HU190391B - Cosmetic composition, particularly for skin regeneration - Google Patents

Abstract

1.0006-0.1% by weight of Roman camomile oil, 2.01% to 2.5% by weight of lavender resinoid, 3. 0.02 to 5.0% by weight of water as an active ingredient according to the invention. alcohol oak bark extract concentrate, 4. 0.04-5.0 wt.% aqueous lime pellet extract concentrate, 5. 0.02-5.0 wt.% aqueous walnut extract concentrate, and optionally 6. 0.0004-0. , 05% by weight of camomile oil, 7. 0.02-2.5% by weight of aqueous camomile extract concentrate, 8. 0.02-2.5% by weight of aqueous medical sage extract concentrate, 9. 0.02-2.5% % by weight of aqueous alcoholic willow bark extract concentrate, 10. 0.01-1.5% by weight of hops specific.

Description

BACKGROUND OF THE INVENTION The present invention relates to novel cosmetic compositions whose principal effect is the unexpected and rapid regeneration of skin and connective tissue. The main use is in the foot care for multiple applications, Sun ⁵ formulation of sunscreen effect and UVerithéma management, as well as the so-called problematic skins regeneration associated with the sport.

It is known that due to various environmental influences, in particular atmospheric effects, most people may be in a sensitive or irritated state. A large number of solutions for treating these symptoms are described in the literature.

In spite of the wide variety of known solutions, niche ¹⁵ would be a solution that would work simultaneously

I. a soothing and mild analgesic effect on the sensitized or irritated skin, ²⁰

II. especially for oily and particularly sensitive skin, it has a hardening and pore-tightening effect,

III. skin regenerating - skin nourishing, exfoliating, etc. effect

ARC. local blood circulation enhancing effect, 25

V. antiseptic or antimycotic effect, and

VI. slight antiperspirant effect.

It has now been found that, surprisingly, a combination of said effects is represented by a novel cosmetic composition which, in addition to the carriers and / or excipients commonly used in the preparation of the cosmetic compositions, comprises as active ingredient the total weight of the composition according to the invention.

1. 0,0006-0,1% by weight of Roman chamomile oil,

2. 0.01 to 2.5% by weight of lavender resinoid,

3. 0.02-5.0% by weight of water-alcoholic oak bark extract concentrate,

4. 0.04-5.0% by weight of an aqueous goose extract extract,

5. 0.02-5.0% by weight aqueous walnut leaf extract concentrate, optionally

6. 0.0004-0.05% by weight of chamomile oil, 45

7. 0.02 to 2.5% by weight of an aqueous concentrate of chamomile extract,

8. 0.02 to 2.5% by weight aqueous medicinal sage extract concentrate,

9. 0.02-2.5% by weight of water-alcoholic willow bark extract 50,

10. A mixture of 0.01-1.5% by weight of hops-specific, and additionally 60.0-95.0% by weight of ethanol-water (based on 40-75% by weight of ethanol). 55

Values given herein are pure substances for the two types of chamomile oil (Components 1 and 6), Lavender Resinoid (Component 2), and Hop-specific (Component 10) for the other 6 components. representing about 50% by weight of dry matter θθ. It should be noted that the dry matter content of the final compositions of the invention is less than the theoretical value (2 to 10% by weight), since more or less precipitation is to be expected during preparation and the precipitated material must be removed by filtration. The compositions of the invention may also be characterized by quantitative analysis of known active ingredients of herbs 5 and 9, which are as follows:

total flavonoids of azulene and kamazulene α-bisabolol total tannin 0.002% by weight <0.020% by weight <0.10% by weight <0.05% by weight

The drugs used as starting materials for the herbal complexes which are the active ingredients of the compositions of the invention are all known herbs, some of which are officially used in pharmacopoeia, others are widely used in folk medicine and cosmetics.

The most well-known of these is chamomile (see, for example, Issekutz B. "Pharmacology and Healing", pp. 550-551).

She.; published in Budapest in 1959 by Medicina), which has anti-inflammatory, soothing, anti-allergic, mild antiseptic and emollient properties. In particular, the main effect of oils is the anti-inflammatory property (ibid., P. 577). There is very little distinction about the Roman chamomile, although it is a popular herb in many countries, such as France, where it is officially recognized in the pharmacopoeia.

The walnut and sage aqueous extract is also the primary anti-inflammatory property. For lege artis teas (decoctions or infusions), walnut extract for skin disorders and dermatitis (see, for example, Pahlow M. "Das groBe Buch dér Heilpflanzen" 344.0; published by the Graph and Unzer GmbH in Munich in 1979), it is also used for compressing eye inflammation and facial wraps. An aqueous extract of sage is used in cosmetics for oily acne skin, and in folk medicine for the treatment of hemorrhoids and other rectal complaints. The astringent, disinfectant and haemostatic effect of the extract is also known (ibid. P. 145).

The liquorice of gooseberry is primarily used internally as an antispasmodic agent (see, for example, Braun, H., "Heilpflanzen-Lexikon für Árzte und Apotheker", 155.0; published in Stuttgart in 1974 by G. Fischer Verlag).

Oak and willow bark are high tannic acid drugs. The aqueous extract of oak bark is used for its astringent astringent effect. Its main fields of application are: treatment of dermatitis and burns, treatment of hemorrhoids and rectum, but also has a moderate antiperspirant effect. The willow bark extract is less commonly used, has a weak salicylic effect, and has a tincture of 96% vol. It is used in concentrations of 2% by weight for antirheumatic treatments. For both plants, reference may be made to Braun's book (p. 159).

In the case of lavender, the use of essential oil is known; It is used in refreshing, stimulating, invigorating and anti-rheumatic baths. Its water boiling is recommended for compressing. Oral use in hops is the most well-known, but its oily extract is a known biocosmetic active ingredient. With regard to these two plants, reference is made to the work already cited by Pahlow (213 and 174, 0).

190 391

It can be said yet that the 9 herbal main hatáshordozóit, the α-bisabolol, azulene of the tannins and flavonoids produced from natural or synthetic clean themselves apply cosmetics or medicinal active material of ^five. With regard to azulene and tannins, reference may be made to the work already cited by Issekutz. In the case of α-bisabolol, Fiedler Η. P. Reference is made to the book "Lexikon hoer Hilfsstofle für Pharmazie, Kosmetik und angewandte Gebiete" (Vol. 1, ¹⁰ , p. 320; published in Aulendorf in 1981 by Editio Cantor). There are several references to the use of flavonoids (see, for example, ¹⁵ Rote Liste 1977/78 published in Frankfurt am Main in 1978 by the Bundesverband dér Pharm. Industrie).

As for the extract from said plants, industrial előállításukról no accurate data, the aqueous extraction is mainly used in cosmetics and the people in the practice of medicine, in the form of infusion or decoction of Preparation ^20. In cosmetic practice, aqueous extracts are used in a concentration of 25-90% by weight, most often 30-60% by weight. Suitable values for oily extracts are 2 to 5, preferably 2 to 3% by weight. 25

The compositions of the invention, on the one hand, exhibit novel effects and, on the other hand, exhibit additional effects over known additive effects.

New effects or modes of application include:

- reducing foot pain and fatigue in foot care and eliminating so-called heavy foot problems.

- accelerating regeneration, exercising, reducing fatigue after exercising and exercising, and not having muscle fever, muscle aches and minor stretches,

- sunscreen properties based on unknown mechanism and action against special UV erythema,

- the immediate moisturizing effect of the treatment, followed by a prolonged treatment,

- reduction of skin sensitization following barrier incision,

- the prevention or effective treatment of swimming pool water infusions and dress injuries,

- Conditioning and regenerating effect on hair, scalp and so-called problem skin.

For the known effects specific to each component, unexpected efficacy was observed when using the compositions of the invention. Enhanced and synergistic effects include:

- a soothing effect of the same value as several known medicines, and

- regeneration of skin, subcutaneous connective tissue, including venous capillary wall,

- greater efficiency in warming-up athletes than previously used agents.

In addition to the results of cosmetic tests, the unexpected magnitude of these effects can be demonstrated by comparing the concentrations of known active ingredients responsible for the major effects with those commonly used in cosmetic practice. The results are shown in Table I. Table:

Table I

Active Ingredients Concentration (% by weight) cosmetics ordinary the In compositions according to the invention * f * b c d e azulene 0.02-0.05 0,002 0,002 0,002 0,002 0,002 0,002 a-bisabolol 0.05-1.0 0,005 0,005 0,005 0,005 0.01 0.02 Total tannin 0.15-0.45 0.05 0.12 0.05 0.10 0.10 0.10 összflavonoid 0.12 to 0.20 0.02 0.01 0.02 0.03 0.02 0.03

* Relative to active ingredient / ethanol-water mixture as carrier x markings a-f see below

From the data in the table it can be seen that the usual active substance concentrations used in cosmetic formulations are several times higher than those measured in the compositions of the invention. This percentage of 25% drug content is about 5-15 ten events ₅₅ times up. In the case of the most frequently used 0.1 to 10% by weight of active ingredient, the difference is more than two orders of magnitude. Determination of total tannic acid content is described in Ph.

Hg. VI, Volume 1, p. (published by Medicina θθ in Budapest, 1967), Definition of Total Flavonoid Content, Phytochemical Note, p.250. (published by SOTE in Budapest, 1981) and the determination of α-bisabolol and azulene content is essentially as described in MSZ 9262-81.

The compositions according to the invention are thus present in an amount of from 0.04% to 25%, preferably from 0.1% to 10% by weight, in conventional cosmetic formulations such as creams, liquid emulsions, solutions (shampoos, baths, drops and lotions) and spray or aerosol formulations. can be made. A very advantageous use is in the form of a scarf, wherein the usual carrier material, fabric or paper is soaked with a stock solution of the composition.

Different concentrations are used in the compositions of the invention. Thus, the active ingredient content of creams and liquid emulsions is expedient3

190,391 en 0.04-5% w / w. The concentration range is 0.1-5% by weight in shampoos, 0.1-12.5% by weight in hair treatments, and 0.1-25% by weight in bath compositions, and 0.4-25% by weight in balneotherapy preparations. The active ingredient concentration of the solutions and sprays for application as well as of the stock solutions applied to the tissue generally ranges from 0.2 to 25% by weight.

The active ingredient combinations forming the active ingredient of the cosmetic compositions of the invention are mixtures of aqueous and / or alcoholic, preferably ethanolic, extracts of various plants. The mixtures are brown translucent aqueous herbal solutions with a characteristic herbal odor, containing about 40% by volume of alcohol and having a pH of 4 to 6 in a 1: 1 aqueous dilution. The solutions may be stored for one year in a closed container protected from light at a temperature between 5 ° C and 25 ° C. At longer storage, minimal sedimentation occurs. Therefore, filtration prior to processing into the final product is desirable.

The physical properties of some of the active ingredients in herb combinations are as follows:

A) Mandatory active substances:

1. Roman chamomile oil (Anthemis nobilis, flos)

Characteristic odor, fresh dark green, light-brown, light-moving oil when standing, especially when exposed to light. The viscosity is 8 ± 4 mPa.s. The pH of its aqueous tail (1 + 50) is between 4-5.

2. Lavender Resinoid (Lavendula officinalis, herba)

It has a characteristic lavender scent of dark green, jam-like paste. The pH of its aqueous tail (1 + 50)

It is between 3-4,5.

3. Alcoholic extract of oak bark (Quercus robur, cortex)

It is a neutral, slightly alcoholic, dark black product. Initially, it moves from a dense stream, standing up to a solid consistency, easy to crumble. Its aqueous suspension (1: 1) has a pH of 4-5. It has a fresh solids content of 50% by weight and may concentrate on standing.

4. Concentrated water goose pimple (Potentilla anserina, herba)

It has a characteristic brownish-black color with a characteristic aroma that is reminiscent of cooked salt. It is dense, jam-like. Aqueous dilution (1: 1) has a pH of 4-5. It has a fresh solids content of 45-55% by weight.

5. Walnut leaf extract concentrate (Juglans regia, folium)

Slightly sweetish scent with a black, tarry paste. Aqueous dilution (1: 1) has a pH of 4-6. It has a fresh solids content of 45-55% by weight.

B) Optional active substances.

6. Chamomile oil (Matricaria chamomilla.flos)

It has a characteristic, slightly chamomile or sunflower-scented, fresh dark blue oil, which is green and then brownish, easy-to-move, especially during direct light. The viscosity is 5 ± 3 mPa.s. The pH of its aqueous tail (1 + 50)

It is between 4.5 and 5.5.

7. Aqueous Camomile Extract Concentrate (Matricaria chamomilla flos)

Slightly sweetish scent, dark brown with a dense flow. Aqueous dilution (1: 1) has a pH of 4-5.5. It has a fresh solids content of 45-55% by weight.

8. Aqueous medicinal sage extract concentrate (Salvia officinalis folium)

It has a characteristic lace jelly / lace black smell reminiscent of a black-brown consistency. The pH of its aqueous mixture (1: 1)

It is between 4.5 and 5.5. It has a fresh solids content of 45-55% by weight.

9. Liquorice extract (Salíx alba, cortex)

It is an indifferent, slightly alcoholic, dark brownish-black, dense, flowing product. The pH of its aqueous mixture (1: 1) is between 3.5 and 5.5. Its dry matter content is approx. 45-55% by weight, may be concentrated on standing.

10. Hops-specific (Humulus lupulus. Stobulus)

Slightly sweet-scented, dark brown in color, crude resinous, but highly soluble. The pH of its aqueous tail (1 + 50) is between 3.5 and 5.5. Water content 1-2, max. 15% by volume.

The following materials are prepared as follows:

1. Roman chamomile oil

The essential oil extracted from the flowering stem of Antomis nobilis L. by steam distillation is Roman chamomile oil. The aforementioned plant does not occur in Hungary in the wild, but its cultivated variant is grown. The oil must not contain pesticides in detectable quantities by gas chromatography. The plant material was treated with steam at a pressure of 300-400 kPa in a stainless steel pan with a humidifier and a cooling coil, maintaining a distillation rate of 80-100 liters per hour and collecting the essential oil in glass Florentini vessels.

2. Lavender Resinoid

The lavender resinoid is obtained by extraction from the annual flowering stalk of Lavendula vera L. after evaporation and drying of the essential oil.

After drying, the dried plant is first subjected to extraction with dichloromethane, and the extract is evaporated to a concentrate which, if not used immediately, is then cooled, after cooling, in 10 volumes of 96% by volume ethanol.

3. Wet alcohol extract of oak bark

The extract is from Quercus robur L., Quercus pedunculata Ehrh., Quercus petrae L. or Quercus sessiliflore Salisb. from bark by extraction with 50% by volume ethanol.

Preferably, the crust is soaked in 50% v / v aqueous ethanol for 12 hours after grinding, the alcoholic solution is separated, then filtered and then concentrated to a dry matter content of almost 50%.

Only bark can be collected from trees that are less than 10 cm thick and have not yet formed a cork bark.

4. Water goose pimple extract

Potentilla anserina L. is dried, above the fold

190 391 portions (stems, leaves and flowers) are soaked in 10 times water, preferably heated to 55 ° C. After maintaining this temperature for four hours, the resulting extract was filtered and concentrated to a pressure of 6 kPa. For reasons of economy, the soaking ^{5 is} repeated three times. The filtrates thus obtained are also evaporated.

5. Wet walnut extract

Dried leaves of Juglans regia L. are soaked in a 10-fold amount of water, the water is preferably heated to 55 ^{to 10} "C. After maintaining this temperature for four hours, the resulting aqueous extract was filtered and concentrated to a pressure of 6 kPa. For economic reasons, the soaking is repeated three times.

After filtering the resulting eluates are concentrated ^{to 15} also.

6-7. Chamomile oil and aqueous camomile extract concentrate

Preparing said agents preferably utilizes a stainless camomile essential oil of which ²⁰ to 20% by weight and at least bisabololtartalom the chamazulene content of at least 3%.

The chamomile used as starting material may contain up to 10% by weight of non-toxic and non-toxic weeds, and of non-toxic and non-essential oil weeds. The essential oil must not contain any pesticide in detectable quantities by gas chromatography.

The production of the essential oil is carried out in substantially the same manner as the Roman camomile oil.

Parallel to the water vapor distillation, hot water condensing on the bottom of the distillation vessel is collected, and mechanical impurities are removed therefrom by filtration and the filtrate is preferably concentrated at a pressure of about 35% by weight to about 50% by weight.

The resulting jam was then dissolved in ethanol (96% by volume), cooled for 24 hours, and the precipitated polysaccharides and proteins removed by filtration. This is how we swallow the aqueous chamomile extract.

8. Aqueous medical sage extract concentrate

An aqueous broth of Salvia of Ticinalis L. leaf blossom is prepared for 4 hours, then the broth is filtered to remove coagulating polysaccharides and proteins and finally concentrated under vacuum at 50 ° C to 50% by weight of dry matter.

9. Water-Alcoholic Willow Bark Extract Concentrate

It is obtained from the bark of Salix caprea L. by extraction with 50% by volume ethanol.

Preferably, the crust is soaked in 50% aqueous ethanol for 12 hours after grinding, and the ethanol solution is filtered separately and concentrated to about 50% dry weight.

It is advisable to prepare the extract just before use because it is moldy due to its relatively high sugar content.

10. Hop-specific

It is obtained from a pseudorandum plant called a hop cone, in substantially the same manner as described for the preparation of lavender resinoid.

The active compound combinations are prepared by diluting each of the 5 to 10 components each time with a sufficient concentration of aqueous ethanol. The solutions thus obtained are filtered or decanted and mixed in descending order. After blending, the ethanol content of the combination is suitably adjusted to 40% by weight and purified by passing through a filter press. The combination is then refrigerated for 6 days and finally filtered to "mirror".

For the active compound combinations, six of the most typical and at the same time the most effective formulations are specifically described. In the embodiments, these combinations will also be referred to as the a-f index.

Designation of combinations

Starting materials (weight *) the b c d e f Roman chamomile oil 0.1 0.05 0.07 0.15 0.10 0.05 Lavendula-resinoid 2.0 4.0 1.5 2.0 1.0 2.0 Oak bark extract concentrate 4.0 8.0 3.0 4.0 2.0 4.0 Goose pimple extract concentrate 6.0 2.0 5.0 6.0 4.0 8.0 Walnut extract concentrate 4.0 8.0 3.0 4.0 2.0 4.0 camomile - - - - 0.03 0.05 Chamomile extract concentrate - - - - 2.0 4.0 Medical sage extract concentrate - - 2.0 4.0 2.0 4.0 Willow bark extract concentrate _ · - - 2.0 4.0 Hops-specific - - 1.0 2.0 1.0 2.0 Ethanol 46.5% by weight 83.90 - 84.43 - 83.87 - Ethanol 50.0% by weight * - - - 77.85 - - Ethanol 56.0% by weight * - 67.95 - - - 67.90

The active compound combinations prepared as described above are then processed with commercially available cosmetic carriers and / or adjuvants, depending on the nature of the cosmetic compositions of the present invention.

The choice of carriers and / or excipients for the preparation of compositions is based on the use of non-sensitizing substances or formulation combinations and the provision of a pH value of 5 to 7 which is most favorable to the skin.

The most versatile creams used primarily for skin and connective tissue regeneration, in addition to 0.004 to 5% by weight of the active ingredient, contain quality and quantity depending on

190 391 carriers and / or excipients for the indication for which the cream is intended. However, most preferred are semi-fat, i.e., medium fat (about 30% by weight), hydrating, high in water (55-60% by volume) and low in alcohol (<4% by volume), 4.5-6%. Creams containing a solubilizing agent and / or trace elements which promote the absorption of the active ingredient. Liquid emulsions have a similar composition, with a lower dry matter content, of course. In the preparation of creams and emulsions, it is advantageous to first mix the active compound combination with a suitable solubilizing agent, then to mix the fragrance (s), and to add the resulting mixture at a certain temperature to the already gelling emulsion.

Another highly preferred form of treatment is the regenerating foam and soothing baths, which have a particularly good refreshing, invigorating and soothing effect. In preparing these, in addition to the 0.1 to 10% by weight of the active compound combination according to the invention, the surfactants added to the composition are chosen to have the lowest possible skin sensitizing effect and, on the other hand, to produce an optimal detergent activity. With the right additive, we also provide the greasing and preservative effect.

In the case of so-called balneotherapy, it is advisable to give a concentration of active ingredient of between 0.4 and 25% by weight.

Special formulations include shawls, sprays, aerosols and solutions for brushing. They have the common feature that the active compound combination according to the invention is present in a relatively high concentration of 0.2-25% by weight and that the alcohol, preferably ethanol, also has a high content, most often 15-40% by weight. The main additives for dressing stock, spray and paintbrushes, stabilizing and solubilizing agents, and coating and adhering glycerol may also be present, but may also contain preservatives. Another preferred formulation is the so-called aerosol foam, which contains additives necessary for the preparation of the product, preferably cetyl alcohol and sorbitan-polyoxyethylene-lauric ester, as well as a 1: 1 mixture of 12/114 propellants.

The novel scarf is advantageous in that it allows effective treatment of skin complaints around the anus during work or travel. The treatment stock solution is applied to paper or textiles of appropriate quality. The spray provides a comfortable, quick and painless option for the treatment of sensitive shin areas. In addition to its regenerative effect, aerosol foam is a special tool for soothing and reducing inflammation, and its application is also painless. Preparations for application are relatively concentrated. They have an active ingredient content of 0.5-40% by weight and can be formulated in a variety of forms (solution, drop, etc.).

Shampoo and hair conditioner are the two recommended products for hair and scalp care. The medicinal shampoos preferably contain from 0.1 to 5% by weight, and the cures from 0.1 to 12.5% by weight of herbal compositions. For shampoos, amphoteric-anionic surfactant detergent combinations with thickening, preservative and solubilizing additives are most preferred. Hair conditioners contain, in addition to a small amount of detergent, thickeners and additives to enhance the shine, smoothness and manageability of the hair.

A crucial advantage of the cosmetic compositions of the invention is the complex cosmetic efficacy, the well-controlled manufacturing technology and the natural origin of the active ingredients.

The invention is further illustrated by the following embodiments. In the examples, the total amount of active ingredients is expressed as the combined weight of the active ingredients and aqueous ethanol. In this mode of administration, the total active ingredient content may be from 2% to 50% by weight of the total composition.

1-6. Examples - Preparation of skin regenerating creams

The creams are made up of three phases, so-called phases A, B and C. The components of each phase are tabulated.

Phase A, i.e. the fatty phase components are melted at 70-75 water bath to ²⁵ ° C.

During the preparation of the phase B, i.e. the aqueous phase, the soluble additives are dissolved in a mixture of water and other solvent (s) used, and the temperature of the solution is adjusted to 72-77 ° C.

³⁰ AC phase material, i.e., the freshly-filtered active substance, fragrance compositions and the solubilizing agent are separately mixed.

Double-walled container mixer 72-77 'C phase B was added with stirring to 70-75 ° C of the layer ^35, and the resulting mixture was stirred for 5 minutes without cooling. Thereafter, the mixture is gradually cooled while continuing stirring. When the system temperature is close to 50 ° C, phase C is added with stirring. Finally, stirring is continued until it has cooled to 25-30 ° C.

Components Serial number of examples (% by weight) I. 2. 3. 4. 5. 6.

Phase A:

Stearyl alcohol I

White beeswax 3

Wool grease 3

C8-12 fatty acid triglyceride 3 6 cn J ^ei

White Vaseline 6

Glycerol Monostearate - Rate _B ^{* s * 8} '

Liquid paraffin 12 2

Solid paraffin Polyoxyoxyethylene sorbitan monolaurate containing 20 mol of ethylene oxide Cetyl alcohol Poly (oxyethylene) fatty acid ester θθ Stearin - 7

Isopropyl myristate - 8

Decyl oleic acid 2-octyldodecanol Phase B:

Propylene Glycol 4.5 3.8 θθ Glycerol 86% -5

610

5-8

4.5

2 4

- 6 8

- 2-5 3.8 4.5

14

-6 /

190 391

components Serial number of examples Components The sequence number of examples (crowd%) First Second Third 4th 5th 6th (% by weight) 7. 8th 9th 10th Distilled water 53 54.7 50.5 49.5 55.4 58.7 Phase A: sorbic 0.1 0.1 0.1 0.1 0.1 0.1 5 Polyoxyethylene (5) stearyl stearate 4 - - - Potassium sorbate 0.1 0.1 0.1 0.1 0.1 0.1 Poly (oxyethylene) -ceto stearyl alcoholic Phase C: where ether ^L Herb- combination 5 ^r * 5 * 10 * 10 * 5 2 ^b Triglycerides _of C8-C12 fatty acids - 14 12 20 moles of ethylene oxide Stearin 0.2 - - - containing poly (oxy) 10 Isopropyl myristate 5 7 - - ethylene) sorbitan Lauryl tetraglycol ether-O-phosphor 3 3.5 monodeát acid methyl ester 45 moles of ctilcn oxide Liquid paraffin 7 2 2 containing glycerin 1 Cetyl alcohol 2.5 - poly (ethyl glycol) - wool grease 3 - - oxy szlcarát 15 Diethyl ether containing 20 moles of ethylene oxide 30 moles of ethylene oxide sorbitan monostearate containing poly (oxy) 0.5 Phase B: of ethylene (-glicerin- Propylene glycol 3.8 - 3 3 monolaurate Glycerol 3 lllatkompozíció 0.3 0.3 0.3 0.3 0.1 0.1 Distilled water C-phase additive: 72.31 72.3 58.65

0.15 0.5 0.6

- 0.04 0.2 0.25

7-10. Examples - For the production of skin regenerating milks.

The milk (liquid emulsions) is prepared from two main (A, B) and two or three additive phases (D and optionally C and D). The composition of each phase is indicated.

7-8. s. Example recipe is prepared by a hot process. The technological specification is that the materials of the A phase, i.e. the fat phase, are melt-melted at about 70 ° C with stirring. In parallel, the B phase, i.e. the aqueous phase, is prepared by mixing the "cold" distilled water with propylene glycol or glycerol. Optionally (Example 8), the carboxyvinyl copolymer (additive phase) is further swollen cold and dissolved therein. Subsequently, the temperature of the combined phase is adjusted to about 72 ° C and then mixed with the gaseous phase with stirring. Depending on the model, intensive crushing (homogenization) is applied for 5 to 10 minutes, after which, optionally (Example 8), an aqueous solution of sodium hydroxide (Phase D) is added. The emulsion is then cooled at constant speed with constant stirring. The additive phase, i.e. the herbal combination, is added to the emulsion at a temperature of about 50 ° C. Finally, stirring was continued until cooled to 28-30 ° C.

9-10. s. Exemplary recipe is prepared by a cold process such that the carboxyvinyl copolymer (Phase C) is dissolved in small portions of the triglyceride of C8-C12 fatty acids in small doses and then mixed with the A, i.e. fatty phase. In parallel, the constituents of the B phase, i.e. the aqueous phase (distilled water and propylene glycol), are mixed. The finished phases are worked up with vigorous stirring for 10-20 minutes and then the aqueous sodium hydroxide solution (additive phase D) is added to the system with slow stirring. Thereafter the herb complex (additive phase E) is added to the emulsion, which is also thoroughly mixed.

Data Phase D: Sodium hydroxide Additive Phase E: Herbal combination

10 * ²⁵

11-16. Examples - Preparation of foam bath concentrate and bath bath concentrate:

Spin concentrates are generally prepared from 4, in some cases 3 (Example 16) phases. Phase 30 A is prepared by mixing the components in that order. Then, the B phase, the fragrance composition and the solubilisate of the degreasing agent are added and mixed thoroughly. The next phase (C) is the active compound 35 combination. The addition is followed by another stirring of about 5 minutes. In some cases (Examples 11-15), there is a fourth phase, usually an aqueous solution of sodium lauryl ether sulfate, which is also mixed with the system.

Component (% by weight)

11th

The sequence of examples is 12. 13. 14. 15.

16th

20

Phase A:

Kókuszzsírsavamidpropil betaine (30% - 20 ^os 20)

Propylene glycol ether sulfosuccinate - - 45 (40%)

Ammonium lauryl ether sulfate _ _Λ Coconut fatty acid dieta-. .

⁵⁰ nolamid ^{1 1}

Preparation of alkyl ether sulphate and pearlescent 3 5 3 Preparation of 450 molar polyethylene glycol _____ 2 monostearate

Quaternary lanolin.

alcohol

Glycerin - - - - - 1.5

Distilled water 31 17.9 11 17.9 19 51.5

Phase B:

Ethoxylated alkylphenol and 2-ethylhexenoic acid. ,,. . . . .

polyethylene glycol- ^{1 1.5 l 1.5 l} ester

Polyethylene glycol-7-glyceryl monococco-2 3 3 3 5 65 ^a '

-7190 391

I

Phase C:

Herbal «combination ³

Phase D:

Sodium lauryl ether sulfate (30%) Propylene glycol ether sulfosuccinate (40%)

20 '.15 * 10 * 5 ^b

35 45

17-20. Examples - Preparation of Conditioning Shampoos

Shampoos for hair and scalp care preparation method meets fűrdőkoncentrátumoknak except that the aqueous solution is heated to ₁₅ kókuszzsír- acid amide propyl betaine at 70 ° C and in certain cases (18-20. Examples) dissolved in intense mixing the thickening agent, the poly (oxyethylene) -6000 distearate, and also hot and with stirring was added ₂ q other components of the A-phase and B-phase, the fragrance composition solubilisate, then phase C (the herbal combination), and finally phase D, an aqueous solution of sodium lauryl ether sulfate or propylene glycol ether sulfosuccinate. Each stage ₂₅ zist mixed thoroughly after the application.

Components (% by weight)

The sequence of examples is 17. 18. 19. 20.

Phase A:

Coconut fatty acid amide propyl betaine (30%)

Polyoxyethylene-6000-Distearate Propylene glycol ether sulfosuccinate (40%)

Coconut fatty acid diethanolamide

Distilled water

Phase B:

animal composition mole ethylene oxide polyoxyethylene sorbitan monooleate

Phase C:

herbal Combination

Phase D:

Sodium lauryl ether sulfate (30%) Propylene glycol ether sulfosuccinate (40%)

20 20 20 17 - 0.2 0.5 0.5 - 10 - - 3 2 - 1 31.3 47.1 43.8 45.8 0.2 0.2 0.2 0.2 0.5 0.5 0.5 0.5 ^5d 5 ' 10 ' * 10 40 15 - - 25 25

21-24. Examples - Preparation of regenerative hair wraps

The use of hair wraps is linked to shampoos. Higher compared to the shampoo for drug concentration and longer treatment times (preferred to have from 15 to 30 minutes) can significantly enhance the sag resistance effec- ^50.

They are prepared by cold swelling and dissolving hydroxyethylene cellulose (phase A) at 30,000 mPa.s in small aliquots of distilled water with vigorous stirring. In some cases (Examples 21 and 22), the B phase materials are melted in parallel at 70 ° C, and then the C phase is heated while heating, in which case water and glycerol are added in one case (Example 23). In a mixture of 60, dissolve the citric acid and the cetrimonium chloride. Then warmly add C to Phase B, then gel (Phase A) and finally herb combination (D). All phases are thoroughly mixed in the system.

Components The number of examples is (% by weight) 21. 22. 23. 24.

Phase A:

Hydroxyethyl cellulose 3 2.5 2 2.5 Distilled water 5 5 5 5 Phase B: Glyceryl monostearate-palmitate 4 4 - - Lauryl alcohol poly (oxyethylene) ether 2 2 - - Phase C: Distilled water 58.5 69.2 69.7 83.5 Glycerol - - 10 - Citric acid 0.5 0.3 0.3 Cetyl trimethyl ammonium chloride 2 3 3 4 Phase D: Herbal combination * 25 15 = 10 ^b 5 '

25-32. Examples - Preparation of scarves, sprays, brushes and balneotherapies

The products can be prepared by mixing the components. The order of mixing is recommended according to the recipe list. In some cases, potassium sorbate and urea (Examples 25 and 28, 31 and 32) are dissolved in distilled water with stirring. Most of the formulations (Nos. 25-30) are for topical treatment, the last two recipes (Examples 31 and 32) being so-called balneotherapy formulations, which can be versatile. Their main effects are refreshing, soothing, coaching and regenerating. For the sanitary napkin, wipe the solution on a cloth or paper.

Components (% by weight) Serial number of examples 25th 26th 27th 28th 29th 30th 31st 32nd Gyógynövénykom- bináció I0 ¹ * 20 * 30 * 15 * 20 25 50 · 40 ' Ethanol 96% 15 18 15 12 17 20 20 24 Glycerol 10 12 15 10 12 12 - - Distilled water 64.9 50 40 62.9 51 43 28 31 Potassium sorbate 0.1 - - 0.1 - - - - Urea - - - - - - 2 5

Claims

Claims (7)

Claims Medicinal herb-containing cosmetic composition, in particular for skin regeneration, in which the liquid, solid or gaseous carriers and / or excipients customarily used in the preparation of cosmetic compositions are used in an amount up to 100% by weight, preferably vegetable or animal fats, water, glycerin. or alcohols and emulsifiers, dispersants and / or wetting agents, especially ethylene oxide condensates of fatty acids, fatty alcohols or fatty acid esters as excipients, and 60-95% by weight of the composition in an amount of from 40% to 75% by weight of the composition. a mixture of water, characterized in that, based on the total weight of the composition, 1. 0.0006-0.1% by weight of Roman chamomile oil, 2. 0.01 to 2.5% by weight of lavender resinoid, 3. 0.02-5.0% by weight of water-alcoholic oak bark extract concentrate, 190 391. 8. 0.02-2.5% by weight * aqueous medicinal sage extract concentrate, 9. 0.02-2.5 wt.% Aqueous alcoholic willow bark extract concentrate, 10. 0.01-1.5 wt.% * Hop-specific. The composition of claim 1 in the form of a cream or liquid emulsion, wherein the carrier is a vegetable or animal fat. 4. 0.04-5.0% by weight aqueous goose pimple extract concentrate, 5. 0.02-5.0% by weight aqueous walnut leaf extract concentrate, optionally 6. 0.0004-0.05 weight * chamomile oil, 7. An aqueous concentrate of 0.02% to 2.5% by weight of chamomile extract, and the excipient is a condensate of ethylene oxide, in particular an emulsifier, preferably a fatty acid ester, characterized in that it has a total content of 0.04% to 5.0%. 5 the third form habfurdőkoncentrátum, ülőfurdőkoncentrátum, hair pack or conditioning shampoo composition according to claim 1, wherein the carrier is water and the excipients with emulsifying, dispersing and wetting agent, with plate ¹⁰ with reference to the total active ingredient content of from 0.1 to 12.5 parts by weight *. A composition according to claim 1 in the form of a machine concentrate, spray, habaerosol or brush for a sanitary napkin, wherein the carrier ^{15 is} water and optionally glycerol, characterized in that it has a total active ingredient content of 0.2-25% by weight.