HU9603237D0 - Kristalline hydrochloride of (r)-(-)-2-{n-[4-(1,1-dioxydo-3-oxo-2,3-dihydro-benzisothiazo-2-yl)-butyl]-amino-methyl}-chromane - Google Patents
Kristalline hydrochloride of (r)-(-)-2-{n-[4-(1,1-dioxydo-3-oxo-2,3-dihydro-benzisothiazo-2-yl)-butyl]-amino-methyl}-chromaneInfo
- Publication number
- HU9603237D0 HU9603237D0 HU9603237A HUP9603237A HU9603237D0 HU 9603237 D0 HU9603237 D0 HU 9603237D0 HU 9603237 A HU9603237 A HU 9603237A HU P9603237 A HUP9603237 A HU P9603237A HU 9603237 D0 HU9603237 D0 HU 9603237D0
- Authority
- HU
- Hungary
- Prior art keywords
- dioxydo
- benzisothiazo
- kristalline
- chromane
- dihydro
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19543478A DE19543478A1 (de) | 1995-11-22 | 1995-11-22 | Kristallines Hydrochlorid von {(R)-(-)-2- N-[4-(1,1-Dioxido-3-oxo-2,3-dihydrobenzisothiazol-2-yl)-buytl]-aminomethyl}-chroman |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9603237D0 true HU9603237D0 (en) | 1997-01-28 |
HUP9603237A2 HUP9603237A2 (hu) | 1998-01-28 |
HUP9603237A3 HUP9603237A3 (en) | 1998-12-28 |
Family
ID=7778081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9603237A HUP9603237A3 (en) | 1995-11-22 | 1996-11-22 | Crystalline hydrochloride of (r)-(-)-2-{n-[4-(1,1-dioxydo-3-oxo-2,3-dihydro-benzisothiazo-2-yl)-butyl]-amino-methyl}-chromane, process for the preparation thereof and pharmaceutical compositions containing them |
Country Status (32)
Country | Link |
---|---|
US (1) | US5830908A (hu) |
EP (1) | EP0775704B1 (hu) |
JP (1) | JPH09143180A (hu) |
KR (1) | KR970027079A (hu) |
CN (1) | CN1086703C (hu) |
AR (1) | AR004961A1 (hu) |
AT (1) | ATE201872T1 (hu) |
AU (1) | AU712922B2 (hu) |
BR (1) | BR9605646A (hu) |
CA (1) | CA2190700A1 (hu) |
CZ (1) | CZ289730B6 (hu) |
DE (2) | DE19543478A1 (hu) |
DK (1) | DK0775704T3 (hu) |
EE (1) | EE9600183A (hu) |
ES (1) | ES2159342T3 (hu) |
GR (1) | GR3036505T3 (hu) |
HU (1) | HUP9603237A3 (hu) |
IL (1) | IL119647A (hu) |
MX (1) | MX9605741A (hu) |
MY (1) | MY132473A (hu) |
NO (1) | NO307340B1 (hu) |
NZ (1) | NZ299780A (hu) |
PL (1) | PL317090A1 (hu) |
PT (1) | PT775704E (hu) |
RU (1) | RU2181723C2 (hu) |
SG (1) | SG44989A1 (hu) |
SI (1) | SI0775704T1 (hu) |
SK (1) | SK150096A3 (hu) |
TR (1) | TR199600930A2 (hu) |
TW (1) | TW449595B (hu) |
UA (1) | UA45338C2 (hu) |
ZA (1) | ZA969753B (hu) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5854217A (en) * | 1992-09-28 | 1998-12-29 | Bearsden Bio, Inc. | Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
EA030606B1 (ru) | 2006-05-04 | 2018-08-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Способы приготовления лекарственного средства, содержащего полиморфы |
KR101610005B1 (ko) * | 2007-08-17 | 2016-04-08 | 베링거 인겔하임 인터내셔날 게엠베하 | Fab 관련 질환의 치료에 사용하기 위한 푸린 유도체 |
PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
PE20100156A1 (es) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
EA031225B1 (ru) * | 2008-08-15 | 2018-12-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Ингибиторы дпп-4 для заживления ран |
EP2344195A2 (en) | 2008-09-10 | 2011-07-20 | Boehringer Ingelheim International GmbH | Combination therapy for the treatment of diabetes and related conditions |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
BRPI0923121A2 (pt) | 2008-12-23 | 2015-08-11 | Boehringer Ingelheim Int | Formas salinas de compostos orgânico |
TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
ES2760917T3 (es) | 2009-11-27 | 2020-05-18 | Boehringer Ingelheim Int | Tratamiento de pacientes diabéticos genotipificados con inhibidores DPP-IV como la linagliptina |
JP6034781B2 (ja) | 2010-05-05 | 2016-11-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 併用療法 |
EA201991014A1 (ru) | 2010-06-24 | 2019-09-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Лечение диабета |
US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
MX366629B (es) | 2011-07-15 | 2019-07-17 | Boehringer Ingelheim Int | Quinazolinas sustituidas, su preparación y su uso en composiciones farmacéuticas. |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP3685839A1 (en) | 2012-05-14 | 2020-07-29 | Boehringer Ingelheim International GmbH | Linagliptin for use in the treatment of albuminuria and kidney related diseases |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
US9526728B2 (en) | 2014-02-28 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Medical use of a DPP-4 inhibitor |
JP2019517542A (ja) | 2016-06-10 | 2019-06-24 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | リナグリプチンおよびメトホルミンの組合せ |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3901814A1 (de) | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
US5300523A (en) * | 1988-07-28 | 1994-04-05 | Bayer Aktiengesellschaft | Substituted aminomethyltetralins and their heterocyclic analogues |
DE4138756A1 (de) * | 1991-11-26 | 1993-05-27 | Troponwerke Gmbh & Co Kg | Kombination mit neuroprotektiver wirkung |
-
1995
- 1995-11-22 DE DE19543478A patent/DE19543478A1/de not_active Withdrawn
-
1996
- 1996-10-30 AR ARP960104981A patent/AR004961A1/es unknown
- 1996-11-11 PT PT96118043T patent/PT775704E/pt unknown
- 1996-11-11 AT AT96118043T patent/ATE201872T1/de not_active IP Right Cessation
- 1996-11-11 SI SI9630292T patent/SI0775704T1/xx unknown
- 1996-11-11 DE DE59607040T patent/DE59607040D1/de not_active Expired - Fee Related
- 1996-11-11 DK DK96118043T patent/DK0775704T3/da active
- 1996-11-11 EP EP96118043A patent/EP0775704B1/de not_active Expired - Lifetime
- 1996-11-11 ES ES96118043T patent/ES2159342T3/es not_active Expired - Lifetime
- 1996-11-14 AU AU71772/96A patent/AU712922B2/en not_active Ceased
- 1996-11-18 JP JP8322212A patent/JPH09143180A/ja not_active Withdrawn
- 1996-11-19 IL IL11964796A patent/IL119647A/xx not_active IP Right Cessation
- 1996-11-19 CA CA002190700A patent/CA2190700A1/en not_active Abandoned
- 1996-11-19 US US08/752,348 patent/US5830908A/en not_active Expired - Fee Related
- 1996-11-19 NZ NZ299780A patent/NZ299780A/en unknown
- 1996-11-20 PL PL96317090A patent/PL317090A1/xx unknown
- 1996-11-20 SG SG1996011319A patent/SG44989A1/en unknown
- 1996-11-20 TW TW085114226A patent/TW449595B/zh not_active IP Right Cessation
- 1996-11-21 KR KR1019960056088A patent/KR970027079A/ko not_active Application Discontinuation
- 1996-11-21 BR BR9605646A patent/BR9605646A/pt unknown
- 1996-11-21 ZA ZA969753A patent/ZA969753B/xx unknown
- 1996-11-21 EE EE9600183A patent/EE9600183A/xx unknown
- 1996-11-21 NO NO964950A patent/NO307340B1/no not_active IP Right Cessation
- 1996-11-21 MY MYPI96004849A patent/MY132473A/en unknown
- 1996-11-21 UA UA96114365A patent/UA45338C2/uk unknown
- 1996-11-21 MX MX9605741A patent/MX9605741A/es unknown
- 1996-11-21 SK SK1500-96A patent/SK150096A3/sk unknown
- 1996-11-21 CZ CZ19963428A patent/CZ289730B6/cs not_active IP Right Cessation
- 1996-11-22 RU RU96122395/04A patent/RU2181723C2/ru active
- 1996-11-22 TR TR96/00930A patent/TR199600930A2/xx unknown
- 1996-11-22 CN CN96114587A patent/CN1086703C/zh not_active Expired - Fee Related
- 1996-11-22 HU HU9603237A patent/HUP9603237A3/hu unknown
-
2001
- 2001-08-31 GR GR20010401365T patent/GR3036505T3/el not_active IP Right Cessation
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