HRP970630B1 - Hepapeptide oxytocin analogues - Google Patents
Hepapeptide oxytocin analoguesInfo
- Publication number
- HRP970630B1 HRP970630B1 HR970630A HRP970630A HRP970630B1 HR P970630 B1 HRP970630 B1 HR P970630B1 HR 970630 A HR970630 A HR 970630A HR P970630 A HRP970630 A HR P970630A HR P970630 B1 HRP970630 B1 HR P970630B1
- Authority
- HR
- Croatia
- Prior art keywords
- hepapeptide
- oxytocin analogues
- oxytocin
- analogues
- hepapeptide oxytocin
- Prior art date
Links
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pregnancy & Childbirth (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9604341A SE9604341D0 (sv) | 1996-11-26 | 1996-11-26 | Hepta-peptide oxytocin analogue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP970630A2 HRP970630A2 (en) | 1998-10-31 |
| HRP970630B1 true HRP970630B1 (en) | 2002-04-30 |
Family
ID=20404757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR970630A HRP970630B1 (en) | 1996-11-26 | 1997-11-21 | Hepapeptide oxytocin analogues |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6143722A (da) |
| EP (1) | EP0938496B1 (da) |
| JP (1) | JP3405460B2 (da) |
| KR (1) | KR100463132B1 (da) |
| CN (1) | CN1129606C (da) |
| AR (1) | AR008531A1 (da) |
| AT (1) | ATE242264T1 (da) |
| AU (1) | AU713424B2 (da) |
| BR (1) | BR9713366B1 (da) |
| CA (1) | CA2272990C (da) |
| CZ (1) | CZ299532B6 (da) |
| DE (1) | DE69722651T2 (da) |
| DK (1) | DK0938496T3 (da) |
| EE (1) | EE03832B1 (da) |
| ES (1) | ES2203823T3 (da) |
| HR (1) | HRP970630B1 (da) |
| HU (1) | HU228568B1 (da) |
| IL (1) | IL129519A (da) |
| LT (1) | LT4650B (da) |
| LV (1) | LV12350B (da) |
| MY (1) | MY125555A (da) |
| NO (1) | NO321380B1 (da) |
| NZ (1) | NZ336445A (da) |
| PL (1) | PL189292B1 (da) |
| PT (1) | PT938496E (da) |
| RO (1) | RO120772B1 (da) |
| RU (1) | RU2180668C2 (da) |
| SE (1) | SE9604341D0 (da) |
| SI (1) | SI20026B (da) |
| SK (1) | SK283800B6 (da) |
| TR (1) | TR199901028T2 (da) |
| UA (1) | UA54459C2 (da) |
| WO (1) | WO1998023636A1 (da) |
| ZA (1) | ZA9710518B (da) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2181297C2 (ru) | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
| US6476072B1 (en) * | 2000-11-21 | 2002-11-05 | Arthur Vanmoor | Method of treating menstrual pain by enhancing the effectiveness of the human immune system |
| WO2003072597A1 (en) * | 2002-02-27 | 2003-09-04 | Ferring Bv | Intermediates and methods for making heptapeptide oxytocin analogues |
| EP1504268A2 (en) * | 2002-05-02 | 2005-02-09 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with oxytocin receptor (oxtr) |
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| UA76639C2 (uk) * | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Гомеопатичний лікарський засіб та спосіб лікування еректильних дисфункцій |
| ATE301990T1 (de) * | 2003-07-25 | 2005-09-15 | Ferring Bv | Pharmazeutische desmopressin-zubereitung als feste darreichungsform und methode zu ihrer herstellung |
| EP1530967B1 (en) * | 2003-11-13 | 2006-05-03 | Ferring B.V. | Blister pack and solid dosage form comprising desmopressin |
| EP1555029A1 (en) | 2004-01-19 | 2005-07-20 | Ferring B.V. | Use of substances having oxytocin antagonistic properties for the preparation of a medicament for treating hypertension |
| US20060171909A1 (en) * | 2005-02-03 | 2006-08-03 | The Procter & Gamble Company | Cosmetic compositions comprising colorants with low free dye |
| SE528446C2 (sv) * | 2006-03-02 | 2006-11-14 | Ferring Int Ct Sa | Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse |
| AU2008283929B2 (en) | 2007-08-06 | 2013-10-10 | Serenity Pharmaceuticals, Llc | Methods and devices for desmopressin drug delivery |
| DK2260053T3 (da) * | 2008-03-31 | 2014-06-23 | Ferring Bv | Oxytocin-analoger |
| PL2712622T3 (pl) | 2008-05-21 | 2017-01-31 | Ferring B.V. | Ulegająca rozpadowi w ustach desmopresyna do zwiększania początkowego okresu snu niezakłócanego przez nokturię |
| US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
| US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
| TWI463990B (zh) * | 2009-09-21 | 2014-12-11 | Ferring Bv | 催產素受體促進劑 |
| PH12013500107A1 (en) | 2010-07-15 | 2013-03-11 | Oleg Iliich Epshtein | A method of increasing the effect of an activated-potentiated form of an antibody |
| JO3400B1 (ar) * | 2010-09-30 | 2019-10-20 | Ferring Bv | مركب صيدلاني من كاربيتوسين |
| JP6150726B2 (ja) | 2011-03-09 | 2017-06-21 | Jitsubo株式会社 | 新規な非ペプチド性架橋構造を含む架橋ペプチド、ならびに該架橋ペプチドの合成方法および該方法に用いる新規な有機化合物 |
| CN102875650B (zh) * | 2012-09-26 | 2014-06-11 | 深圳翰宇药业股份有限公司 | 巴卢西班的制备方法 |
| US9365615B2 (en) | 2013-09-09 | 2016-06-14 | Jitsubo Co., Ltd. | Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method |
| EP3037101B1 (en) | 2014-12-22 | 2019-03-06 | Ferring B.V. | Oxytocin receptor antagonist therapy in the luteal phase for implantation and pregnancy in women undergoing assisted reproductive technologies |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| CA3001057A1 (en) | 2015-10-06 | 2017-04-13 | Ferring B.V. | New methods for making barusiban and its intermediates |
| CA3009576A1 (en) | 2016-01-04 | 2017-07-13 | Merck Serono S.A. | L-valinate of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof |
| UA127283C2 (uk) | 2016-07-21 | 2023-07-12 | Обсева С.А. | Спосіб застосування антагоніста окситоцину для сприяння імплантації ембріона і запобігання викидню |
| US20220323410A1 (en) | 2019-09-03 | 2022-10-13 | ObsEva S.A. | Oxytocin antagonist dosing regimens for promoting embryo implantation and preventing miscarriage |
| WO2021160597A1 (en) | 2020-02-10 | 2021-08-19 | ObsEva S.A. | Biomarkers for oxytocin receptor antagonist therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL155712B1 (en) * | 1987-12-21 | 1991-12-31 | Sandoz Ag | Method of obtaining novel crystalline form of cyclosporin |
| US5373089A (en) * | 1988-09-02 | 1994-12-13 | Northwestern University | Oxytocin antagonist |
| CA2036973A1 (en) * | 1990-02-27 | 1991-08-28 | Mark G. Bock | Cyclic hexapeptide oxytocin antagonists |
| SE9002384D0 (sv) * | 1990-07-09 | 1990-07-09 | Ferring Ab | Derivat av baklobshormoner |
| DE4022247A1 (de) * | 1990-07-12 | 1992-01-16 | Hoechst Ag | Verfahren zur extraktiven abtrennung von 2-alkylthio-5-phenylpyrimidinen aus ihren reaktionsgemischen |
| SE501678C2 (sv) * | 1993-07-13 | 1995-04-10 | Ferring Bv | Peptid med oxytocinantagonistaktivitet samt farmaceutisk komposition innehållande nämnda peptid |
| SE523819C2 (sv) | 1994-01-27 | 2004-05-18 | Per-Ingvar Nilsson | Accelerationsmunstycke samt metod för dess användning |
| SE9400918L (sv) | 1994-03-18 | 1995-09-19 | Anne Fjellstad Paulsen | Stabiliserad komposition för oral administrering av peptider |
| SE503085C2 (sv) | 1995-01-25 | 1996-03-25 | Valeo Engine Cooling Ab | Värmeväxlartank med ändstycken, förfarande för framställning av en sådan tank, samt värmeväxlare försedd med en sådan |
-
1996
- 1996-11-26 SE SE9604341A patent/SE9604341D0/xx unknown
-
1997
- 1997-11-21 BR BRPI9713366-3A patent/BR9713366B1/pt not_active IP Right Cessation
- 1997-11-21 NZ NZ336445A patent/NZ336445A/en not_active IP Right Cessation
- 1997-11-21 UA UA99042410A patent/UA54459C2/uk unknown
- 1997-11-21 PT PT97946210T patent/PT938496E/pt unknown
- 1997-11-21 RU RU99113364/04A patent/RU2180668C2/ru active
- 1997-11-21 CN CN97180014A patent/CN1129606C/zh not_active Expired - Fee Related
- 1997-11-21 TR TR1999/01028T patent/TR199901028T2/xx unknown
- 1997-11-21 WO PCT/SE1997/001968 patent/WO1998023636A1/en not_active Ceased
- 1997-11-21 DE DE69722651T patent/DE69722651T2/de not_active Expired - Lifetime
- 1997-11-21 ZA ZA9710518A patent/ZA9710518B/xx unknown
- 1997-11-21 EP EP97946210A patent/EP0938496B1/en not_active Expired - Lifetime
- 1997-11-21 PL PL97333876A patent/PL189292B1/pl unknown
- 1997-11-21 US US09/308,912 patent/US6143722A/en not_active Expired - Lifetime
- 1997-11-21 KR KR10-1999-7004449A patent/KR100463132B1/ko not_active Expired - Lifetime
- 1997-11-21 SI SI9720076A patent/SI20026B/sl unknown
- 1997-11-21 JP JP52460298A patent/JP3405460B2/ja not_active Expired - Lifetime
- 1997-11-21 CZ CZ0183299A patent/CZ299532B6/cs not_active IP Right Cessation
- 1997-11-21 HU HU0000577A patent/HU228568B1/hu unknown
- 1997-11-21 DK DK97946210T patent/DK0938496T3/da active
- 1997-11-21 SK SK704-99A patent/SK283800B6/sk not_active IP Right Cessation
- 1997-11-21 ES ES97946210T patent/ES2203823T3/es not_active Expired - Lifetime
- 1997-11-21 EE EEP199900210A patent/EE03832B1/xx unknown
- 1997-11-21 AT AT97946210T patent/ATE242264T1/de active
- 1997-11-21 HR HR970630A patent/HRP970630B1/xx not_active IP Right Cessation
- 1997-11-21 IL IL12951997A patent/IL129519A/en not_active IP Right Cessation
- 1997-11-21 RO RO99-00593A patent/RO120772B1/ro unknown
- 1997-11-21 AU AU51429/98A patent/AU713424B2/en not_active Expired
- 1997-11-21 CA CA002272990A patent/CA2272990C/en not_active Expired - Lifetime
- 1997-11-25 MY MYPI97005691A patent/MY125555A/en unknown
- 1997-11-26 AR ARP970105543A patent/AR008531A1/es active IP Right Grant
-
1999
- 1999-04-30 LV LVP-99-77A patent/LV12350B/en unknown
- 1999-05-11 LT LT99-052A patent/LT4650B/lt not_active IP Right Cessation
- 1999-05-26 NO NO19992532A patent/NO321380B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20160928 Year of fee payment: 20 |
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| PB20 | Patent expired after termination of 20 years |
Effective date: 20171121 |