HRP20211186T1 - Sredstvo za ispiranje usta na bazi klorheksidina za prevenciju zubnih mrlja - Google Patents
Sredstvo za ispiranje usta na bazi klorheksidina za prevenciju zubnih mrlja Download PDFInfo
- Publication number
- HRP20211186T1 HRP20211186T1 HRP20211186TT HRP20211186T HRP20211186T1 HR P20211186 T1 HRP20211186 T1 HR P20211186T1 HR P20211186T T HRP20211186T T HR P20211186TT HR P20211186 T HRP20211186 T HR P20211186T HR P20211186 T1 HRP20211186 T1 HR P20211186T1
- Authority
- HR
- Croatia
- Prior art keywords
- chlorhexidine
- hydroxyacetophenone
- staining
- composition according
- salt
- Prior art date
Links
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title claims 4
- 229960003260 chlorhexidine Drugs 0.000 title claims 4
- 239000002324 mouth wash Substances 0.000 title claims 2
- 229940051866 mouthwash Drugs 0.000 title claims 2
- 206010044032 Tooth discolouration Diseases 0.000 title 1
- 230000036344 tooth staining Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 7
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 4
- JECYUBVRTQDVAT-UHFFFAOYSA-N 2-acetylphenol Chemical compound CC(=O)C1=CC=CC=C1O JECYUBVRTQDVAT-UHFFFAOYSA-N 0.000 claims 2
- MLSJBGYKDYSOAE-DCWMUDTNSA-N L-Ascorbic acid-2-glucoside Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1O MLSJBGYKDYSOAE-DCWMUDTNSA-N 0.000 claims 2
- 229940067599 ascorbyl glucoside Drugs 0.000 claims 2
- LUJMEECXHPYQOF-UHFFFAOYSA-N 3'-Hydroxyacetophenone Natural products CC(=O)C1=CC=CC(O)=C1 LUJMEECXHPYQOF-UHFFFAOYSA-N 0.000 claims 1
- 208000002064 Dental Plaque Diseases 0.000 claims 1
- 208000002925 dental caries Diseases 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0063—Periodont
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (5)
1. Kompozicija koja sadrži klorheksidin ili njegovu sol, askorbil glukozid i hidroksiacetofenon, pri čemu je hidroksiacetofenon odabran među izomernim oblicima para-hidroksiacetofenona, meta-hidroksiacetofenona, orto-hidroksiacetofenona ili njihovih smjesa i navedena kompozicija je za lokalno-oralnu upotrebu.
2. Kompozicija prema patentnom zahtjevu 1, pri čemu su klorheksidin ili njegova sol od toga sadržani u količini između 0,02% i 2% (m/m), askorbil glukozid je sadržan u količini između 0,08% i 5% (m/m), i hidroksiacetofenon je sadržan u količini između 0,02% i 2% (m/m).
3. Kompozicija prema bilo kojem od patentnih zahtjeva 1 i 2, pri čemu je navedena sol klorheksidina odabrana između diglukonat, diacetat ili diklorohidrat soli.
4. Kompozicija prema bilo kojem od patentnih zahtjeva 1 do 3 za primjenu u prevenciji zubnih naslaga i karijesa.
5. Kompozicija prema bilo kojem od patentnih zahtjeva 1 do 3 u obliku sredstva za ispiranje usta, paste za zube, gela.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102017000022601A IT201700022601A1 (it) | 2017-02-28 | 2017-02-28 | Collutorio a base di clorexidina anti-imbrunimento dentale. |
| EP18712463.1A EP3589374B1 (en) | 2017-02-28 | 2018-02-27 | Chlorhexidine-based mouthwash preventing teeth-staining |
| PCT/IB2018/051233 WO2018158683A1 (en) | 2017-02-28 | 2018-02-27 | Chlorhexidine-based mouthwash preventing teeth-staining |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20211186T1 true HRP20211186T1 (hr) | 2021-10-29 |
Family
ID=59579811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20211186TT HRP20211186T1 (hr) | 2017-02-28 | 2021-07-23 | Sredstvo za ispiranje usta na bazi klorheksidina za prevenciju zubnih mrlja |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP3589374B1 (hr) |
| ES (1) | ES2884748T3 (hr) |
| HR (1) | HRP20211186T1 (hr) |
| IT (1) | IT201700022601A1 (hr) |
| PT (1) | PT3589374T (hr) |
| SI (1) | SI3589374T1 (hr) |
| WO (1) | WO2018158683A1 (hr) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20020421A1 (it) * | 2002-03-01 | 2003-09-01 | Restituita Castellaccio | Colluttorio per l'igiene orale a base di clorexidina |
| FR2972347B1 (fr) * | 2011-03-11 | 2013-04-12 | Pf Medicament | Composition de soin et/ou d'hygiene bucco-dentaire |
| PL2774481T3 (pl) * | 2013-03-08 | 2019-03-29 | Symrise Ag | Kompozycje przeciwdrobnoustrojowe |
| ES2819207T3 (es) * | 2014-04-29 | 2021-04-15 | Symrise Ag | Mezclas activas |
-
2017
- 2017-02-28 IT IT102017000022601A patent/IT201700022601A1/it unknown
-
2018
- 2018-02-27 EP EP18712463.1A patent/EP3589374B1/en active Active
- 2018-02-27 WO PCT/IB2018/051233 patent/WO2018158683A1/en unknown
- 2018-02-27 SI SI201830359T patent/SI3589374T1/sl unknown
- 2018-02-27 PT PT187124631T patent/PT3589374T/pt unknown
- 2018-02-27 ES ES18712463T patent/ES2884748T3/es active Active
-
2021
- 2021-07-23 HR HRP20211186TT patent/HRP20211186T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IT201700022601A1 (it) | 2018-08-28 |
| EP3589374A1 (en) | 2020-01-08 |
| ES2884748T3 (es) | 2021-12-13 |
| SI3589374T1 (sl) | 2021-11-30 |
| WO2018158683A1 (en) | 2018-09-07 |
| PT3589374T (pt) | 2021-08-19 |
| EP3589374B1 (en) | 2021-05-19 |
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