HU172167B - Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov - Google Patents

Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov

Info

Publication number
HU172167B
HU172167B HU76ME00002006A HUME002006A HU172167B HU 172167 B HU172167 B HU 172167B HU 76ME00002006 A HU76ME00002006 A HU 76ME00002006A HU ME002006 A HUME002006 A HU ME002006A HU 172167 B HU172167 B HU 172167B
Authority
HU
Hungary
Prior art keywords
bracket
oxasolo
pyridines
substituted
producing new
Prior art date
Application number
HU76ME00002006A
Other languages
English (en)
Inventor
Norman P Jensen
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HU172167B publication Critical patent/HU172167B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72Polycyclic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU76ME00002006A 1975-07-29 1976-07-28 Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov HU172167B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/600,169 US4011326A (en) 1975-07-29 1975-07-29 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents

Publications (1)

Publication Number Publication Date
HU172167B true HU172167B (hu) 1978-06-28

Family

ID=24402575

Family Applications (1)

Application Number Title Priority Date Filing Date
HU76ME00002006A HU172167B (hu) 1975-07-29 1976-07-28 Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov

Country Status (14)

Country Link
US (1) US4011326A (hu)
JP (1) JPS6037116B2 (hu)
AU (1) AU505159B2 (hu)
BE (1) BE844577A (hu)
CH (1) CH603661A5 (hu)
DE (1) DE2633905A1 (hu)
DK (1) DK320276A (hu)
ES (1) ES450245A1 (hu)
FR (1) FR2319354A1 (hu)
GB (1) GB1497985A (hu)
HU (1) HU172167B (hu)
NL (1) NL7607794A (hu)
SE (1) SE431545B (hu)
ZA (1) ZA764527B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085368Y2 (ja) * 1987-03-05 1996-02-14 日産自動車株式会社 内燃機関のコネクティングロッド
PT937075E (pt) * 1996-11-11 2004-05-31 Altana Pharma Ag Novas imidazo- e oxazolo-piridinas como inibidores da fosfodiesterese
IL158589A0 (en) 2001-05-15 2004-05-12 Hoffmann La Roche Carboxylic acid substituted oxazole derivatives for use as ppar-alpha and -gamma activators in the treatment of diabetes
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
MXPA04012840A (es) * 2002-07-03 2005-02-24 Hoffmann La Roche Derivados de oxazol y su uso como sensibilizadores a la insulina.
RU2296754C2 (ru) * 2002-08-30 2007-04-10 Ф.Хоффманн-Ля Рош Аг НОВЫЕ СОЕДИНЕНИЯ 2-АРИЛТИАЗОЛА В КАЧЕСТВЕ АГОНИСТОВ PPAR α И PPAR γ
EP1539746B1 (en) * 2002-09-12 2006-11-15 F. Hoffmann-La Roche Ag N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes
EP1567523B1 (en) * 2002-11-25 2008-08-20 F.Hoffmann-La Roche Ag Indolyl derivatives
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935195A (en) * 1969-04-28 1976-01-27 Sterling Drug Inc. 4,4'-Stilbenebis-pyridooxazoles and related optical brighteners and polymeric compositions brightened thereby
FR2148362A1 (en) * 1971-08-11 1973-03-23 Ferlux 2-amino-(4,5-b)-oxazolopyridine cpds - with analgesic,anti-inflammato anticonvulsant,muscle relaxant and diuretic activity
AR208500A1 (es) * 1972-06-14 1977-02-15 Merck & Co Inc Procedimiento para la preparacion de derivados de oxazolo(4,5-b)-piridinas

Also Published As

Publication number Publication date
SE7608037L (sv) 1977-01-30
AU1605276A (en) 1978-01-26
SE431545B (sv) 1984-02-13
JPS5217495A (en) 1977-02-09
FR2319354A1 (fr) 1977-02-25
ZA764527B (en) 1978-03-29
BE844577A (fr) 1977-01-28
US4011326A (en) 1977-03-08
ES450245A1 (es) 1979-05-16
DE2633905A1 (de) 1977-02-17
JPS6037116B2 (ja) 1985-08-24
DK320276A (da) 1977-01-30
NL7607794A (nl) 1977-02-01
GB1497985A (en) 1978-01-12
FR2319354B1 (hu) 1979-07-20
CH603661A5 (hu) 1978-08-31
AU505159B2 (en) 1979-11-08

Similar Documents

Publication Publication Date Title
HU173541B (hu) Sposob poluchenija 21-fenilsul'fonil-pregna-4,17-skobka zakryta-,20-tien-3-onov
HU172697B (hu) Sposob poluchenija proizvodnykh tieno-skobka-2,3-c-skobka zakryta-piridina
HU175504B (hu) Sposob poluchenija novykh pirazinkarboksamidov
HU177817B (en) Process for producing 3,4-dihydroquinasoline derivatives
HU175369B (hu) Sposob poluchneija novykh proizvodnykh 16-degidro-androstana
HU173003B (hu) Sposob poluchenija novykh tiazolo-skobka-3,4-b-skobka zakryta-izokinolinov
HU172167B (hu) Sposob poluchenija novykh 2-zamehhennykh oksazolo-skobka-4,5-b-skobka zakryta-piridinov
HU175175B (hu) Sposob poluchenija novykh proizvodnykh butirofenona
HU170888B (hu) Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov
HU179070B (en) Process for producing new 3-acyloxymethyl-cepheme compounds
HU175422B (hu) Sposob poluchenija novykh proizvodnykh 11-okso-prostaglandinov
HU172460B (hu) Sposob poluchenija novykh proizvodnykh 5,6-digidro-3h-pirimidin-4-ona
HU175728B (hu) Sposob poluchenija 13,14-degidro-11-dezoksi-prostagland
HU178507B (en) Process for producing n,n-comma above-bis-trimethyl-silil-urea
HU173708B (hu) Sposob poluchenija geterokolloidnogo 18-arabinozil-2-n-butil-3,7,11,15,19,21,23,27,25,37-dekagidroksi-4,16,32,34,36-pentametil-tetrakona-16,32-dien-35-0-lakton-40-guanidiniumsul'fata
HU173129B (hu) Sposob poluchenija novykh proizvodnykh zamehhennykh penam- i cefem-soedinenijj soderzhahhikh piperazino-gruppy
HU177770B (en) Process for producing 2,2-difluoro-prostaglandine derivatives
HU171663B (hu) Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
HU172729B (hu) Sposob poluchenija novykh cefem-soedinenijj
HU172063B (hu) Sposob poluchenija priozvodnykh n-skobka-5-tetrazolil-skobka zakryta-1-okso-6-alkoksi-1h-pirimido-skobka-1,2-a-skobka zakryta-kinolin-2-karboksamidov
HU172055B (hu) Sposob poluchenija proizvodnykh tieno-skobka-3,2-c-skobka zakryta-piridina
YU179376A (en) Process for obtaining 2-chloro-n-isopropyl-2,3-dimethylacetanilide
HU171738B (hu) Sposob poluchenija proizvodnykh kinoksalin-1,4-dioksid-azometina
HU174020B (hu) Sposob poluchenija proizvodnykh 1,4-benzodiazepina, zamehhennykh v pozicii 2
HU174832B (hu) Sposob poluchenija n,n-diehtil-2-/al'fa-naftoksi/-propionamida