HRP950485A2 - Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence - Google Patents
Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence Download PDFInfo
- Publication number
- HRP950485A2 HRP950485A2 HR08/308,859A HRP950485A HRP950485A2 HR P950485 A2 HRP950485 A2 HR P950485A2 HR P950485 A HRP950485 A HR P950485A HR P950485 A2 HRP950485 A2 HR P950485A2
- Authority
- HR
- Croatia
- Prior art keywords
- serotonin reuptake
- selective serotonin
- reuptake inhibitor
- naltrexone
- fluoxetine
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30885994A | 1994-09-19 | 1994-09-19 |
Publications (1)
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HRP950485A2 true HRP950485A2 (en) | 1997-08-31 |
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Application Number | Title | Priority Date | Filing Date |
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HR08/308,859A HRP950485A2 (en) | 1994-09-19 | 1995-09-19 | Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence |
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US (1) | US5958962A (es) |
EP (1) | EP0782445B1 (es) |
AT (1) | ATE214276T1 (es) |
AU (1) | AU3419995A (es) |
CA (1) | CA2197554A1 (es) |
CO (1) | CO4410317A1 (es) |
DE (1) | DE69525847T2 (es) |
DK (1) | DK0782445T3 (es) |
HR (1) | HRP950485A2 (es) |
WO (1) | WO1996009047A1 (es) |
ZA (1) | ZA957891B (es) |
Families Citing this family (35)
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US6001848A (en) * | 1996-03-25 | 1999-12-14 | The Regents Of The University Of California | Bromocriptine for the treatment of alcoholics diagnosed with the D2 dopamine receptor DRD2 A1 allele |
ATE256457T1 (de) * | 1997-07-01 | 2004-01-15 | Pfizer Prod Inc | In gelatine eingekapselte sertarline dosierungsformen |
BR9810403A (pt) | 1997-07-01 | 2000-08-29 | Pfizer | Sais da sertralina e formas de dosagem de liberação sustentada da sertralina |
AU1018801A (en) * | 1999-10-29 | 2001-05-14 | Novo Nordisk A/S | Use of 3,4-substituted piperidines |
DK2283842T3 (en) * | 2000-02-08 | 2015-05-26 | Euro Celtique Sa | Oral opioid agonist formulations secured against forgery |
US7034036B2 (en) * | 2000-10-30 | 2006-04-25 | Pain Therapeutics, Inc. | Inhibitors of ABC drug transporters at the blood-brain barrier |
EP1262196A3 (en) * | 2001-05-23 | 2002-12-18 | Pfizer Products Inc. | Combination of a monoamine reuptake inhibitor and an opioid antagonist for use in alcoholism and alcohol dependence |
US7034059B2 (en) | 2001-07-02 | 2006-04-25 | Sepracor Inc. | Methods of using norfluoxetine |
HUP0401022A3 (en) * | 2001-08-14 | 2006-11-28 | Biotie Therapies Corp | Method for the preparation of pharmaceutical compositions containing opioid antagonist for treating alcoholism or alcohol abuse |
US20140271788A1 (en) | 2013-03-15 | 2014-09-18 | Monosol Rx, Llc | Sublingual and buccal film compositions |
CN1320886C (zh) | 2002-05-17 | 2007-06-13 | 杜克大学 | 安非他酮与抗惊厥药在制备治疗肥胖症的药物的用途 |
US20050215552A1 (en) * | 2002-05-17 | 2005-09-29 | Gadde Kishore M | Method for treating obesity |
DE10237057A1 (de) * | 2002-08-09 | 2004-03-25 | Grünenthal GmbH | Opioid-Rezeptor-Antagonisten in Pflasterformulierungen |
EP1870096A3 (en) * | 2003-04-29 | 2011-04-20 | Orexigen Therapeutics, Inc. | Compositions for affecting weight loss |
DK2316456T3 (en) | 2003-04-29 | 2017-09-11 | Orexigen Therapeutics Inc | Compositions for affecting weight loss comprising an opioid antagonist and bupropion |
JP2007526438A (ja) * | 2003-06-06 | 2007-09-13 | コンビナトルックス インコーポレイテッド | 組成物の組み合わせの多次元評価システムおよび方法 |
US7713959B2 (en) * | 2004-01-13 | 2010-05-11 | Duke University | Compositions of an anticonvulsant and mirtazapine to prevent weight gain |
US20060160750A1 (en) * | 2004-01-13 | 2006-07-20 | Krishnan K R R | Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for affecting weight loss |
EP1734955A2 (en) | 2004-01-13 | 2006-12-27 | Duke University | Compositions of an anticonvulsant and an antipsychotic drug for affecting weigt loss |
US20060100205A1 (en) * | 2004-04-21 | 2006-05-11 | Eckard Weber | Compositions for affecting weight loss |
EP3132792B1 (en) | 2005-11-22 | 2019-09-11 | Nalpropion Pharmaceuticals, Inc. | Composition and methods for increasing insulin sensitivity |
WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
EP1954316A1 (en) * | 2005-11-28 | 2008-08-13 | Orexigen Therapeutics, Inc. | Methods of treating anxiety disorders |
US20070212307A1 (en) * | 2006-02-10 | 2007-09-13 | Daniel Wermeling | Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same |
US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
KR20170077291A (ko) | 2006-11-09 | 2017-07-05 | 오렉시젠 세러퓨틱스 인크. | 단위 용량 팩키지 |
KR101654176B1 (ko) | 2006-11-09 | 2016-09-09 | 오렉시젠 세러퓨틱스 인크. | 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형 |
US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
JP2011521973A (ja) | 2008-05-30 | 2011-07-28 | オレキシジェン・セラピューティクス・インコーポレーテッド | 内臓脂肪の状態を処置するための方法 |
US20100168119A1 (en) | 2008-11-05 | 2010-07-01 | Pharmorx, Inc. | Compositions and methods for minimizing or reducing agonist-induced desensitization |
AU2011203867B2 (en) | 2010-01-11 | 2015-12-03 | Nalpropion Pharmaceuticals Llc | Methods of providing weight loss therapy in patients with major depression |
ES2802048T3 (es) | 2012-06-06 | 2021-01-15 | Nalpropion Pharmaceuticals Llc | Composición para uso en un método para el tratamiento de sobrepeso y obesidad en pacientes con alto riesgo cardiovascular |
JP6406713B2 (ja) | 2013-01-30 | 2018-10-17 | ファーモレックス セラピューティクス, インコーポレイテッド | 低用量薬剤によるうつ病および他の疾患の処置 |
US8969371B1 (en) | 2013-12-06 | 2015-03-03 | Orexigen Therapeutics, Inc. | Compositions and methods for weight loss in at risk patient populations |
EP3082816B1 (en) | 2013-12-20 | 2019-03-20 | Indivior UK Limited | Intranasal naloxone compositions and methods of making and using same |
Family Cites Families (4)
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US4777173A (en) * | 1987-03-25 | 1988-10-11 | Bristol-Myers Company | Method for treatment of alcohol abuse |
WO1992019241A1 (en) * | 1991-05-07 | 1992-11-12 | Dynagen, Inc. | A controlled, sustained release delivery system for smoking cessation |
US5366990A (en) * | 1991-11-14 | 1994-11-22 | Reid Larry D | Method for treating alcohol abuse and alcoholism |
US5512593A (en) * | 1993-03-02 | 1996-04-30 | John S. Nagle | Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor |
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- 1995-09-07 CA CA002197554A patent/CA2197554A1/en not_active Abandoned
- 1995-09-07 DE DE69525847T patent/DE69525847T2/de not_active Expired - Fee Related
- 1995-09-07 AT AT95931014T patent/ATE214276T1/de not_active IP Right Cessation
- 1995-09-07 DK DK95931014T patent/DK0782445T3/da active
- 1995-09-07 WO PCT/US1995/010987 patent/WO1996009047A1/en active IP Right Grant
- 1995-09-07 AU AU34199/95A patent/AU3419995A/en not_active Abandoned
- 1995-09-07 EP EP95931014A patent/EP0782445B1/en not_active Expired - Lifetime
- 1995-09-19 HR HR08/308,859A patent/HRP950485A2/hr not_active Application Discontinuation
- 1995-09-19 CO CO95043013A patent/CO4410317A1/es unknown
- 1995-09-19 ZA ZA957891A patent/ZA957891B/xx unknown
- 1995-10-13 US US08/542,747 patent/US5958962A/en not_active Expired - Fee Related
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EP0782445B1 (en) | 2002-03-13 |
DK0782445T3 (da) | 2002-05-06 |
ATE214276T1 (de) | 2002-03-15 |
AU3419995A (en) | 1996-04-09 |
CO4410317A1 (es) | 1997-01-09 |
CA2197554A1 (en) | 1996-03-28 |
DE69525847T2 (de) | 2002-09-05 |
US5958962A (en) | 1999-09-28 |
EP0782445A1 (en) | 1997-07-09 |
WO1996009047A1 (en) | 1996-03-28 |
DE69525847D1 (de) | 2002-04-18 |
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