HUE038981T2 - Szulfatált poligulonsav poliszaccharidok vagy gyógyászatilag elfogadható sóik, eljárás azok elõállítására és alkalmazásuk - Google Patents

Szulfatált poligulonsav poliszaccharidok vagy gyógyászatilag elfogadható sóik, eljárás azok elõállítására és alkalmazásuk

Info

Publication number
HUE038981T2
HUE038981T2 HUE14819337A HUE14819337A HUE038981T2 HU E038981 T2 HUE038981 T2 HU E038981T2 HU E14819337 A HUE14819337 A HU E14819337A HU E14819337 A HUE14819337 A HU E14819337A HU E038981 T2 HUE038981 T2 HU E038981T2
Authority
HU
Hungary
Prior art keywords
preparation
method therefor
pharmaceutical salt
acid polysaccharide
polygulonic acid
Prior art date
Application number
HUE14819337A
Other languages
English (en)
Inventor
Jian Ding
Jing Ai
Yi Chen
Xun Huang
Original Assignee
Shanghai Inst Materia Medica Cas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica Cas filed Critical Shanghai Inst Materia Medica Cas
Publication of HUE038981T2 publication Critical patent/HUE038981T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HUE14819337A 2013-07-02 2014-07-02 Szulfatált poligulonsav poliszaccharidok vagy gyógyászatilag elfogadható sóik, eljárás azok elõállítására és alkalmazásuk HUE038981T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310275323.7A CN104277130A (zh) 2013-07-02 2013-07-02 一种硫酸酯化聚古洛糖酸多糖或其可药用盐及其制备方法和用途

Publications (1)

Publication Number Publication Date
HUE038981T2 true HUE038981T2 (hu) 2018-12-28

Family

ID=52143111

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14819337A HUE038981T2 (hu) 2013-07-02 2014-07-02 Szulfatált poligulonsav poliszaccharidok vagy gyógyászatilag elfogadható sóik, eljárás azok elõállítására és alkalmazásuk

Country Status (20)

Country Link
US (1) US10058566B2 (hu)
EP (1) EP3018147B1 (hu)
JP (2) JP6757249B2 (hu)
KR (1) KR102258569B1 (hu)
CN (2) CN104277130A (hu)
AU (1) AU2014286711B2 (hu)
BR (1) BR112015032849B1 (hu)
CA (1) CA2916749C (hu)
DK (1) DK3018147T3 (hu)
EA (1) EA028655B1 (hu)
ES (1) ES2674976T3 (hu)
HK (1) HK1220984A1 (hu)
HU (1) HUE038981T2 (hu)
MX (1) MX2016000043A (hu)
PL (1) PL3018147T3 (hu)
PT (1) PT3018147T (hu)
SG (1) SG11201510717SA (hu)
TR (1) TR201809674T4 (hu)
WO (1) WO2015000411A1 (hu)
ZA (1) ZA201509353B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104277130A (zh) * 2013-07-02 2015-01-14 中国科学院上海药物研究所 一种硫酸酯化聚古洛糖酸多糖或其可药用盐及其制备方法和用途
CN107904240A (zh) * 2017-12-04 2018-04-13 辽东学院 一种抗肝癌细胞转移的抑制剂组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3228231A1 (de) * 1982-07-28 1984-02-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Arzneimittel, calciummischsalze von polymeren, anionischen carbonsaeuren und/oder schwefelsaeureestern, verfahren zu ihrer herstellung und ihre verwendung
JPH0625304A (ja) * 1992-07-06 1994-02-01 Higeta Shoyu Co Ltd ガラクトサミン重合体硫酸化物及び該物質を 含有する抗ウイルス剤
CN1132209A (zh) 1995-03-27 1996-10-02 青岛海洋大学 一种新药多聚甘露糖醛酸硫酸盐
GB2317182B (en) 1996-09-11 2000-11-01 Johnson & Johnson Medical Sulfated polysaccharides and uses thereof in medical treatment
CN1473836A (zh) 2003-08-04 2004-02-11 中国海洋大学 还原端1位为羧基的古罗糖醛酸寡糖及其衍生物
CN1213071C (zh) * 2003-11-25 2005-08-03 中国海洋大学 一种古糖酯及其制备方法和应用
JP4897310B2 (ja) 2006-02-28 2012-03-14 理研食品株式会社 L−グルロン酸金属塩又はd−マンヌロン酸金属塩の製造方法
JP2008027767A (ja) 2006-07-21 2008-02-07 Aomori Prefecture 固体高分子電解質膜及び燃料電池
CN101691410B (zh) * 2009-09-18 2011-12-28 中国海洋大学 一种具有防治胰岛素抵抗作用的海洋寡糖铬配合物
CN102892421A (zh) 2010-03-10 2013-01-23 伊诺沃生物公司 用于治疗代谢病症的包含葡甘露聚糖、黄原胶和藻酸盐的食物
CN102743409B (zh) 2012-06-18 2013-11-20 中国海洋大学 聚甘露糖醛酸丙酯硫酸盐在制备抗甲型h1n1流感病毒药物中的应用
CN104277130A (zh) * 2013-07-02 2015-01-14 中国科学院上海药物研究所 一种硫酸酯化聚古洛糖酸多糖或其可药用盐及其制备方法和用途

Also Published As

Publication number Publication date
WO2015000411A1 (zh) 2015-01-08
US10058566B2 (en) 2018-08-28
CA2916749A1 (en) 2015-01-08
HK1220984A1 (zh) 2017-05-19
EP3018147B1 (en) 2018-05-23
BR112015032849A2 (pt) 2020-05-12
CA2916749C (en) 2021-03-09
AU2014286711B2 (en) 2018-05-10
JP2016523301A (ja) 2016-08-08
JP2019090056A (ja) 2019-06-13
SG11201510717SA (en) 2016-01-28
EA028655B1 (ru) 2017-12-29
ZA201509353B (en) 2017-08-30
DK3018147T3 (en) 2018-07-23
KR20160029817A (ko) 2016-03-15
TR201809674T4 (tr) 2018-07-23
ES2674976T3 (es) 2018-07-05
KR102258569B1 (ko) 2021-05-28
CN105358582B (zh) 2018-09-21
MX2016000043A (es) 2016-05-31
EA201690123A1 (ru) 2016-07-29
BR112015032849B1 (pt) 2021-09-14
JP6772318B2 (ja) 2020-10-21
US20160367591A1 (en) 2016-12-22
EP3018147A4 (en) 2017-04-05
PT3018147T (pt) 2018-07-17
EP3018147A1 (en) 2016-05-11
PL3018147T3 (pl) 2018-10-31
JP6757249B2 (ja) 2020-09-16
AU2014286711A1 (en) 2016-02-04
CN105358582A (zh) 2016-02-24
CN104277130A (zh) 2015-01-14

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