HK1206329A1 - Phenol derivative, method of preparing same, and pharmaceutical application of same - Google Patents

Phenol derivative, method of preparing same, and pharmaceutical application of same

Info

Publication number
HK1206329A1
HK1206329A1 HK15106764.4A HK15106764A HK1206329A1 HK 1206329 A1 HK1206329 A1 HK 1206329A1 HK 15106764 A HK15106764 A HK 15106764A HK 1206329 A1 HK1206329 A1 HK 1206329A1
Authority
HK
Hong Kong
Prior art keywords
same
phenol derivative
pharmaceutical application
preparing
preparing same
Prior art date
Application number
HK15106764.4A
Other languages
Chinese (zh)
Inventor
張晨
李芳琼
黃安邦
雷鳴
王健民
魏用剛
鄧炳初
Original Assignee
Sichuan Haisco Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Haisco Pharmaceutical Co Ltd filed Critical Sichuan Haisco Pharmaceutical Co Ltd
Publication of HK1206329A1 publication Critical patent/HK1206329A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/573—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/14—Compounds containing azido groups with azido groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/47—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/18—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C43/196—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
HK15106764.4A 2013-05-10 2015-07-15 Phenol derivative, method of preparing same, and pharmaceutical application of same HK1206329A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201310170656 2013-05-10
CN201310369466 2013-08-22
PCT/CN2014/077051 WO2014180327A1 (en) 2013-05-10 2014-05-08 Phenol derivative, method of preparing same, and pharmaceutical application of same

Publications (1)

Publication Number Publication Date
HK1206329A1 true HK1206329A1 (en) 2016-01-08

Family

ID=51866730

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15106764.4A HK1206329A1 (en) 2013-05-10 2015-07-15 Phenol derivative, method of preparing same, and pharmaceutical application of same

Country Status (3)

Country Link
CN (1) CN104507898B (en)
HK (1) HK1206329A1 (en)
WO (1) WO2014180327A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108069833B (en) * 2016-11-15 2020-11-06 四川海思科制药有限公司 Benzocyclo-ring derivatives, preparation method and medical application thereof
CN112724001B (en) * 2019-10-28 2022-12-13 鲁南制药集团股份有限公司 Ivabradine chiral intermediate compound
CN114249652A (en) * 2020-09-25 2022-03-29 天地恒一制药股份有限公司 Phenol derivative and application thereof in medicine
WO2022161312A1 (en) 2021-01-28 2022-08-04 天地恒一制药股份有限公司 Phenol derivative and application thereof in medicaments
CN116063163A (en) * 2022-12-23 2023-05-05 上海毕臣生化科技有限公司 Preparation method of 7- (benzyloxy) -2,4,5, 6-tetrahydro-1H-cyclobutadiene [ f ] indene-1-one

Also Published As

Publication number Publication date
CN104507898B (en) 2017-11-21
WO2014180327A1 (en) 2014-11-13
CN104507898A (en) 2015-04-08

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Legal Events

Date Code Title Description
CHRG Changes in the register

Free format text: ADDITION OF INVENTOR:

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230508