HUE044011T2 - 1-[(2-bromofenil) szulfonil]-5-metoxi-3-[(4-metil-1-piperazinil)metil]-1H-indol dimezilát monohidrát aktív metabolitja és az aktív metabolit dimezilát dihidrát sója - Google Patents
1-[(2-bromofenil) szulfonil]-5-metoxi-3-[(4-metil-1-piperazinil)metil]-1H-indol dimezilát monohidrát aktív metabolitja és az aktív metabolit dimezilát dihidrát sójaInfo
- Publication number
- HUE044011T2 HUE044011T2 HUE14825443A HUE14825443A HUE044011T2 HU E044011 T2 HUE044011 T2 HU E044011T2 HU E14825443 A HUE14825443 A HU E14825443A HU E14825443 A HUE14825443 A HU E14825443A HU E044011 T2 HUE044011 T2 HU E044011T2
- Authority
- HU
- Hungary
- Prior art keywords
- methyl
- active metabolite
- dimesylate
- bromophenyl
- piperazinyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN4011CH2014 | 2014-08-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE044011T2 true HUE044011T2 (hu) | 2019-09-30 |
Family
ID=52345478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE14825443A HUE044011T2 (hu) | 2014-08-16 | 2014-10-20 | 1-[(2-bromofenil) szulfonil]-5-metoxi-3-[(4-metil-1-piperazinil)metil]-1H-indol dimezilát monohidrát aktív metabolitja és az aktív metabolit dimezilát dihidrát sója |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US10010527B2 (hu) |
| EP (1) | EP3180001B1 (hu) |
| JP (1) | JP6629322B2 (hu) |
| KR (1) | KR101938408B1 (hu) |
| CN (1) | CN106794170A (hu) |
| AP (1) | AP2017009752A0 (hu) |
| AU (1) | AU2014404000B2 (hu) |
| BR (1) | BR112017002921B1 (hu) |
| CA (1) | CA2957497C (hu) |
| CY (1) | CY1121393T1 (hu) |
| DK (1) | DK3180001T3 (hu) |
| EA (1) | EA031319B1 (hu) |
| ES (1) | ES2715113T3 (hu) |
| HR (1) | HRP20190446T1 (hu) |
| HU (1) | HUE044011T2 (hu) |
| IL (1) | IL250411B (hu) |
| LT (1) | LT3180001T (hu) |
| MX (1) | MX2017002045A (hu) |
| NZ (1) | NZ728907A (hu) |
| PL (1) | PL3180001T3 (hu) |
| PT (1) | PT3180001T (hu) |
| RS (1) | RS58575B1 (hu) |
| SG (1) | SG11201701106RA (hu) |
| SI (1) | SI3180001T1 (hu) |
| TR (1) | TR201903344T4 (hu) |
| WO (1) | WO2016027276A1 (hu) |
| ZA (1) | ZA201700915B (hu) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1326830A1 (en) | 2000-10-20 | 2003-07-16 | Biovitrum Ab | 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy |
| AU2003208711A1 (en) * | 2002-02-12 | 2003-09-04 | Akzo Nobel N.V. | 1-arylsulfonyl-3-substituted indole and indoline derivatives useful in the treatment of central nervous system disorders |
| KR100818508B1 (ko) * | 2002-11-28 | 2008-03-31 | 수벤 라이프 사이언시스 리미티드 | 세로토닌 수용체 친화력을 가지는 엔-아릴술포닐-3-치환인돌, 그 제조방법 및 그를 포함하는 약제학적 조성물 |
| KR100739987B1 (ko) * | 2002-12-18 | 2007-07-16 | 수벤 라이프 사이언시스 리미티드 | 세로토닌 수용체 친화력을 가지는 테트라사이클릭 3-치환인돌 |
| CA2674087A1 (en) * | 2007-02-16 | 2008-08-21 | Memory Pharmaceuticals Corporation | 6' substituted compounds having 5-ht6 receptor affinity |
| EA017154B1 (ru) * | 2007-10-26 | 2012-10-30 | Сувен Лайф Сайенсиз Лимитед | Аминоарилсульфонамидные соединения и их применение в качестве 5-нтлигандов |
-
2014
- 2014-10-20 PT PT14825443T patent/PT3180001T/pt unknown
- 2014-10-20 AP AP2017009752A patent/AP2017009752A0/en unknown
- 2014-10-20 SG SG11201701106RA patent/SG11201701106RA/en unknown
- 2014-10-20 CN CN201480081234.1A patent/CN106794170A/zh active Pending
- 2014-10-20 NZ NZ728907A patent/NZ728907A/en unknown
- 2014-10-20 KR KR1020177004616A patent/KR101938408B1/ko active IP Right Grant
- 2014-10-20 ES ES14825443T patent/ES2715113T3/es active Active
- 2014-10-20 MX MX2017002045A patent/MX2017002045A/es active IP Right Grant
- 2014-10-20 JP JP2017527993A patent/JP6629322B2/ja active Active
- 2014-10-20 LT LTEP14825443.6T patent/LT3180001T/lt unknown
- 2014-10-20 WO PCT/IN2014/000667 patent/WO2016027276A1/en active Application Filing
- 2014-10-20 EP EP14825443.6A patent/EP3180001B1/en active Active
- 2014-10-20 PL PL14825443T patent/PL3180001T3/pl unknown
- 2014-10-20 DK DK14825443.6T patent/DK3180001T3/en active
- 2014-10-20 HU HUE14825443A patent/HUE044011T2/hu unknown
- 2014-10-20 US US15/504,014 patent/US10010527B2/en active Active
- 2014-10-20 CA CA2957497A patent/CA2957497C/en active Active
- 2014-10-20 SI SI201431124T patent/SI3180001T1/sl unknown
- 2014-10-20 BR BR112017002921-9A patent/BR112017002921B1/pt active IP Right Grant
- 2014-10-20 TR TR2019/03344T patent/TR201903344T4/tr unknown
- 2014-10-20 AU AU2014404000A patent/AU2014404000B2/en active Active
- 2014-10-20 EA EA201790396A patent/EA031319B1/ru unknown
- 2014-10-20 RS RS20190286A patent/RS58575B1/sr unknown
-
2017
- 2017-02-02 IL IL250411A patent/IL250411B/en active IP Right Grant
- 2017-02-06 ZA ZA2017/00915A patent/ZA201700915B/en unknown
-
2019
- 2019-03-06 HR HRP20190446TT patent/HRP20190446T1/hr unknown
- 2019-03-08 CY CY20191100280T patent/CY1121393T1/el unknown
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