HU172167B - Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov - Google Patents

Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov

Info

Publication number
HU172167B
HU172167B HU76ME00002006A HUME002006A HU172167B HU 172167 B HU172167 B HU 172167B HU 76ME00002006 A HU76ME00002006 A HU 76ME00002006A HU ME002006 A HUME002006 A HU ME002006A HU 172167 B HU172167 B HU 172167B
Authority
HU
Hungary
Prior art keywords
bracket
oxasolo
pyridines
substituted
producing new
Prior art date
Application number
HU76ME00002006A
Other languages
English (en)
Hungarian (hu)
Inventor
Norman P Jensen
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HU172167B publication Critical patent/HU172167B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72Polycyclic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU76ME00002006A 1975-07-29 1976-07-28 Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov HU172167B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/600,169 US4011326A (en) 1975-07-29 1975-07-29 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents

Publications (1)

Publication Number Publication Date
HU172167B true HU172167B (hu) 1978-06-28

Family

ID=24402575

Family Applications (1)

Application Number Title Priority Date Filing Date
HU76ME00002006A HU172167B (hu) 1975-07-29 1976-07-28 Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov

Country Status (14)

Country Link
US (1) US4011326A (enExample)
JP (1) JPS6037116B2 (enExample)
AU (1) AU505159B2 (enExample)
BE (1) BE844577A (enExample)
CH (1) CH603661A5 (enExample)
DE (1) DE2633905A1 (enExample)
DK (1) DK320276A (enExample)
ES (1) ES450245A1 (enExample)
FR (1) FR2319354A1 (enExample)
GB (1) GB1497985A (enExample)
HU (1) HU172167B (enExample)
NL (1) NL7607794A (enExample)
SE (1) SE431545B (enExample)
ZA (1) ZA764527B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085368Y2 (ja) * 1987-03-05 1996-02-14 日産自動車株式会社 内燃機関のコネクティングロッド
PT937075E (pt) * 1996-11-11 2004-05-31 Altana Pharma Ag Novas imidazo- e oxazolo-piridinas como inibidores da fosfodiesterese
ATE327753T1 (de) 2001-05-15 2006-06-15 Hoffmann La Roche Carbonsäure-substituierte oxazol-derivate zur verwendung als ppar-alpha und -gamma aktivatoren zur behandlung von diabetes
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
RU2295520C2 (ru) * 2002-07-03 2007-03-20 Ф.Хоффманн-Ля Рош Аг ПРОИЗВОДНЫЕ ОКСАЗОЛА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ СЕНСИБИЛИЗАТОРОВ ИНСУЛИНА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ АКТИВИРУЮЩИМ ДЕЙСТВИЕМ В ОТНОШЕНИИ PRARα И/ИЛИ PRARγ
EP1537091B1 (en) * 2002-08-30 2010-10-06 F. Hoffmann-La Roche AG Novel 2-arylthiazole compounds as pparalpha and ppargamma agonists
JP4286782B2 (ja) * 2002-09-12 2009-07-01 エフ.ホフマン−ラ ロシュ アーゲー 糖尿病の治療に有用な、pparアゴニストとしてのn−置換−1h−インドール−5−プロピオン酸化合物
RU2315767C2 (ru) * 2002-11-25 2008-01-27 Ф.Хоффманн-Ля Рош Аг Индолилпроизводные, способ их получения, фармацевтическая композиция, способ лечения и/или профилактики заболеваний
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935195A (en) * 1969-04-28 1976-01-27 Sterling Drug Inc. 4,4'-Stilbenebis-pyridooxazoles and related optical brighteners and polymeric compositions brightened thereby
FR2148362A1 (en) * 1971-08-11 1973-03-23 Ferlux 2-amino-(4,5-b)-oxazolopyridine cpds - with analgesic,anti-inflammato anticonvulsant,muscle relaxant and diuretic activity
AR208500A1 (es) * 1972-06-14 1977-02-15 Merck & Co Inc Procedimiento para la preparacion de derivados de oxazolo(4,5-b)-piridinas

Also Published As

Publication number Publication date
CH603661A5 (enExample) 1978-08-31
US4011326A (en) 1977-03-08
SE7608037L (sv) 1977-01-30
DE2633905A1 (de) 1977-02-17
ES450245A1 (es) 1979-05-16
NL7607794A (nl) 1977-02-01
SE431545B (sv) 1984-02-13
JPS6037116B2 (ja) 1985-08-24
AU505159B2 (en) 1979-11-08
JPS5217495A (en) 1977-02-09
DK320276A (da) 1977-01-30
FR2319354B1 (enExample) 1979-07-20
GB1497985A (en) 1978-01-12
BE844577A (fr) 1977-01-28
AU1605276A (en) 1978-01-26
ZA764527B (en) 1978-03-29
FR2319354A1 (fr) 1977-02-25

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