HUE035171T2 - Afukozilált CD 20 antitest kombinált terápiája CD79b antitest gyógyszerkonjugátumával - Google Patents
Afukozilált CD 20 antitest kombinált terápiája CD79b antitest gyógyszerkonjugátumával Download PDFInfo
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- HUE035171T2 HUE035171T2 HUE14724662A HUE14724662A HUE035171T2 HU E035171 T2 HUE035171 T2 HU E035171T2 HU E14724662 A HUE14724662 A HU E14724662A HU E14724662 A HUE14724662 A HU E14724662A HU E035171 T2 HUE035171 T2 HU E035171T2
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- Prior art keywords
- antibody
- cd79b
- seq
- antibodies
- affinity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Claims (2)
- I« Übtegezomabi rákos megbetegeáes .teeÄbban tbrfenó tehasználzsta az amkCD79b-> va'v t' \B \1\1 \1 < ! *„note <" v'Siu'.ifuiVv’, s\" a. ??» < Π ' <v:,\^t a említed üD?9h átesést gybgyszet-tetgngátamábao egy búMÁ79b,v2b5 amely magáhan foglalja a SbQ 1D hlö: te szerinti kteoyöláne variábilis tettem ás a SbQ 1D NÔ: 70 szerinti nebóziáne variábilis tennem. 2, <>bte«um»Mb az 1,. igénypóat szerite használata rákos megbetegedés kezeieséhen, kmtemaha ·./ aat-C i>"óm\it oed*\b-\lM\f Cte’te smote p\ng>\<\'5 komngamma^d, azzal jellemezve, begs vg\ vagy több :O\abbs mm·. -maatete?, kemmerapkm \agy mkdlenev h-tmatmag regyéte \agx >t:g,rkî. zdes m <dkahuaa,aMa tetül jniOg'k tetei,mk m b\en batáatsyagek hatását, Sx Oblteitebrnte az L vagy 2- i gény pen t szerinti basztsálaía rates ttegbetegedés kezelésében, kombinálva az anti~f;D79b''MC-'Ve-'i?AB-'MMAls Cf>79b antitest gyógyszer kottegáitnnávsl, azzal jabetnezve, hogy a szóhan íetgá rák agy ÖteÖ-at ezpresszálá rák, 7, temnstnzstmah a 7, fgánypónt szerinti használata rák kezelésében, tentetsálva az CP'te ;>!"« rP"te M* \eP\bMM\l' Cite»·' ,mKte g>og>'' -érd mtegaunnm ai, ,ο/,η jellemezve, hegy a szóhan forge CDSO-at ezpresszálá rákltetena vagy linrforoás leukémia,.
- 5, Készítmény rákos megbetegedés kezelésében történő felhasználásra, anndy ohmonoamaten v ttetmnt anlt-CU7yb-M.C-ve-PAR-MMA B <?í)79b ani kést gyógyszer -temugamtsnS tartalmam altéi az arteCÖ?0h antitest az emhtett CD?9b ambest gyógyszer-koningstamban egv haMA.79b.v21f, amely magában tbgialjs a SEQ Jö Nkk ék szedte konnyufane vámtól ts tement és a SEQ lü NO: 70 szerinti ttehézlánc variábilis dotnent n kés, ítmény te-m, ntegbetegeóe\ kezektevm tértene íd has .-mélám a ne 5. 'genypomn sk megfelelőért., azzal jellemezve, begy egy vagy több további más olyan contested kemoterápiás vagy rákellenes hatóanyag, vegytllet vagy sugárkezelés Is alkalmazásra kérők amelyek fokozzák az. Ilyen hatóanyagok hatását,
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361818821P | 2013-05-02 | 2013-05-02 |
Publications (1)
Publication Number | Publication Date |
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HUE035171T2 true HUE035171T2 (hu) | 2018-05-02 |
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ID=50733021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE14724662A HUE035171T2 (hu) | 2013-05-02 | 2014-04-30 | Afukozilált CD 20 antitest kombinált terápiája CD79b antitest gyógyszerkonjugátumával |
Country Status (27)
Country | Link |
---|---|
US (4) | US20140356352A1 (hu) |
EP (1) | EP2992016B1 (hu) |
JP (1) | JP6306154B2 (hu) |
KR (1) | KR101824311B1 (hu) |
CN (1) | CN105189558A (hu) |
AR (1) | AR096183A1 (hu) |
AU (1) | AU2014261454B2 (hu) |
BR (1) | BR112015027309A2 (hu) |
CA (1) | CA2908658C (hu) |
DK (1) | DK2992016T3 (hu) |
ES (1) | ES2653424T3 (hu) |
HK (1) | HK1213575A1 (hu) |
HR (1) | HRP20171897T1 (hu) |
HU (1) | HUE035171T2 (hu) |
IL (1) | IL242163B (hu) |
LT (1) | LT2992016T (hu) |
MX (1) | MX359964B (hu) |
MY (1) | MY181960A (hu) |
NO (1) | NO3080382T3 (hu) |
NZ (1) | NZ713745A (hu) |
PL (1) | PL2992016T3 (hu) |
PT (1) | PT2992016T (hu) |
RS (1) | RS56688B1 (hu) |
RU (1) | RU2670971C9 (hu) |
SG (1) | SG11201509009WA (hu) |
SI (1) | SI2992016T1 (hu) |
WO (1) | WO2014177615A2 (hu) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI2247620T1 (sl) * | 2008-01-31 | 2016-09-30 | Genentech, Inc. | Protitelesa proti CD79b in imunokonjugati in postopki za uporabo |
AU2015320678B2 (en) * | 2014-09-23 | 2021-07-22 | Genentech, Inc. | Method of using anti-CD79b immunoconjugates |
US20170315132A1 (en) * | 2016-03-25 | 2017-11-02 | Genentech, Inc. | Multiplexed total antibody and antibody-conjugated drug quantification assay |
US20180140703A1 (en) * | 2016-11-18 | 2018-05-24 | The Regents Of The University California | Tumor radiosensitization with antibody conjugates |
CA3045944A1 (en) | 2016-12-07 | 2018-06-14 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
WO2019200322A1 (en) * | 2018-04-13 | 2019-10-17 | Genentech, Inc. | Stable anti-cd79b immunoconjugate formulations |
WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
MX2021008760A (es) | 2019-01-28 | 2021-08-24 | Tuojie Biotech Shanghai Co Ltd | Anticuerpo anti-cd79b, fragmento de union a antigeno del mismo y uso farmaceutico del mismo. |
CN115666704A (zh) | 2019-12-13 | 2023-01-31 | 比奥拉治疗股份有限公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
CN112094345B (zh) * | 2020-06-01 | 2024-01-05 | 普众发现医药科技(上海)有限公司 | 可应用于肿瘤细胞捕获的小鼠抗免疫球蛋白关联βCD79b的单克隆抗体 |
MX2023001163A (es) * | 2020-07-27 | 2023-02-22 | Tuojie Biotech Shanghai Co Ltd | Conjugado de farmaco anticuerpo anti-cd79b, metodo de preparacion y uso farmaceutico del mismo. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6922984B2 (en) * | 2003-08-27 | 2005-08-02 | Valero Refining Company - California | Heat recovery circuit |
CN102373214B (zh) * | 2003-11-05 | 2014-07-09 | 罗氏格黎卡特股份公司 | 具有增加的Fc受体结合亲和性和效应子功能的CD20抗体 |
ES2382627T3 (es) * | 2004-06-29 | 2012-06-12 | B.R.A.H.M.S Gmbh | Nuevos anticuerpos monoclonales estimuladores o bloqueadores de la tiroides, secuencias peptídicas que corresponden a sus regiones variables, y sus usos en medicina diagnóstica, preventiva y terapéutica |
SI2176296T1 (sl) * | 2007-07-16 | 2012-05-31 | Genentech Inc | Protitelesa proti CD b in imunokonjugati in postopki za uporabo |
SI2247620T1 (sl) * | 2008-01-31 | 2016-09-30 | Genentech, Inc. | Protitelesa proti CD79b in imunokonjugati in postopki za uporabo |
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2014
- 2014-04-30 KR KR1020157034237A patent/KR101824311B1/ko active IP Right Grant
- 2014-04-30 DK DK14724662.3T patent/DK2992016T3/en active
- 2014-04-30 LT LTEP14724662.3T patent/LT2992016T/lt unknown
- 2014-04-30 SI SI201430518T patent/SI2992016T1/en unknown
- 2014-04-30 AU AU2014261454A patent/AU2014261454B2/en active Active
- 2014-04-30 BR BR112015027309A patent/BR112015027309A2/pt not_active Application Discontinuation
- 2014-04-30 ES ES14724662.3T patent/ES2653424T3/es active Active
- 2014-04-30 US US14/266,443 patent/US20140356352A1/en not_active Abandoned
- 2014-04-30 HU HUE14724662A patent/HUE035171T2/hu unknown
- 2014-04-30 RU RU2015151454A patent/RU2670971C9/ru active
- 2014-04-30 CA CA2908658A patent/CA2908658C/en active Active
- 2014-04-30 NZ NZ713745A patent/NZ713745A/en unknown
- 2014-04-30 MY MYPI2015703902A patent/MY181960A/en unknown
- 2014-04-30 PT PT147246623T patent/PT2992016T/pt unknown
- 2014-04-30 AR ARP140101794A patent/AR096183A1/es unknown
- 2014-04-30 SG SG11201509009WA patent/SG11201509009WA/en unknown
- 2014-04-30 EP EP14724662.3A patent/EP2992016B1/en active Active
- 2014-04-30 PL PL14724662T patent/PL2992016T3/pl unknown
- 2014-04-30 JP JP2016511053A patent/JP6306154B2/ja active Active
- 2014-04-30 CN CN201480023250.5A patent/CN105189558A/zh active Pending
- 2014-04-30 WO PCT/EP2014/058827 patent/WO2014177615A2/en active Application Filing
- 2014-04-30 MX MX2015015091A patent/MX359964B/es active IP Right Grant
- 2014-04-30 RS RS20171301A patent/RS56688B1/sr unknown
- 2014-12-03 NO NO14820742A patent/NO3080382T3/no unknown
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2015
- 2015-10-19 IL IL242163A patent/IL242163B/en active IP Right Grant
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2016
- 2016-02-11 HK HK16101476.3A patent/HK1213575A1/zh unknown
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2017
- 2017-11-09 US US15/808,795 patent/US20180133315A1/en not_active Abandoned
- 2017-12-06 HR HRP20171897TT patent/HRP20171897T1/hr unknown
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2018
- 2018-08-10 US US16/101,203 patent/US20180344848A1/en not_active Abandoned
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2020
- 2020-12-18 US US17/127,697 patent/US20210138065A1/en not_active Abandoned
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