HRP930014A2 - 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates - Google Patents

9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates

Info

Publication number
HRP930014A2
HRP930014A2 HR930014A HRP930014A HRP930014A2 HR P930014 A2 HRP930014 A2 HR P930014A2 HR 930014 A HR930014 A HR 930014A HR P930014 A HRP930014 A HR P930014A HR P930014 A2 HRP930014 A2 HR P930014A2
Authority
HR
Croatia
Prior art keywords
deoxo
aza
deoxy
co2ch2c6h5
homoeritromycin
Prior art date
Application number
HR930014A
Other languages
English (en)
Inventor
Gabrijela Kobrehel
Gorjana Lazarevski
Slobodan Oki
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Priority to HR930014A priority Critical patent/HRP930014A2/xx
Priority to DE69400125T priority patent/DE69400125T2/de
Priority to AT94100032T priority patent/ATE136550T1/de
Priority to EP94100032A priority patent/EP0606062B1/en
Priority to ES94100032T priority patent/ES2089863T3/es
Priority to JP06000613A priority patent/JP3056035B2/ja
Priority to US08/178,559 priority patent/US5434140A/en
Publication of HRP930014A2 publication Critical patent/HRP930014A2/xx
Publication of HRP930014B1 publication Critical patent/HRP930014B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HR930014A 1993-01-08 1993-01-08 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates HRP930014A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
HR930014A HRP930014A2 (en) 1993-01-08 1993-01-08 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
DE69400125T DE69400125T2 (de) 1993-01-08 1994-01-03 9-Deoxo-9a-aza-11-deoxy-9a-homoerythromycin A 9a, 11-zyklische Carbamate
AT94100032T ATE136550T1 (de) 1993-01-08 1994-01-03 9-deoxo-9a-aza-11-deoxy-9a-homoerythromycin a 9a, 11-zyklische carbamate
EP94100032A EP0606062B1 (en) 1993-01-08 1994-01-03 9-Deoxo-9a-aza-11-deoxy-9a-homoerythromycin A 9a,11-cyclic carbamates
ES94100032T ES2089863T3 (es) 1993-01-08 1994-01-03 9a,11-carbamatos ciclicos de 9-desoxo-9a-aza-11-desoxi-9a-homoeritromicina a.
JP06000613A JP3056035B2 (ja) 1993-01-08 1994-01-07 ９−デオキソ−９ａ−アザ−１１−デオキシ−９ａ−ホモエリスロマイシンＡ ９ａ，１１−環式カルバメート
US08/178,559 US5434140A (en) 1993-01-08 1994-01-07 9-deoxo-9a-aza-11-deoxy-9a-homoerythromycin a 9a,11-cyclic carbamates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR930014A HRP930014A2 (en) 1993-01-08 1993-01-08 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates

Publications (2)

Publication Number Publication Date
HRP930014A2 true HRP930014A2 (en) 1994-08-31
HRP930014B1 HRP930014B1 (es) 1998-12-31

Family

ID=10945869

Family Applications (1)

Application Number Title Priority Date Filing Date
HR930014A HRP930014A2 (en) 1993-01-08 1993-01-08 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates

Country Status (7)

Country Link
US (1) US5434140A (es)
EP (1) EP0606062B1 (es)
JP (1) JP3056035B2 (es)
AT (1) ATE136550T1 (es)
DE (1) DE69400125T2 (es)
ES (1) ES2089863T3 (es)
HR (1) HRP930014A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP2007204490A (ja) * 1995-08-03 2007-08-16 Chugai Pharmaceut Co Ltd エリスロマイシン誘導体の製造方法
US5780605A (en) * 1997-09-08 1998-07-14 Abbott Laboratories 6,9-bridged erythromycin derivatives
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
US6787342B2 (en) * 2000-02-16 2004-09-07 Merial Limited Paste formulations
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
US7271155B2 (en) * 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
CN102993250B (zh) * 2011-07-06 2016-02-10 洛阳惠中兽药有限公司 C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331893A (en) * 1976-09-24 1982-05-25 Giddings & Lewis, Inc. Boolean logic processor without accumulator output feedback
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
US4492688A (en) * 1983-11-25 1985-01-08 Pfizer Inc. Antibacterial cyclic ethers of 9-deoxo-9a-aza-9a-homoerythromycin A and intermediates therefor
EP0132026B1 (en) * 1983-05-23 1986-12-30 Pfizer Inc. Antibacterial cyclic ethers of 9-deoxo-9a-aza-9a-homoerythromycin a and intermediates therefor
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
EP0559896B1 (en) * 1990-11-28 1997-08-27 Taisho Pharmaceutical Co. Ltd 6-o-methylerythromycin a derivative

Also Published As

Publication number Publication date
JP3056035B2 (ja) 2000-06-26
DE69400125D1 (de) 1996-05-15
HRP930014B1 (es) 1998-12-31
ATE136550T1 (de) 1996-04-15
EP0606062A1 (en) 1994-07-13
DE69400125T2 (de) 1996-11-28
EP0606062B1 (en) 1996-04-10
ES2089863T3 (es) 1996-10-01
JPH0789980A (ja) 1995-04-04
US5434140A (en) 1995-07-18

Similar Documents

Publication Publication Date Title
CA2293397A1 (en) C-4''-substituted macrolide derivatives
HRP930014B1 (es)
CA2349338A1 (en) Novel macrolide antibiotics
CA2137395A1 (en) 9a-N-(N'-Carbamoyl) and 9a-N-(N' - Thiocarbamoyl) Derivatives of 9-Deoxo-9a-AZA-9a-Homoerythromycin A
CA2286511A1 (en) Novel macrolide derivatives
FI102547B1 (fi) Menetelmä valmistaa farmakologisesti käyttökelpoista peptidiyhdistettä
WO2002068438A3 (en) 9a-n-[n'-(phenylsulfonyl)carbamoyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin a and of 5-0-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerythronolide a
KR910000775A (ko) 무라밀 디펩티드 유도체
PL322862A1 (en) Novel compounds 9-n-ethenylic derivtives of 9(s)-erythromycilamine
HRP970714B1 (en) Beta,beta-disubstituted derivatives of 9-deoxo-9a-n-ethenyl-9a-aza-9a-homoerythromycin a
CA2056823A1 (en) Derivatives of 10,11,12,13-Tetrahydrodesmycosin Processes for Preparation, and Use Thereof in Pharmaceuticals
MXPA99003849A (es) Derivados 9a, 11b-deshidro de 9-oxima-3-ceto-6-0-metileritromicina.

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
PNAN Change of the applicant name, address/residence

Owner name: GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O.,

PPPP Transfer of rights

Owner name: PLIVA-ISTRAZIVACKI INSTITUT D.O.O., HR

ODRP Renewal fee for the maintenance of a patent

Payment date: 20080107

Year of fee payment: 16

PBON Lapse due to non-payment of renewal fee

Effective date: 20090109