HUE047705T2 - Ivabradin-hidroklorid új polimorfja és eljárás elõállítására - Google Patents
Ivabradin-hidroklorid új polimorfja és eljárás elõállításáraInfo
- Publication number
- HUE047705T2 HUE047705T2 HUE14160639A HUE14160639A HUE047705T2 HU E047705 T2 HUE047705 T2 HU E047705T2 HU E14160639 A HUE14160639 A HU E14160639A HU E14160639 A HUE14160639 A HU E14160639A HU E047705 T2 HUE047705 T2 HU E047705T2
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- ivabradine hydrochloride
- new polymorph
- polymorph
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000416A ITMI20130416A1 (it) | 2013-03-19 | 2013-03-19 | Nuovo polimorfo del cloridrato di ivabradina e metodo per la sua preparazione |
IT000684A ITMI20130684A1 (it) | 2013-04-24 | 2013-04-24 | Nuovo polimorfo del cloridrato di ivabradina e metodo per la sua preparazione |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE047705T2 true HUE047705T2 (hu) | 2020-05-28 |
Family
ID=50280314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE14160639A HUE047705T2 (hu) | 2013-03-19 | 2014-03-19 | Ivabradin-hidroklorid új polimorfja és eljárás elõállítására |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2781509B2 (hu) |
ES (1) | ES2773502T5 (hu) |
FI (1) | FI2781509T4 (hu) |
HR (1) | HRP20200300T4 (hu) |
HU (1) | HUE047705T2 (hu) |
PL (1) | PL2781509T5 (hu) |
SI (1) | SI2781509T2 (hu) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104829530A (zh) * | 2015-04-23 | 2015-08-12 | 扬子江药业集团北京海燕药业有限公司 | 一种无定型盐酸伊伐布雷定及其制备方法 |
CN107056706B (zh) * | 2015-12-21 | 2020-05-05 | 江苏恒瑞医药股份有限公司 | 一种用于制备盐酸伊伐布雷定α晶型的方法 |
CN108947905B (zh) * | 2018-09-21 | 2021-01-08 | 浙江燎原药业股份有限公司 | 一种制备盐酸伊伐布雷定ε晶型的方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2681862B1 (fr) | 1991-09-27 | 1993-11-12 | Adir Cie | Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent. |
FR2868777B1 (fr) | 2004-04-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
FR2882553B1 (fr) † | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2882555B1 (fr) * | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline gamma du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2891827B1 (fr) | 2005-10-11 | 2007-12-28 | Servier Lab | Forme cristalline deltad du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2891826B1 (fr) | 2005-10-11 | 2007-12-28 | Servier Lab | Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
EP2097383B1 (en) | 2006-11-30 | 2012-02-08 | Cadila Healthcare Limited | Process for preparation of ivabradine hydrochloride |
PT2471780E (pt) * | 2007-05-30 | 2015-02-24 | Ind Swift Lab Ltd | Sais oxalato de ivabradina cristalinos e seus polimorfos |
EP2534135A2 (en) | 2010-02-12 | 2012-12-19 | KRKA, D.D., Novo Mesto | Novel forms of ivabradine hydrochloride |
WO2012025940A1 (en) | 2010-08-25 | 2012-03-01 | Cadila Healthcare Limited | Polymorphic form of ivabradine hydrochloride and process for preparation thereof |
WO2013017582A1 (en) | 2011-08-02 | 2013-02-07 | Sandoz Ag | Acetone solvate of ivabradine hydrochloride |
EP2589594A1 (en) | 2011-11-04 | 2013-05-08 | Urquima S.A. | Ivabradine hydrochloride Form IV |
EP3156399A1 (en) | 2011-11-14 | 2017-04-19 | Cadila Healthcare Limited | Polymorphic forms of ivabradine hydrochloride |
CN103864690B (zh) | 2014-01-06 | 2016-09-14 | 北京莱瑞森医药科技有限公司 | 伊伐布雷定盐酸盐的s晶型、其制备方法和药物组合物 |
IN201641022049A (hu) | 2016-06-28 | 2017-12-29 |
-
2014
- 2014-03-19 EP EP14160639.2A patent/EP2781509B2/en active Active
- 2014-03-19 SI SI201431493T patent/SI2781509T2/sl unknown
- 2014-03-19 HR HRP20200300TT patent/HRP20200300T4/hr unknown
- 2014-03-19 PL PL14160639.2T patent/PL2781509T5/pl unknown
- 2014-03-19 HU HUE14160639A patent/HUE047705T2/hu unknown
- 2014-03-19 ES ES14160639T patent/ES2773502T5/es active Active
- 2014-03-19 FI FIEP14160639.2T patent/FI2781509T4/fi active
Also Published As
Publication number | Publication date |
---|---|
ES2773502T3 (es) | 2020-07-13 |
SI2781509T1 (sl) | 2020-04-30 |
SI2781509T2 (sl) | 2023-10-30 |
HRP20200300T1 (hr) | 2020-06-12 |
EP2781509A1 (en) | 2014-09-24 |
HRP20200300T4 (hr) | 2023-09-15 |
FI2781509T4 (fi) | 2023-09-07 |
EP2781509B1 (en) | 2019-11-27 |
ES2773502T5 (es) | 2023-11-30 |
PL2781509T5 (pl) | 2023-09-25 |
EP2781509B2 (en) | 2023-06-14 |
PL2781509T3 (pl) | 2020-05-18 |
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