HRP20211260T1 - Profilaksa i liječenje neisseria gonorrhoeae očne infekcije - Google Patents
Profilaksa i liječenje neisseria gonorrhoeae očne infekcije Download PDFInfo
- Publication number
- HRP20211260T1 HRP20211260T1 HRP20211260TT HRP20211260T HRP20211260T1 HR P20211260 T1 HRP20211260 T1 HR P20211260T1 HR P20211260T T HRP20211260T T HR P20211260TT HR P20211260 T HRP20211260 T HR P20211260T HR P20211260 T1 HRP20211260 T1 HR P20211260T1
- Authority
- HR
- Croatia
- Prior art keywords
- compound
- use according
- eye infection
- prophylaxis
- neisseria gonorrhoeae
- Prior art date
Links
- 208000001860 Eye Infections Diseases 0.000 title claims 5
- 208000011323 eye infectious disease Diseases 0.000 title claims 5
- 241000588652 Neisseria gonorrhoeae Species 0.000 title claims 3
- 238000011321 prophylaxis Methods 0.000 title claims 3
- 238000011282 treatment Methods 0.000 title claims 3
- 150000001875 compounds Chemical class 0.000 claims 10
- YWWVWXASSLXJHU-AATRIKPKSA-N (9E)-tetradecenoic acid Chemical compound CCCC\C=C\CCCCCCCC(O)=O YWWVWXASSLXJHU-AATRIKPKSA-N 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical compound CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 claims 4
- YWWVWXASSLXJHU-UHFFFAOYSA-N 9E-tetradecenoic acid Natural products CCCCC=CCCCCCCCC(O)=O YWWVWXASSLXJHU-UHFFFAOYSA-N 0.000 claims 2
- 239000002738 chelating agent Substances 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 2
- SECPZKHBENQXJG-FPLPWBNLSA-N palmitoleic acid Chemical compound CCCCCC\C=C/CCCCCCCC(O)=O SECPZKHBENQXJG-FPLPWBNLSA-N 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 235000021319 Palmitoleic acid Nutrition 0.000 claims 1
- SECPZKHBENQXJG-UHFFFAOYSA-N cis-palmitoleic acid Natural products CCCCCCC=CCCCCCCCC(O)=O SECPZKHBENQXJG-UHFFFAOYSA-N 0.000 claims 1
- 239000006196 drop Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- -1 fatty acid ester Chemical class 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229960002446 octanoic acid Drugs 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/06—Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (9)
1. Spoj koji je masna kiselina ili ester masne kiseline, ili farmaceutski prihvatljiva sol ili solvat istog, odabran od miristoleinske kiseline C14:1cA9, palmitoleinske kiseline C16:1cA9 i monoglicerida kaprilne kiseline C10:0 (monokaprin C10), za primjenu u okularnom liječenju ili profilaksi infekcije oka izazvane sa Neisseria gonorrhoeae kod toplokrvnih životinja.
2. Spoj za primjenu prema patentnom zahtjevu 1, pri čemu je spoj miristoleinska kiselina C14:1cA9, ili monoglicerid kaprilne kiseline C10:0 (monokaprin C10), ili solvat istog.
3. Spoj za primjenu prema patentnom zahtjevu 1, pri čemu spoj je monoglicerid kaprilne kiseline C10:0 (monokaprin C10).
4. Spoj za primjenu prema bilo kojem od prethodnih patentnih zahtjeva, pri čemu je spoj u oftalmološkoj formulaciji koja sadrži kelatni agens.
5. Spoj za primjenu prema bilo kojem od prethodnih patentnih zahtjeva, pri čemu je infekcija oka kod čovjeka.
6. Spoj za primjenu prema bilo kojem od prethodnih patentnih zahtjeva, pri čemu je infekcija oka kod novorođenčeta.
7. Oftalmološka formulacija koja sadrži spoj kako je definirano u bilo kojem od patentnih zahtjeva 1 do 3, i farmaceutski prihvatljiv nosač, za primjenu u okularnom liječenju ili profilaksi infekcije oka izazvane sa Neisseria gonorrhoeae.
8. Formulacija za primjenu prema patentnom zahtjevu 7, u obliku tekućih kapi, masti ili hidrogela za oči.
9. Formulacija za primjenu prema patentnom zahtjevu 7 ili patentnom zahtjevu 8, koja dalje sadrži kelatni agens.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1701450.7A GB2559173A (en) | 2017-01-30 | 2017-01-30 | Prophylaxis and treatment of neisseria Gonorrhoeae eye infection |
| EP18154222.6A EP3354264B1 (en) | 2017-01-30 | 2018-01-30 | Prophylaxis and treatment of neisseria gonorrhoeae eye infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20211260T1 true HRP20211260T1 (hr) | 2021-11-12 |
| HRP20211260T8 HRP20211260T8 (hr) | 2021-11-26 |
Family
ID=58462880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20211260TT HRP20211260T8 (hr) | 2017-01-30 | 2021-08-04 | Profilaksa i liječenje neisseria gonorrhoeae očne infekcije |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP3354264B1 (hr) |
| ES (1) | ES2886977T3 (hr) |
| GB (1) | GB2559173A (hr) |
| HR (1) | HRP20211260T8 (hr) |
| PL (1) | PL3354264T3 (hr) |
| SI (1) | SI3354264T1 (hr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3349589B1 (en) | 2015-09-16 | 2022-12-14 | Apeel Technology, Inc. | Method for forming a protective coating by applying fatty acid glyceride compounds to a surface |
| EP3407713A1 (en) | 2016-01-26 | 2018-12-05 | Apeel Technology, Inc. | Method for preparing and preserving sanitized products |
| MX2022010392A (es) | 2020-03-04 | 2022-09-05 | Apeel Tech Inc | Productos agricolas recubiertos y metodos correspondientes. |
| EP4237400A1 (en) | 2020-10-30 | 2023-09-06 | Apeel Technology, Inc. | Compositions and methods of preparation thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1302280C (en) * | 1986-04-21 | 1992-06-02 | Jon Joseph Kabara | Topical antimicrobial pharmaceutical compositions and methods |
| CN101938999A (zh) * | 2007-12-04 | 2011-01-05 | 韦斯特盖特生物有限公司 | 包含脂肪酸和乳蛋白的抗微生物组合物 |
-
2017
- 2017-01-30 GB GB1701450.7A patent/GB2559173A/en not_active Withdrawn
-
2018
- 2018-01-30 PL PL18154222T patent/PL3354264T3/pl unknown
- 2018-01-30 SI SI201830374T patent/SI3354264T1/sl unknown
- 2018-01-30 EP EP18154222.6A patent/EP3354264B1/en active Active
- 2018-01-30 ES ES18154222T patent/ES2886977T3/es active Active
-
2021
- 2021-08-04 HR HRP20211260TT patent/HRP20211260T8/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2886977T3 (es) | 2021-12-21 |
| EP3354264B1 (en) | 2021-06-02 |
| PL3354264T3 (pl) | 2021-11-02 |
| SI3354264T1 (sl) | 2021-11-30 |
| HRP20211260T8 (hr) | 2021-11-26 |
| GB2559173A (en) | 2018-08-01 |
| GB201701450D0 (en) | 2017-03-15 |
| EP3354264A1 (en) | 2018-08-01 |
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