HU172047B - Sposob aroilirovanija proizvodnykh 1-alkil-pirrol-2-il-uksusnoj kisloty bez katalizatora - Google Patents
Sposob aroilirovanija proizvodnykh 1-alkil-pirrol-2-il-uksusnoj kisloty bez katalizatoraInfo
- Publication number
- HU172047B HU172047B HU76ME00001986A HUME001986A HU172047B HU 172047 B HU172047 B HU 172047B HU 76ME00001986 A HU76ME00001986 A HU 76ME00001986A HU ME001986 A HUME001986 A HU ME001986A HU 172047 B HU172047 B HU 172047B
- Authority
- HU
- Hungary
- Prior art keywords
- aroylation
- pyrrol
- catalyst
- alkyl
- acetic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/583,065 US3998844A (en) | 1975-06-02 | 1975-06-02 | Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU172047B true HU172047B (hu) | 1978-05-28 |
Family
ID=24331553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU76ME00001986A HU172047B (hu) | 1975-06-02 | 1976-06-02 | Sposob aroilirovanija proizvodnykh 1-alkil-pirrol-2-il-uksusnoj kisloty bez katalizatora |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US3998844A (hu) |
| JP (1) | JPS5919536B2 (hu) |
| AT (1) | AT358572B (hu) |
| AU (1) | AU497557B2 (hu) |
| BE (1) | BE842458A (hu) |
| CA (1) | CA1066297A (hu) |
| CH (1) | CH603578A5 (hu) |
| CS (1) | CS220310B2 (hu) |
| DE (2) | DE2624558A1 (hu) |
| DK (1) | DK154976C (hu) |
| ES (1) | ES448408A1 (hu) |
| FR (1) | FR2313364A1 (hu) |
| GB (1) | GB1477998A (hu) |
| HU (1) | HU172047B (hu) |
| IL (1) | IL49687A (hu) |
| IN (1) | IN141746B (hu) |
| NL (1) | NL7605958A (hu) |
| NZ (1) | NZ180785A (hu) |
| PL (1) | PL101700B1 (hu) |
| PT (1) | PT65161B (hu) |
| RO (1) | RO69252A (hu) |
| SE (1) | SE414765B (hu) |
| YU (1) | YU40648B (hu) |
| ZA (1) | ZA763191B (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048191A (en) * | 1975-06-27 | 1977-09-13 | Mcneil Laboratories, Incorporated | Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds |
| US4207237A (en) * | 1977-04-20 | 1980-06-10 | Mcneilab, Inc. | Preparation of pyrrole-2-acetates |
| US4200645A (en) * | 1977-05-10 | 1980-04-29 | Beecham Group Limited | Pyrrole derivatives |
| US4119639A (en) * | 1977-06-27 | 1978-10-10 | Mcneil Laboratories, Incorporated | Preparation of 5-aroylpyrrole-2-acetic acid derivatives |
| GB1592996A (en) * | 1977-10-10 | 1981-07-15 | Rolland Sa A | Acylated pyrrole carboxylic acids and derivatives thereof |
| SE435278B (sv) * | 1977-12-08 | 1984-09-17 | Sagami Chem Res | 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat |
| JPS5481264A (en) * | 1977-12-08 | 1979-06-28 | Sagami Chem Res Center | Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid |
| US4216150A (en) * | 1978-10-16 | 1980-08-05 | Mcneil Lab, Inc. | Preparation of pyrrole-2-acetates |
| US4213905A (en) * | 1979-06-25 | 1980-07-22 | Mcneilab, Inc. | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts |
| US4284562A (en) * | 1979-11-27 | 1981-08-18 | Mcneilab, Inc. | Process for preparing pyrrole-2-acetic acids |
| US4255335A (en) * | 1980-04-03 | 1981-03-10 | Mcneilab, Inc. | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid derivatives |
| US4299770A (en) * | 1980-05-29 | 1981-11-10 | Mallinckrodt, Inc. | Recovery of substituted pyrrole acetate |
| NZ201468A (en) * | 1981-08-10 | 1986-02-21 | Merck & Co Inc | 5-aroyl-4-pyrrolyl-alkanoic acid derivatives and pharmaceutical compositions |
| US5418236A (en) * | 1993-12-23 | 1995-05-23 | Ortho Pharmaceutical Corporation | Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles |
| WO2001028997A2 (en) | 1999-10-21 | 2001-04-26 | Emory University | Synthesis of 4-substituted pyrrole-2-carbaldehyde compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
| US3846447A (en) * | 1972-08-03 | 1974-11-05 | Mcneilab Inc | Preparation of 5-aroyl-pyrroles and intermediates therefor |
-
1975
- 1975-06-02 US US05/583,065 patent/US3998844A/en not_active Expired - Lifetime
-
1976
- 1976-05-05 IN IN783/CAL/76A patent/IN141746B/en unknown
- 1976-05-05 NZ NZ180785A patent/NZ180785A/xx unknown
- 1976-05-10 GB GB1907276A patent/GB1477998A/en not_active Expired
- 1976-05-14 FR FR7614686A patent/FR2313364A1/fr active Granted
- 1976-05-28 AU AU14405/76A patent/AU497557B2/en not_active Expired
- 1976-05-31 IL IL49687A patent/IL49687A/xx unknown
- 1976-05-31 PT PT65161A patent/PT65161B/pt unknown
- 1976-05-31 JP JP51062478A patent/JPS5919536B2/ja not_active Expired
- 1976-05-31 RO RO7686309A patent/RO69252A/ro unknown
- 1976-05-31 CA CA253,677A patent/CA1066297A/en not_active Expired
- 1976-05-31 ES ES448408A patent/ES448408A1/es not_active Expired
- 1976-06-01 ZA ZA00763191A patent/ZA763191B/xx unknown
- 1976-06-01 CH CH689476A patent/CH603578A5/xx not_active IP Right Cessation
- 1976-06-01 DE DE19762624558 patent/DE2624558A1/de not_active Withdrawn
- 1976-06-01 AT AT401476A patent/AT358572B/de not_active IP Right Cessation
- 1976-06-01 BE BE167534A patent/BE842458A/xx not_active IP Right Cessation
- 1976-06-01 SE SE7606165A patent/SE414765B/xx unknown
- 1976-06-01 DE DE2624557A patent/DE2624557C2/de not_active Expired
- 1976-06-02 YU YU1360/76A patent/YU40648B/xx unknown
- 1976-06-02 NL NL7605958A patent/NL7605958A/xx not_active Application Discontinuation
- 1976-06-02 PL PL1976190059A patent/PL101700B1/pl unknown
- 1976-06-02 HU HU76ME00001986A patent/HU172047B/hu unknown
- 1976-06-02 CS CS763662A patent/CS220310B2/cs unknown
- 1976-06-02 DK DK243676A patent/DK154976C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| PT65161B (en) | 1978-07-03 |
| US3998844A (en) | 1976-12-27 |
| AT358572B (de) | 1980-09-25 |
| SE7606165L (sv) | 1976-12-03 |
| PL101700B1 (pl) | 1979-01-31 |
| DK154976B (da) | 1989-01-16 |
| FR2313364B1 (hu) | 1980-09-12 |
| DE2624557C2 (de) | 1984-04-05 |
| CA1066297A (en) | 1979-11-13 |
| AU497557B2 (en) | 1978-12-14 |
| YU136076A (en) | 1982-05-31 |
| AU1440576A (en) | 1977-12-01 |
| ES448408A1 (es) | 1977-11-16 |
| DK154976C (da) | 1989-06-05 |
| DE2624558A1 (de) | 1976-12-23 |
| YU40648B (en) | 1986-04-30 |
| BE842458A (fr) | 1976-12-01 |
| NZ180785A (en) | 1978-03-06 |
| DE2624557A1 (de) | 1976-12-23 |
| RO69252A (ro) | 1981-08-30 |
| PT65161A (en) | 1976-06-01 |
| DK243676A (da) | 1976-12-03 |
| ATA401476A (de) | 1980-02-15 |
| JPS51143664A (en) | 1976-12-10 |
| CS220310B2 (en) | 1983-03-25 |
| JPS5919536B2 (ja) | 1984-05-07 |
| CH603578A5 (hu) | 1978-08-31 |
| SE414765B (sv) | 1980-08-18 |
| IL49687A (en) | 1978-10-31 |
| NL7605958A (nl) | 1976-12-06 |
| IL49687A0 (en) | 1976-07-30 |
| IN141746B (hu) | 1977-04-09 |
| FR2313364A1 (fr) | 1976-12-31 |
| ZA763191B (en) | 1978-01-25 |
| GB1477998A (en) | 1977-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 |