HUE047705T2 - Ivabradin-hidroklorid új polimorfja és eljárás elõállítására - Google Patents

Ivabradin-hidroklorid új polimorfja és eljárás elõállítására

Info

Publication number
HUE047705T2
HUE047705T2 HUE14160639A HUE14160639A HUE047705T2 HU E047705 T2 HUE047705 T2 HU E047705T2 HU E14160639 A HUE14160639 A HU E14160639A HU E14160639 A HUE14160639 A HU E14160639A HU E047705 T2 HUE047705 T2 HU E047705T2
Authority
HU
Hungary
Prior art keywords
preparation
ivabradine hydrochloride
new polymorph
polymorph
new
Prior art date
Application number
HUE14160639A
Other languages
English (en)
Inventor
Giuseppe Barreca
Marco Maria Gatti
Gianpiero Ventimiglia
Original Assignee
Chemo Res S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50280314&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE047705(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IT000416A external-priority patent/ITMI20130416A1/it
Priority claimed from IT000684A external-priority patent/ITMI20130684A1/it
Application filed by Chemo Res S L filed Critical Chemo Res S L
Publication of HUE047705T2 publication Critical patent/HUE047705T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
HUE14160639A 2013-03-19 2014-03-19 Ivabradin-hidroklorid új polimorfja és eljárás elõállítására HUE047705T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000416A ITMI20130416A1 (it) 2013-03-19 2013-03-19 Nuovo polimorfo del cloridrato di ivabradina e metodo per la sua preparazione
IT000684A ITMI20130684A1 (it) 2013-04-24 2013-04-24 Nuovo polimorfo del cloridrato di ivabradina e metodo per la sua preparazione

Publications (1)

Publication Number Publication Date
HUE047705T2 true HUE047705T2 (hu) 2020-05-28

Family

ID=50280314

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14160639A HUE047705T2 (hu) 2013-03-19 2014-03-19 Ivabradin-hidroklorid új polimorfja és eljárás elõállítására

Country Status (7)

Country Link
EP (1) EP2781509B2 (hu)
ES (1) ES2773502T5 (hu)
FI (1) FI2781509T4 (hu)
HR (1) HRP20200300T4 (hu)
HU (1) HUE047705T2 (hu)
PL (1) PL2781509T5 (hu)
SI (1) SI2781509T2 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104829530A (zh) * 2015-04-23 2015-08-12 扬子江药业集团北京海燕药业有限公司 一种无定型盐酸伊伐布雷定及其制备方法
CN107056706B (zh) * 2015-12-21 2020-05-05 江苏恒瑞医药股份有限公司 一种用于制备盐酸伊伐布雷定α晶型的方法
CN108947905B (zh) * 2018-09-21 2021-01-08 浙江燎原药业股份有限公司 一种制备盐酸伊伐布雷定ε晶型的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2681862B1 (fr) 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
FR2868777B1 (fr) 2004-04-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2882553B1 (fr) 2005-02-28 2007-05-04 Servier Lab Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882555B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2891827B1 (fr) 2005-10-11 2007-12-28 Servier Lab Forme cristalline deltad du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2891826B1 (fr) 2005-10-11 2007-12-28 Servier Lab Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
EP2097383B1 (en) 2006-11-30 2012-02-08 Cadila Healthcare Limited Process for preparation of ivabradine hydrochloride
PT2471780E (pt) * 2007-05-30 2015-02-24 Ind Swift Lab Ltd Sais oxalato de ivabradina cristalinos e seus polimorfos
EP2534135A2 (en) 2010-02-12 2012-12-19 KRKA, D.D., Novo Mesto Novel forms of ivabradine hydrochloride
WO2012025940A1 (en) 2010-08-25 2012-03-01 Cadila Healthcare Limited Polymorphic form of ivabradine hydrochloride and process for preparation thereof
WO2013017582A1 (en) 2011-08-02 2013-02-07 Sandoz Ag Acetone solvate of ivabradine hydrochloride
EP2589594A1 (en) 2011-11-04 2013-05-08 Urquima S.A. Ivabradine hydrochloride Form IV
EP3156399A1 (en) 2011-11-14 2017-04-19 Cadila Healthcare Limited Polymorphic forms of ivabradine hydrochloride
CN103864690B (zh) 2014-01-06 2016-09-14 北京莱瑞森医药科技有限公司 伊伐布雷定盐酸盐的s晶型、其制备方法和药物组合物
IN201641022049A (hu) 2016-06-28 2017-12-29

Also Published As

Publication number Publication date
ES2773502T3 (es) 2020-07-13
SI2781509T1 (sl) 2020-04-30
SI2781509T2 (sl) 2023-10-30
HRP20200300T1 (hr) 2020-06-12
EP2781509A1 (en) 2014-09-24
HRP20200300T4 (hr) 2023-09-15
FI2781509T4 (fi) 2023-09-07
EP2781509B1 (en) 2019-11-27
ES2773502T5 (es) 2023-11-30
PL2781509T5 (pl) 2023-09-25
EP2781509B2 (en) 2023-06-14
PL2781509T3 (pl) 2020-05-18

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