HU195251B - Process for producing new antibioticum a 80190, derivatives and pharmaceutical compositions containing them - Google Patents
Process for producing new antibioticum a 80190, derivatives and pharmaceutical compositions containing them Download PDFInfo
- Publication number
- HU195251B HU195251B HU853911A HU391185A HU195251B HU 195251 B HU195251 B HU 195251B HU 853911 A HU853911 A HU 853911A HU 391185 A HU391185 A HU 391185A HU 195251 B HU195251 B HU 195251B
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- HU
- Hungary
- Prior art keywords
- antibiotic
- nrrl
- medium
- mono
- feed
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- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical class C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 1
- 229960004927 neomycin Drugs 0.000 description 1
- 201000005111 ocular hyperemia Diseases 0.000 description 1
- 229960002351 oleandomycin Drugs 0.000 description 1
- 235000019367 oleandomycin Nutrition 0.000 description 1
- 239000012044 organic layer Substances 0.000 description 1
- 238000004816 paper chromatography Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 229940056360 penicillin g Drugs 0.000 description 1
- 229940074571 peptostreptococcus anaerobius Drugs 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 239000002460 polyether antibiotic agent Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229940113115 polyethylene glycol 200 Drugs 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000013587 production medium Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- WYVAMUWZEOHJOQ-UHFFFAOYSA-N propionic anhydride Chemical compound CCC(=O)OC(=O)CC WYVAMUWZEOHJOQ-UHFFFAOYSA-N 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 229910052701 rubidium Inorganic materials 0.000 description 1
- IGLNJRXAVVLDKE-UHFFFAOYSA-N rubidium atom Chemical compound [Rb] IGLNJRXAVVLDKE-UHFFFAOYSA-N 0.000 description 1
- 229910001419 rubidium ion Inorganic materials 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
- BHRZNVHARXXAHW-UHFFFAOYSA-N sec-butylamine Chemical compound CCC(C)N BHRZNVHARXXAHW-UHFFFAOYSA-N 0.000 description 1
- 238000012807 shake-flask culturing Methods 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 230000000392 somatic effect Effects 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- 239000012485 toluene extract Substances 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 125000003774 valeryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 238000009333 weeding Methods 0.000 description 1
- 238000002424 x-ray crystallography Methods 0.000 description 1
- 229960003487 xylose Drugs 0.000 description 1
- 239000011667 zinc carbonate Substances 0.000 description 1
- 235000004416 zinc carbonate Nutrition 0.000 description 1
- 229910000010 zinc carbonate Inorganic materials 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/658,976 US4582822A (en) | 1984-10-09 | 1984-10-09 | Antibiotic A80190, pharmaceutical compositions containing same and method of use |
| US06/658,977 US4683204A (en) | 1984-10-09 | 1984-10-09 | Process for producing antibiotic A80190 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT39780A HUT39780A (en) | 1986-10-29 |
| HU195251B true HU195251B (en) | 1988-04-28 |
Family
ID=27097733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU853911A HU195251B (en) | 1984-10-09 | 1985-10-08 | Process for producing new antibioticum a 80190, derivatives and pharmaceutical compositions containing them |
Country Status (12)
-
1985
- 1985-10-07 PT PT81262A patent/PT81262B/pt not_active IP Right Cessation
- 1985-10-07 ES ES547644A patent/ES8609460A1/es not_active Expired
- 1985-10-07 GR GR852423A patent/GR852423B/el unknown
- 1985-10-08 IL IL76607A patent/IL76607A/xx not_active IP Right Cessation
- 1985-10-08 DK DK457485A patent/DK159684C/da active
- 1985-10-08 AT AT85307186T patent/ATE76645T1/de not_active IP Right Cessation
- 1985-10-08 DE DE8585307186T patent/DE3586120D1/de not_active Expired - Lifetime
- 1985-10-08 HU HU853911A patent/HU195251B/hu not_active IP Right Cessation
- 1985-10-08 NZ NZ213730A patent/NZ213730A/xx unknown
- 1985-10-09 CN CN198585108210A patent/CN85108210A/zh active Pending
-
1992
- 1992-07-21 SG SG748/92A patent/SG74892G/en unknown
- 1992-09-03 HK HK674/92A patent/HK67492A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK159684B (da) | 1990-11-19 |
| PT81262B (pt) | 1988-02-17 |
| ATE76645T1 (de) | 1992-06-15 |
| PT81262A (en) | 1985-11-01 |
| DK457485D0 (da) | 1985-10-08 |
| ES547644A0 (es) | 1986-07-16 |
| HUT39780A (en) | 1986-10-29 |
| IL76607A (en) | 1989-02-28 |
| IL76607A0 (en) | 1986-02-28 |
| NZ213730A (en) | 1989-01-06 |
| DK457485A (da) | 1986-04-10 |
| SG74892G (en) | 1992-10-02 |
| HK67492A (en) | 1992-09-11 |
| CN85108210A (zh) | 1986-12-03 |
| DE3586120D1 (de) | 1992-07-02 |
| GR852423B (enrdf_load_stackoverflow) | 1986-02-10 |
| ES8609460A1 (es) | 1986-07-16 |
| DK159684C (da) | 1991-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |