hu) |
| SG (1) | SG11201704010UA (hu) |
| WO (1) | WO2016029034A1 (hu) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2781114T3 (es) * | 2014-08-20 | 2020-08-28 | Silk Tech Ltd | Composición proteica derivada de fibroína |
| CA3020342A1 (en) * | 2016-04-08 | 2017-11-23 | Cornell University | A method to enhance wound healing using silk-derived protein |
| US11242367B2 (en) | 2016-08-12 | 2022-02-08 | Silk Technologies, Ltd. | Silk-derived protein for treating inflammation |
| CN107326057A (zh) * | 2017-07-28 | 2017-11-07 | 浙江理工大学 | 一种利用离子液体和蛋白酶提取桑蚕丝丝素蛋白的方法 |
| CN112533626A (zh) | 2018-06-04 | 2021-03-19 | 柯坤生物科技公司 | 丝基产品制剂和使用方法 |
| JPWO2020054873A1 (ja) * | 2018-09-14 | 2021-08-30 | Ｓｐｉｂｅｒ株式会社 | フィブロイン溶液を製造する方法、及びタンパク質成形体を製造する方法 |
| JP2022529644A (ja) * | 2019-04-16 | 2022-06-23 | エボルブド バイ ネイチャー， インコーポレイテッド | 絹毛髪ケア組成物 |
| CN109833294B (zh) * | 2019-04-19 | 2020-06-09 | 江苏远恒药业有限公司 | 一种盐酸洛美沙星滴眼液及其制备工艺 |
| AU2020288624A1 (en) | 2019-06-04 | 2022-02-03 | Cocoon Biotech Inc. | Silk-based products, formulations, and methods of use |
| JP2023502591A (ja) * | 2019-11-15 | 2023-01-25 | シルク テクノロジーズ、リミテッド | 絹由来タンパク質の安定した配合物 |
| KR102295015B1 (ko) * | 2020-03-27 | 2021-08-27 | 주식회사 바이오스탠다드 | 수용화 상태로 장기간 안정성을 가지는 실크 피브로인 단백질 수용액 |
| KR102365211B1 (ko) * | 2020-03-27 | 2022-02-18 | (주)네이처앤트리 | 생리활성 실크 피브로인 단백질의 양전하 치환 조성을 포함하는 극손상 모발 보호용 코팅제재 |
| KR102194995B1 (ko) * | 2020-09-16 | 2020-12-28 | 장혜란 | 진단을 위한 개선된 건조체액의 안정화 조성물 및 이의 응용방법 |
| US20220331400A1 (en) * | 2021-04-14 | 2022-10-20 | Cocoon Biotech Inc. | Methods of making stable silk fibroin formulations |
| KR102385695B1 (ko) * | 2021-04-15 | 2022-04-12 | 남기준 | 세미-아이피엔 구조를 이루는 연조직 수복 및 확대를 위한 신규한 히알루론-복합 아미노 하이드로 겔 조성물 및 이의 용도 |
| WO2024059862A2 (en) * | 2022-09-15 | 2024-03-21 | Evolved By Nature, Inc. | Fibroin peptides and protein fragments compositions |
Family Cites Families (52)
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| JPS5931520B2 (ja) | 1979-03-22 | 1984-08-02 | カネボウ株式会社 | 絹フイブロインペプチド水溶液の製造法 |
| JPH02277885A (ja) * | 1989-04-17 | 1990-11-14 | Shigesaburo Mizushima | ヒブロイン蛋白による絹繊維加工方法 |
| CA2125060C (en) | 1993-07-02 | 1999-03-30 | Henry P. Dabrowski | Ophthalmic solution for artificial tears |
| JPH0767686A (ja) | 1993-09-06 | 1995-03-14 | Shinano Kenshi Co Ltd | 低分子量の絹フィブロインペプチドの製造方法 |
| US5760004A (en) | 1994-11-21 | 1998-06-02 | Protein Polymer Technologies, Inc. | Chemical modification of repetitive polymers to enhance water solubility |
| US5895645A (en) | 1995-01-31 | 1999-04-20 | Bausch & Lomb Incorporated | Opthalmic solution for artificial tears |
| JPH08295697A (ja) | 1995-04-26 | 1996-11-12 | Kanebo Ltd | 高濃度絹フィブロイン水溶液の製造方法 |
| WO1999033899A1 (en) | 1997-12-31 | 1999-07-08 | Kimberly-Clark Worlwide, Inc. | Method of reducing molecular weights and polydispersity indices of polymers of ethylene oxide |
| FR2774588B1 (fr) | 1998-02-11 | 2000-05-05 | Oreal | Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue |
| JP2000143472A (ja) | 1998-11-10 | 2000-05-23 | Hiroshi Akai | 紫外線吸収機能を有する化粧剤 |
| US20030206897A1 (en) | 2000-09-13 | 2003-11-06 | The Procter & Gamble Company | Cosmetic compositions |
| IT1316885B1 (it) * | 2000-10-02 | 2003-05-13 | Consorzio Per Gli Studi Uni | Procedimento per la preparazione di un tessuto non tessuto in fibroinadi seta. |
| ATE420671T1 (de) | 2001-10-25 | 2009-01-15 | Univ Connecticut | Fibroinzusammensetzungen und verfahren zu deren herstellung |
| EP1459728A4 (en) | 2001-11-29 | 2005-04-20 | Nat Inst Of Agrobio Sciences | EMULSIFIER AND METHOD FOR ITS MANUFACTURE |
| WO2004062697A2 (en) | 2003-01-07 | 2004-07-29 | Tufts University | Silk fibroin materials and use thereof |
| US7060260B2 (en) | 2003-02-20 | 2006-06-13 | E.I. Du Pont De Nemours And Company | Water-soluble silk proteins in compositions for skin care, hair care or hair coloring |
| US7193038B2 (en) | 2003-02-28 | 2007-03-20 | National Institute Of Agrobiological Sciences | Extraction and utilization of cell growth-promoting peptides from silk protein |
| US7115388B2 (en) | 2003-03-14 | 2006-10-03 | National Institute Of Agrobiological Sciences | Production of functional polypeptides originating from silk protein and use thereof |
| US20050196370A1 (en) | 2003-03-18 | 2005-09-08 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye |
| WO2005012606A2 (en) | 2003-04-10 | 2005-02-10 | Tufts University | Concentrated aqueous silk fibroin solution and use thereof |
| US20050202097A1 (en) | 2004-03-12 | 2005-09-15 | Melbj Holdings, Llc, Florida | Lubricant for the ocular surface |
| EP1609801A1 (en) | 2004-06-25 | 2005-12-28 | Technische Universität München | Proteins of natural origin and materials made therefrom |
| JP4896017B2 (ja) | 2004-07-31 | 2012-03-14 | バイオグランド シーオー エル ティー ディー | 脳疾患または頭脳機能改善のための組成物 |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| CA2624667C (en) | 2005-10-05 | 2018-01-09 | Commonwealth Scientific And Industrial Research Organisation | Silk proteins containing coiled coil region |
| WO2007130364A2 (en) | 2006-05-01 | 2007-11-15 | Riolan Technologies, Inc. | Compositions, methods, and kits for treating dry eye |
| WO2008109138A1 (en) | 2007-03-07 | 2008-09-12 | Grune Guerry L | Spf compositions |
| KR20100029217A (ko) * | 2007-05-29 | 2010-03-16 | 트러스티즈 오브 터프츠 칼리지 | 음파 처리를 이용한 실크 피브로인 겔화 방법 |
| CN101194666A (zh) | 2007-11-28 | 2008-06-11 | 吴江市方霞企业信息咨询有限公司 | 蚕蛹丝素蛋白功能性食品 |
| WO2009088119A1 (en) | 2008-01-07 | 2009-07-16 | Bioleaders Corporation | Composition for preventing or treating dry eye syndrome comprising poly-gamma-glutamic acid |
| EP2403551A4 (en) | 2009-03-04 | 2014-02-26 | Tufts College | FIBROIN SILK SYSTEMS FOR ANTIBIOTIC DELIVERY |
| WO2010123947A2 (en) | 2009-04-20 | 2010-10-28 | Allergan, Inc. | Silk fibroin hydrogels and uses thereof |
| NZ596932A (en) | 2009-06-05 | 2014-04-30 | Allergan Inc | Artificial tears and therapeutic uses |
| WO2011008842A2 (en) | 2009-07-14 | 2011-01-20 | Trustees Of Tufts College | Electrospun silk material systems for wound healing |
| US9603971B2 (en) | 2010-03-05 | 2017-03-28 | Trustees Of Tufts College | Silk-based ionomeric compositions |
| US8309689B2 (en) | 2010-05-20 | 2012-11-13 | Taipei Medical University | High yield dialysis-free process for producing organosoluble regenerated silk fibroin |
| EP2582360A4 (en) | 2010-06-17 | 2014-01-22 | Tufts University Trustees Of Tufts College | OPTICAL SILK PARTICLES AND USES THEREOF |
| WO2012170655A1 (en) | 2011-06-07 | 2012-12-13 | Cornell University | Silk compositions and methods of using same |
| CN102860969A (zh) | 2011-07-07 | 2013-01-09 | 刘畅 | 一种大豆眼霜 |
| WO2013126799A1 (en) | 2012-02-22 | 2013-08-29 | Trustees Of Tufts College | Compositions and methods for ocular delivery of a therapeutic agent |
| US9056063B2 (en) | 2012-03-13 | 2015-06-16 | James E. Hanson | Natural sunscreen composition |
| US20150079012A1 (en) | 2012-04-20 | 2015-03-19 | Trustees Of Tufts College | Silk fibroin-based personal care compositions |
| US20140235554A1 (en) | 2013-02-12 | 2014-08-21 | Brian Lawrence | Ophthalmic formulation derived from silk protein |
| KR20230021768A (ko) * | 2013-03-15 | 2023-02-14 | 트러스티즈 오브 터프츠 칼리지 | 저분자량 실크 조성물 및 안정화 실크 조성물 |
| AU2014240170B2 (en) | 2013-03-15 | 2018-05-17 | Patheon Softgels Inc. | Silk-based capsules |
| CN103225126B (zh) * | 2013-05-14 | 2014-10-22 | 浙江大学 | 丝素/海藻酸钠复合纳米纤维支架的制备方法 |
| CN103239707A (zh) | 2013-05-22 | 2013-08-14 | 江苏紫石化工科技有限公司 | 治疗近视的滴眼液 |
| JP6775751B2 (ja) | 2013-09-30 | 2020-10-28 | エボルブド バイ ネイチャー， インコーポレイテッド | 絹タンパク質断片組成物及びそれから製造された物品 |
| AU2014353110B2 (en) | 2013-11-19 | 2018-05-10 | Cornell University | Tissue scaffold materials for tissue regeneration and methods of making |
| ES2781114T3 (es) * | 2014-08-20 | 2020-08-28 | Silk Tech Ltd | Composición proteica derivada de fibroína |
| US10758645B2 (en) | 2014-12-17 | 2020-09-01 | Tufts University | Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair |
| US11242367B2 (en) * | 2016-08-12 | 2022-02-08 | Silk Technologies, Ltd. | Silk-derived protein for treating inflammation |
-
2015
- 2015-08-20 ES ES15833824T patent/ES2781114T3/es active Active
- 2015-08-20 US US14/831,473 patent/US9394355B2/en active Active
- 2015-08-20 EP EP15833824.4A patent/EP3182985B1/en active Active
- 2015-08-20 DK DK15833824.4T patent/DK3182985T3/da active
- 2015-08-20 CA CA2994222A patent/CA2994222C/en active Active
- 2015-08-20 AU AU2015305386A patent/AU2015305386B2/en active Active
- 2015-08-20 HU HUE15833824A patent/HUE048702T2/hu unknown
- 2015-08-20 KR KR1020177007589A patent/KR102539012B1/ko active IP Right Grant
- 2015-08-20 SG SG11201704010UA patent/SG11201704010UA/en unknown
- 2015-08-20 JP JP2017529599A patent/JP6632161B2/ja active Active
- 2015-08-20 CN CN201580056923.1A patent/CN107105724B/zh active Active
- 2015-08-20 WO PCT/US2015/046141 patent/WO2016029034A1/en active Application Filing
-
2016
- 2016-07-15 US US15/212,086 patent/US9907836B2/en active Active
-
2018
- 2018-03-05 US US15/912,295 patent/US10471128B2/en active Active
-
2019
- 2019-11-11 US US16/680,186 patent/US11045524B2/en active Active
-
2021
- 2021-06-28 US US17/360,674 patent/US11890328B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2781114T3 (es) | 2020-08-28 |
| AU2015305386A1 (en) | 2017-04-06 |
| JP6632161B2 (ja) | 2020-01-22 |
| CA2994222C (en) | 2020-09-08 |
| DK3182985T3 (da) | 2020-04-06 |
| EP3182985A4 (en) | 2018-05-23 |
| US11890328B2 (en) | 2024-02-06 |
| US20220054596A1 (en) | 2022-02-24 |
| US10471128B2 (en) | 2019-11-12 |
| US11045524B2 (en) | 2021-06-29 |
| AU2015305386B2 (en) | 2020-03-05 |
| JP2017527612A (ja) | 2017-09-21 |
| US20160331815A1 (en) | 2016-11-17 |
| CN107105724A (zh) | 2017-08-29 |
| EP3182985A1 (en) | 2017-06-28 |
| EP3182985B1 (en) | 2020-01-08 |
| KR102539012B1 (ko) | 2023-05-31 |
| CN107105724B (zh) | 2021-02-26 |
| KR20170041275A (ko) | 2017-04-14 |
| CA2994222A1 (en) | 2016-02-25 |
| WO2016029034A1 (en) | 2016-02-25 |
| US20200171131A1 (en) | 2020-06-04 |
| US9394355B2 (en) | 2016-07-19 |
| US20180193429A1 (en) | 2018-07-12 |
| SG11201704010UA (en) | 2017-06-29 |
| US20160096878A1 (en) | 2016-04-07 |
| US9907836B2 (en) | 2018-03-06 |
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| ZA201704464B (en) | Composition | |
| GB201403561D0 (en) | Composition | |
| GB201414555D0 (en) | Composition | |
| GB201410493D0 (en) | Composition | |
| GB201420628D0 (en) | Composition | |
| GB201415483D0 (en) | Composition | |
| GB201404390D0 (en) | Composition | |
| GB201403550D0 (en) | Composition | |
| GB201402648D0 (en) | Composition | |
| GB201502355D0 (en) | Composition | |
| GB201414371D0 (en) | Protein modification | |
| GB201421660D0 (en) | Composition | |
| GB201412797D0 (en) | Proteins | |
| GB201412649D0 (en) | Proteins | |
| GB201412648D0 (en) | Proteins | |
| GB201412646D0 (en) | Proteins |